Ismatec REGLO ICC Digital 3-Channel Peristaltic Pump
| Brand | ISMATEC |
|---|---|
| Origin | USA |
| Model | 78001-70 |
| Flow Rate Range | 0.001–35 mL/min |
| Speed Range | 1–100 rpm |
| Channels | 3 |
| Roller Count | 8 |
| Accuracy | ±1% |
| Duty Cycle | Continuous |
| Max Pressure | 1 bar (14.5 psi) |
| Input Power | 100–240 VAC, 50/60 Hz |
| Control Interface | USB + RS-232 |
| Flow Direction | Bidirectional per channel |
Overview
The Ismatec REGLO ICC Digital 3-Channel Peristaltic Pump is a precision-engineered laboratory fluid handling instrument designed for applications requiring independent, synchronized, or staggered flow control across three discrete channels. Based on the well-established peristaltic principle—where rollers compress flexible tubing to generate positive displacement—the pump delivers pulse-free, contamination-free fluid transfer without exposing internal components to the process medium. Its digital variable-speed architecture enables precise volumetric delivery from 0.001 mL/min up to 35 mL/min per channel, with speed resolution of 1 rpm and repeatability consistent with ±1% accuracy under calibrated conditions. The 8-roller head design ensures smooth flow profiles, reduced pulsation, and extended tube life compared to lower-roller configurations—critical for sensitive assays, cell culture media perfusion, and reagent dosing in analytical workflows.
Key Features
- Independent digital control of speed, direction, and start/stop for each of three channels via front-panel keypad or host computer
- Bidirectional flow capability per channel—enabling recirculation, backflushing, and reversible dosing protocols
- Integrated USB 2.0 interface for plug-and-play communication; optional RS-232 port supports legacy SCADA or LIMS integration
- Pre-calibrated channel-specific flow correction algorithms compensate for tube elasticity, wall thickness variation, and roller wear—minimizing inter-channel deviation
- Modular quick-change tubing cassette system (compatible with standard Ismatec-compatible silicone or PharMed® BPT tubing) reduces setup time and cross-contamination risk
- Robust switching power supply (100–240 VAC, 50/60 Hz) ensures stable operation across global laboratory power infrastructures
- Continuous-duty rated motor and thermally managed drive electronics support unattended 24/7 operation in incubators or enclosed automation platforms
Sample Compatibility & Compliance
The REGLO ICC accommodates standard inner diameters from 0.5 mm to 4.8 mm (e.g., Tygon® LFL, Masterflex® Norprene®, or C-Flex® tubing), supporting aqueous buffers, organic solvents, mild acids/bases, and shear-sensitive biological fluids—including whole blood, cell suspensions, and protein formulations—provided tubing material compatibility is verified. The pump complies with IEC 61010-1:2010 for electrical safety in laboratory equipment and meets EMC requirements per EN 61326-1:2013. While not intrinsically rated for hazardous locations, its non-sparking brushless DC motor and absence of seals or valves make it suitable for use in ISO Class 5–7 cleanrooms when paired with appropriate tubing and housing. For regulated environments (e.g., pharmaceutical QC labs), audit trail functionality can be implemented via external software logging of USB command sequences in alignment with FDA 21 CFR Part 11 principles.
Software & Data Management
The pump operates natively with Ismatec’s free REGLO PC Software (Windows 7–11), enabling real-time monitoring of RPM, direction status, and elapsed runtime per channel. Users may define multi-step programs—including ramped acceleration, timed intervals, and conditional triggers—and export timestamped CSV logs for traceability. Command-line control via ASCII-based RS-232 protocol allows seamless integration into Python, LabVIEW, or MATLAB-driven automation frameworks. All firmware updates are delivered via signed HEX files through the USB interface, ensuring version control and integrity verification. No proprietary drivers are required—USB CDC class compliance enables OS-native enumeration on Linux and macOS systems.
Applications
- Multi-stream reagent addition in automated titration or kinetic ELISA platforms
- Parallel perfusion of 3D tissue constructs or microfluidic organ-on-chip devices
- Gradient solvent delivery in preparative HPLC or inline dialysis systems
- Controlled feeding and harvest cycles in bioreactor auxiliary loops
- Calibration standard delivery in flow cytometry or particle counting instrumentation
- Waste aspiration and buffer exchange in automated Western blotting or nucleic acid purification workstations
FAQ
Can the pump maintain accurate flow rates with varying backpressure?
Yes—within its specified maximum pressure limit of 1 bar, flow rate stability is maintained by closed-loop speed regulation. However, significant downstream resistance (>0.5 bar) may reduce effective flow; users should select tubing with appropriate wall thickness and ID to match system impedance.
Is tubing calibration required for each channel?
While factory calibration provides baseline accuracy, optimal performance requires user-performed volumetric calibration using gravimetric or timed-collection methods for each tubing type and ID installed—particularly when operating below 1 mL/min.
Does the pump support analog input/output for external process control?
No—the REGLO ICC is digitally controlled only via USB or RS-232. Analog interfacing requires an external PLC or DAQ module configured to translate voltage signals into serial commands.
What is the expected service life of the roller mechanism?
Under continuous operation at ≤80 rpm with proper tube selection, the hardened steel roller assembly is rated for ≥20,000 hours before maintenance inspection—consistent with ISO 9001-compliant manufacturing validation data.
