KNF FP1.25 Low-Pulsation Diaphragm Liquid Pump
| Brand | KNF |
|---|---|
| Origin | Switzerland |
| Pump Type | Diaphragm Pump |
| Product Category | Oil-Free Liquid Transfer Pump |
| Maximum Flow Rate | 0.25 L/min |
| Maximum Operating Pressure | 6 bar (rel.) |
| Maximum Suction Lift | 3 mWg |
| Motor Power | 3.6 W |
| Weight | 240 g |
| Diaphragm Materials | EPDM, PTFE |
| Valve Materials | EPDM, FFKM |
| Pump Head Material | PPS |
| Motor Options | DC, Brushless DC |
| Certifications | NSF, FDA |
| Control Options | Digitally Adjustable Speed, Programmable Performance |
Overview
The KNF FP1.25 is a compact, high-integrity diaphragm liquid pump engineered for precise, contamination-free transfer of neutral and aggressive liquids in demanding laboratory and analytical applications. Based on KNF’s proven electromechanical diaphragm displacement principle, the FP1.25 operates without lubricants or internal seals—eliminating risk of media contamination and enabling true dry-run capability. Its low-pulsation fluid delivery (typically < ±2% peak-to-peak flow variation under steady-state conditions) ensures stable pressure profiles critical for microfluidic dosing, reagent delivery in HPLC autosamplers, and continuous-flow analytical systems. Designed and manufactured in Switzerland, the FP1.25 complies with stringent European CE directives and integrates seamlessly into ISO 17025-accredited laboratories where traceability, repeatability, and material compatibility are non-negotiable.
Key Features
- Low-pulsation operation optimized for sensitive fluid handling—ideal for analytical instrumentation requiring stable flow profiles
- Fully oil-free, maintenance-free architecture with no sliding parts or lubricants; eliminates cross-contamination risk
- Self-priming capability up to 3 mWg suction lift—enables reliable start-up from dry or flooded conditions
- Chemically resistant wetted materials: PPS pump head, EPDM or PTFE diaphragms, and EPDM/FFKM valve assemblies compatible with acids, bases, solvents, and halogenated media
- Digitally adjustable brushless DC motor with linear speed control (0–100% range), supporting analog 0–10 V or PWM input for integration into automated platforms
- Compact footprint (98 × 54 × 42 mm) and ultra-light mass (240 g) facilitate OEM integration into space-constrained instruments
- NSF/ANSI 51 and FDA 21 CFR Part 177-compliant materials—validated for food contact and pharmaceutical-grade fluid paths
- EMC-compliant design meeting EN 61326-1 for use in regulated laboratory environments
Sample Compatibility & Compliance
The FP1.25 is validated for continuous-duty transfer of aqueous solutions, organic solvents (e.g., methanol, isopropanol), dilute mineral acids (up to 10% HCl, HNO₃), caustic solutions (up to 5% NaOH), and peroxide-based disinfectants. Its wetted path conforms to USP Class VI biocompatibility testing and meets ISO 10993-5 cytotoxicity requirements. For regulated environments, the pump supports GLP/GMP workflows through optional firmware logging of runtime hours, motor temperature, and cumulative stroke count—traceable via RS-485 Modbus RTU interface. All material declarations (EPDM, PTFE, PPS) are supplied with full RoHS and REACH documentation upon request.
Software & Data Management
While the FP1.25 operates as a standalone analog-controlled pump, its brushless DC motor enables full digital integration via standard industrial protocols. When paired with KNF’s optional KF-Link controller or third-party PLCs, users can configure ramp-up/down profiles, set flow thresholds with alarm outputs, and log operational parameters—including real-time current draw (proxy for load condition) and thermal derating status. Firmware updates are performed via UART, and configuration persistence survives power cycles. Audit trails comply with FDA 21 CFR Part 11 when deployed with validated SCADA systems that enforce electronic signatures and change control.
Applications
- Reagent metering in clinical analyzers and IVD platforms
- Sample aspiration and waste evacuation in portable gas chromatography and emission monitoring systems
- Precision dosing in semiconductor wet benches and photoresist dispensing units
- Cleaning-fluid circulation in CIP/SIP modules for bioreactor support systems
- Fuel and humidification fluid delivery in PEM fuel cell test stations
- Controlled ink transport in industrial inkjet printheads requiring pulse-free supply
- Media perfusion in organ-on-chip and microphysiological systems
FAQ
Is the FP1.25 suitable for sterile or aseptic applications?
Yes—when equipped with PTFE diaphragms and EPDM valves, and operated within validated cleaning protocols (e.g., SIP at 121°C for 15 min), the FP1.25 maintains integrity in Class A/B cleanroom environments.
Can it handle viscous fluids above 100 cP?
It is rated for viscosities up to 200 cP at 20°C; performance degrades above this threshold due to reduced volumetric efficiency—consult KNF’s application engineering team for viscosity-specific derating curves.
Does the pump require periodic calibration?
No—flow accuracy is inherent to the fixed-displacement diaphragm geometry and motor step resolution; however, system-level flow verification using gravimetric or transit-time ultrasonic methods is recommended per ISO 8599 for critical dosing applications.
What is the expected service life under continuous operation?
Rated for ≥20,000 hours MTBF at 50% duty cycle and ambient temperatures ≤40°C—validated per IEC 60068-2 environmental stress screening.

