LUXIANGYI DL-6M Low-Speed High-Capacity Refrigerated Centrifuge

Overview

The LUXIANGYI DL-6M Low-Speed High-Capacity Refrigerated Centrifuge is an engineered solution for large-volume, temperature-sensitive separation tasks in clinical, biopharmaceutical, and blood banking laboratories. Designed around the principles of sedimentation centrifugation under controlled thermal conditions, the DL-6M operates at speeds up to 6,000 rpm and delivers a maximum relative centrifugal force (RCF) of 6,680 × g—optimized for pelleting large cellular components, platelets, erythrocytes, and viral particles without compromising structural integrity. Its horizontal rotor architecture supports six 1200 mL bottles or equivalent multi-bottle configurations, enabling batch processing of whole blood, plasma derivatives, cell culture harvests, and fermentation broths. The integrated dual-path refrigeration system—featuring an imported high-efficiency compressor and environmentally compliant R404a refrigerant—maintains precise temperature stability across the full operating range (−20 °C to +40 °C), critical for preserving labile biological fractions during prolonged runs.

Key Features

• High-capacity horizontal rotor accommodating up to 6 × 1200 mL containers—ideal for centralized blood banks and GMP-compliant bulk bioprocessing.
• AC frequency-controlled motor with high torque output ensures smooth acceleration/deceleration, low mechanical vibration, and acoustic performance below 65 dB(A) at rated speed.
• Microprocessor-based control system with real-time rpm/RCF interconversion, digital display (DL-6M) or optional large LCD interface (DL-6MS), and non-volatile memory for storing up to 10 user-defined protocols.
• Comprehensive safety architecture including electronic lid interlock, real-time imbalance detection, overtemperature cutoff, overspeed protection, and automatic fault logging with audible/visual alerts.
• Programmable acceleration and deceleration profiles (10 independent ramp curves) allow optimization of shear-sensitive separations—e.g., minimizing platelet activation during PRP preparation or avoiding lysosomal rupture in organelle isolation.
• Robust stainless-steel chamber construction and corrosion-resistant rotor housing meet long-term operational demands in high-throughput clinical environments.

Sample Compatibility & Compliance

The DL-6M supports standard ISO-certified centrifuge bottles (e.g., 500–1200 mL polypropylene or polycarbonate), as well as custom-configured carriers for blood bag processing. Its validated temperature control (±1 °C accuracy) aligns with requirements for component separation per AABB Technical Manual and CLSI GP44-A4 guidelines. While not pre-certified to FDA 21 CFR Part 11, the system’s parameter logging, password-protected settings, and audit-ready operational records support GLP/GMP documentation workflows. All electrical design complies with IEC 61010-1:2010 for laboratory equipment safety; refrigerant use conforms to EU F-Gas Regulation (No. 517/2014) and Montreal Protocol standards.

Software & Data Management

The DL-6M operates via embedded firmware with no external PC dependency. All run parameters—including speed, time, temperature, acceleration rate, and RCF—are stored in internal memory with timestamped execution logs. Settings persist after power cycles, eliminating reconfiguration overhead between shifts. Optional RS-232 or USB interfaces (available upon request) enable integration with LIMS platforms for automated data export. Though lacking native cloud connectivity, the unit supports CSV-formatted log extraction for traceability in quality assurance audits.

Applications

• Blood banking: Separation of packed red cells, leukocyte-reduced platelets, fresh frozen plasma, and cryoprecipitate from whole blood units.
• Biopharmaceutical manufacturing: Clarification of mammalian cell culture harvests prior to downstream chromatography.
• Virology labs: Low-speed pelleting of enveloped viruses (e.g., influenza, SARS-CoV-2) for antigen preparation or inactivation studies.
• Cell biology: Isolation of nuclei, mitochondria, and lysosomes using differential centrifugation protocols.
• Environmental microbiology: Concentration of waterborne pathogens from large-volume filtration eluates (e.g., EPA Method 1623).
• Vaccine development: Harvesting whole-cell bacterial vaccines (e.g., Mycobacterium bovis BCG) under temperature-controlled conditions.

FAQ

What is the minimum sample volume the DL-6M can process effectively with a 1200 mL bottle?
For optimal rotor balance and sedimentation efficiency, we recommend loading ≥30% of nominal bottle capacity—i.e., ≥360 mL per 1200 mL container—when operating at full speed.
Does the DL-6M support rotor validation per ISO 21501-3 or similar standards?
Rotor geometry and material certification documents are provided upon request; users must perform site-specific calibration using NIST-traceable tachometers and thermistors per ISO/IEC 17025 requirements.
Can the unit maintain −20 °C during continuous 24-hour operation?
Yes—the compressor and heat exchange system are rated for sustained operation at minimum setpoint under ambient conditions ≤25 °C and ≤60% RH.
Is rotor autoclaving supported?
No. Horizontal rotors are not designed for steam sterilization; cleaning must follow manufacturer-recommended procedures using ethanol or neutral pH disinfectants.
What voltage tolerance does the power supply accommodate?
The unit operates within ±10% of nominal 220 V AC; installation requires dedicated 30 A circuit with proper grounding per IEC 60364-5-53.