LabTech PrepElite-GVS Automated Multi-Module Sample Preparation Platform
| Brand | LabTech |
|---|---|
| Origin | USA |
| Manufacturer | LabTech |
| Product Category | Imported |
| Model | GVS |
| Pricing | Upon Request |
| Flow Rate | Not Applicable |
| Maximum Pressure | Not Applicable |
| Flow Stability | Not Applicable |
| Auto-sampling Volume | Not Applicable |
| Auto-sampling Capacity | Not Applicable |
Overview
The LabTech PrepElite-GVS Automated Multi-Module Sample Preparation Platform is an integrated, modular gel permeation chromatography (GPC)-based sample cleanup system engineered for high-throughput, reproducible purification of complex biological and environmental matrices. It operates on the principle of size-exclusion chromatography, where macromolecular interferences—such as lipids, triglycerides, pigments, and polymeric residues—are separated from target analytes (e.g., pesticides, PCBs, PAHs, mycotoxins) based on hydrodynamic volume in a cross-linked polystyrene-divinylbenzene gel column. Unlike conventional offline GPC systems, the PrepElite-GVS enables seamless online coupling between GPC purification, dual-stage vacuum concentration, and optional solid-phase extraction (SPE), eliminating manual transfer, minimizing analyte loss, and reducing solvent exposure. Designed for laboratories requiring regulatory-compliant workflows, the platform supports unattended 24/7 operation under controlled inert atmosphere, with full system sealing to prevent solvent evaporation, oxidation, or contamination.
Key Features
- Modular architecture supporting independent or fully integrated operation of GPC, dual-vacuum concentration, and SPE modules
- GPC module equipped with dual-piston precision solvent delivery pump and variable-wavelength UV detector (190–600 nm) for real-time fraction monitoring
- Dual-concentrator design: two thermally isolated concentration cups operate alternately or in parallel, enabling continuous processing without downtime
- Full-sample injection capability—no pre-dilution or volume restriction—ensuring quantitative recovery of trace analytes
- Sealed, inert-gas purged fluidic path throughout all modules to preserve labile compounds and meet GLP/GMP handling requirements
- Customizable sample rack configuration: accepts standard 10–30 mL vials, 96-well plates, and custom-format trays; position mapping programmable per method
- Bilingual (English/Chinese) touchscreen HMI with role-based user access control and audit-trail-enabled method storage
Sample Compatibility & Compliance
The PrepElite-GVS accommodates diverse sample types including crude lipid extracts from edible oils, animal tissues, dairy products, soil/sediment extracts, wastewater concentrates, and plant homogenates. Its robust GPC column (stainless-steel housing, 10–50 µm bead diameter, 100–1000 Å pore range) tolerates particulate-laden injections when paired with inline filtration. The system complies with key analytical standards including EPA Method 3640A (GPC cleanup), ASTM D7066 (lipid removal in biodiesel), and ISO 17025–accredited laboratory operational requirements. All hardware and software components support 21 CFR Part 11–compliant electronic records through timestamped, operator-locked method logs, change history tracking, and encrypted data export.
Software & Data Management
Controlled via LabTech’s PrepElite Control Suite v4.x, the platform provides method-driven automation with drag-and-drop sequence builder, real-time chromatogram overlay, and adaptive fraction triggering based on UV absorbance thresholds. Raw data—including pump pressure traces, UV chromatograms, concentrator temperature profiles, and valve actuation logs—are stored in vendor-neutral .csv and .mzML-compatible formats. Integrated report generation supports customizable templates aligned with ISO/IEC 17025 reporting clauses. Data integrity safeguards include automatic backup to network drives, SHA-256 hash verification of archived methods, and optional integration with LIMS via RESTful API.
Applications
- Routine pesticide residue analysis in fruits, vegetables, and cereals per EU SANTE/11312/2021 guidelines
- Lipid removal prior to GC-MS/MS analysis of dioxins and furans in fish tissue (EPA 1613B)
- Cleanup of fatty food extracts prior to LC-MS/MS quantification of veterinary drug residues (EU 2021/808)
- Preparative-scale isolation of natural product fractions from algal or fungal extracts
- Environmental monitoring of PAHs and alkylated benzenes in sediment porewater (ISO 18238)
- Supporting method validation studies requiring documented recovery, repeatability, and matrix effect assessment
FAQ
Does the PrepElite-GVS require external gas supply for inert atmosphere maintenance?
Yes—compressed nitrogen or argon (≥99.998% purity, 4–6 bar regulated) is required for column conditioning, fraction transfer, and concentrator headspace blanketing.
Can the GPC module be operated independently without the concentrator or SPE modules?
Yes—each module functions as a standalone instrument with dedicated control firmware and method library.
What column dimensions and packing materials are supported?
Standard configurations include 10 × 250 mm and 25 × 300 mm stainless-steel columns packed with Bio-Beads SX-3 or equivalent styrene-divinylbenzene copolymer (30–50 µm); custom columns may be validated per user request.
Is remote monitoring or troubleshooting supported?
Remote desktop access is available via secure TLS-encrypted VNC connection with prior authorization; diagnostic logs and pump calibration reports can be exported for technical review.
How is solvent consumption minimized during GPC runs?
Through programmable gradient elution, flow-rate optimization algorithms, and column re-equilibration protocols—typical solvent reduction exceeds 35% versus fixed-flow legacy systems.
