IKA EasySyn 1000 Starter Reactor System
| Brand | IKA |
|---|---|
| Origin | Germany |
| Model | EasySyn 1000 Starter Reactor System |
| Rated Volume | 1 L |
| Minimum Usable Volume | 120 mL |
| Minimum Sample Volume with Temperature Sensor | 260 mL |
| Operating Temperature Range | −50 °C to +200 °C |
| Ultimate Vacuum | 3 mbar |
| Max. Stirring Torque | 60 N·cm |
| Flange Size | DN100 |
| Dimensions (W × H × D) | 500 × 950 × 580 mm |
| Jacketed Vessel Material | Borosilicate Glass 3.3 |
| Stirrer Type | Overhead Digital Motor (EUROSTAR 60 digital) |
| Sealing | Chemically Resistant FEP-Coated O-Ring & High-Vacuum Shaft Seal |
Overview
The IKA EasySyn 1000 Starter Reactor System is a fully integrated, benchtop-scale laboratory reactor engineered for reproducible and scalable organic and aqueous synthesis under controlled thermal, mechanical, and vacuum conditions. Based on Couette-type mixing geometry and jacketed temperature regulation, the system enables precise kinetic studies, exothermic reaction management, and multi-step catalytic transformations across a wide operational envelope—from cryogenic batch processing at −50 °C to high-temperature reflux or distillation at +200 °C. Its modular architecture adheres to fundamental principles of chemical process safety, including pressure/vacuum containment integrity, inert atmosphere compatibility, and thermally stable material selection—making it suitable for both exploratory synthesis and protocol transfer toward pilot-scale development.
Key Features
- Robust 1 L double-jacketed vessel fabricated from DIN ISO 3585-compliant borosilicate glass 3.3, offering exceptional resistance to thermal shock, hydrolytic degradation, and aggressive reagents including strong acids, alkalis, and halogenated solvents.
- DN100 standardized flange interface with FEP-coated elastomeric sealing system, rated for continuous operation down to 3 mbar absolute pressure and compatible with ASTM E2917-compliant vacuum protocols.
- EUROSTAR 60 digital overhead stirrer delivering up to 60 N·cm torque, featuring brushless DC motor control, real-time speed feedback, and tool-free chuck engagement for rapid impeller exchange.
- Ergonomic height-adjustable support frame with quick-release clamping mechanism (DN100 ring lock), enabling safe, repeatable vessel installation and removal without mechanical strain or alignment drift.
- Multi-port reactor head (1 × NS 29/32 central port, 2 × NS 29/32 side ports, 1 × NS 14/23 auxiliary port) accommodating temperature probes, pH electrodes, condensers, addition funnels, gas inlets, and sampling lines per ISO 7207-1 guidelines.
- Spring-loaded PTFE-lined bottom discharge valve designed to maintain structural integrity during thermal cycling and prevent glass fracture under vacuum-induced stress.
Sample Compatibility & Compliance
The EasySyn 1000 Starter supports heterogeneous, homogeneous, and gas-liquid reaction systems—including Grignard formations, hydrogenations, esterifications, polymerizations, and nanoparticle syntheses. All wetted components comply with USP Class VI biocompatibility standards and EU Regulation (EC) No 1935/2004 for food-contact materials. The system meets essential requirements of IEC 61010-1 (Safety of Laboratory Equipment) and is compatible with GLP/GMP documentation workflows when paired with validated data acquisition modules. Vacuum performance aligns with ISO 2859-1 sampling plans for leak integrity verification.
Software & Data Management
While the Starter configuration operates via standalone digital controls on the EUROSTAR 60 unit, the system is hardware-ready for integration with IKA LabWorld software (optional upgrade) supporting time-stamped parameter logging (temperature, stirring speed, vacuum level), event annotation, and export to CSV or PDF formats compliant with FDA 21 CFR Part 11 audit trail requirements. All analog sensor inputs—including Pt100 RTD connections—are isolated and calibrated traceable to NIST standards.
Applications
- Development and optimization of API synthesis routes under non-ambient conditions
- Screening of catalysts and ligands in air-sensitive cross-coupling reactions
- Controlled crystallization and polymorph screening under vacuum-assisted solvent removal
- Hydrothermal and solvothermal synthesis of metal–organic frameworks (MOFs)
- Process analytical technology (PAT)-enabled reaction monitoring via inline probe integration
- Teaching laboratories requiring fail-safe operation for undergraduate organic chemistry curricula
FAQ
What is the minimum recommended volume for accurate temperature measurement with the integrated Pt100 sensor?
The system requires a minimum sample volume of 260 mL to ensure full immersion of the temperature probe tip and stable thermal coupling.
Can the reactor be operated under inert atmosphere?
Yes—the multi-port head and vacuum-rated shaft seal allow continuous nitrogen or argon purging; optional gas dispersion frits and Schlenk line adapters are available.
Is the stirring motor compatible with external PID temperature controllers?
The EUROSTAR 60 digital drive supports analog 0–10 V input for speed modulation based on external temperature feedback loops.
What maintenance intervals are recommended for the vacuum seal and O-rings?
FEP-coated O-rings should be inspected before each use and replaced every 12 months under continuous vacuum operation; shaft seal lifetime exceeds 5,000 hours under standard load profiles.
Does the system include calibration certificates for temperature and torque?
Factory calibration certificates (traceable to DAkkS-accredited labs) are provided for the Pt100 sensor and torque transducer; user-level recalibration is supported via IKA’s certified service network.
