Jiapeng BS-160A Automatic Fraction Collector

Overview

The Jiapeng BS-160A Automatic Fraction Collector is a precision-engineered time-triggered fractionation device designed for integration into low-to-medium pressure liquid chromatography (LC) and column chromatography systems. It operates on the principle of programmable timed eluate segmentation—capturing sequential fractions of effluent at user-defined intervals—enabling reproducible isolation of target compounds during purification processes. Engineered for reliability in preparative-scale biochemical separation labs, the BS-160A supports consistent fraction collection across extended runs (≥200 hours continuous operation), with robust power-loss resilience ensuring experimental integrity even under unexpected outages. Its architecture prioritizes operational safety, ergonomic accessibility, and compatibility with standard chromatographic workflows—including gradient elution and multi-pump configurations.

Key Features

• High-capacity 160-tube circular tray with laser-etched digital numbering—ensures unambiguous tube identification and eliminates misalignment during automated tube exchange.
• Microprocessor-controlled timing engine with adjustable resolution from 1 second to 24 hours; supports both forward and reverse countdown modes for flexible protocol sequencing.
• Six-digit ultra-bright LED display for real-time visibility of elapsed time, active tube index, and parameter status—optimized for lab environments with variable ambient lighting.
• Integrated Keebio solenoid shut-off valve with rapid response (<100 ms actuation) and chemical resistance to common organic solvents (e.g., acetonitrile, methanol, chloroform), minimizing carryover between fractions.
• Ergonomic 35° inclined control panel—designed to reduce operator fatigue during prolonged setup and monitoring sessions.
• Non-volatile memory retains all configuration parameters—including timing presets, start/end tube indices, and valve calibration offsets—for up to 10 years without battery backup or external power.
• RS-232 serial interface enables hardware-level synchronization with compatible peristaltic or piston-driven LC pumps, supporting external trigger initiation and pause/resume commands.

Sample Compatibility & Compliance

The BS-160A accommodates standard 12 × 75 mm or 13 × 100 mm test tubes (5 mL nominal volume), with optional solvent-resistant trays available for use with aggressive mobile phases. Its sealed ABS housing meets IEC 61010-1 requirements for laboratory electrical equipment safety. While not certified to ISO/IEC 17025 or FDA 21 CFR Part 11 out-of-the-box, the device supports audit-ready operation when deployed within validated chromatography systems—particularly where timestamped fraction logs, parameter traceability, and manual intervention records are maintained per GLP or internal SOPs. It is routinely employed in applications aligned with USP , EP 2.2.46, and ASTM D7091 methodologies for compound isolation and purity assessment.

Software & Data Management

The BS-160A operates as a standalone hardware controller with no embedded operating system or network stack. All configuration is performed locally via front-panel keypad input. Timestamped collection events are not logged to internal storage beyond parameter retention; however, when paired with a synchronized pump equipped with data export capability (e.g., via RS-232 or analog output), fraction metadata—including start time, duration, and tube position—can be captured externally using third-party acquisition software (e.g., LabVIEW, MATLAB, or custom Python scripts). This architecture ensures deterministic behavior and eliminates firmware-related variability—a critical consideration in regulated environments where instrument qualification must demonstrate functional consistency over time.

Applications

• Purification of natural products (e.g., alkaloids, flavonoids, terpenes) from plant extracts via silica gel or reversed-phase column chromatography.
• Isolation of recombinant proteins and monoclonal antibodies following size-exclusion or ion-exchange chromatography.
• Fractionation of synthetic reaction mixtures for intermediate characterization and byproduct removal.
• Preparative HPLC fraction collection in pharmaceutical development labs adhering to ICH Q5A–Q5E guidelines.
• Quality control sampling in biomanufacturing processes where temporal resolution of elution profiles informs lot release decisions.

FAQ

Does the BS-160A support volume-based collection?
No—the BS-160A implements time-based fractionation only. Volume-triggered collection requires integration with a flowmeter-equipped pump system and external logic control.
Can the tube tray be interchanged with other Jiapeng models?
Yes—trays for the BS-160A series are mechanically and dimensionally compatible with BSZ-160 and BS-100A units, enabling cross-model workflow standardization.
Is the RS-232 interface optically isolated?
No—standard RS-232 signaling is used; galvanic isolation must be implemented externally if required for noise-sensitive environments.
What maintenance is recommended for long-term valve performance?
Keebio valves should be flushed with deionized water after exposure to viscous or salt-containing buffers; annual inspection of O-ring integrity is advised.
Does the unit comply with CE or UL safety standards?
It conforms to GB 4793.1–2007 (Chinese national equivalent of IEC 61010-1); CE or UL certification is not held by default but may be pursued via authorized regional representatives.