LuXiangYi TDL-5M Benchtop Low-Speed Refrigerated Centrifuge
| Brand | LuXiangYi / BIORIDGE |
|---|---|
| Origin | Shanghai, China |
| Model | TDL-5M |
| Instrument Type | Benchtop Centrifuge |
| Function | Refrigerated Centrifuge |
| Rotor Configuration | Horizontal (Swinging-Bucket) Rotor |
| Maximum Capacity | 32 × 15 mL |
| Maximum Speed | 5000 rpm |
| Maximum RCF | 4390 × g |
| Temperature Range | –5 °C to +35 °C |
| Temperature Accuracy | ±1 °C |
| Dimensions (L×W×H) | 460 mm × 710 mm × 420 mm |
| Noise Level | <65 dB(A) |
| Power Supply | AC 220 V, 50 Hz, 15 A |
| Net Weight | 80 kg |
Overview
The LuXiangYi TDL-5M Benchtop Low-Speed Refrigerated Centrifuge is a precision-engineered separation instrument designed for routine and high-throughput sedimentation of biological suspensions under controlled thermal conditions. Operating on the principle of centrifugal force-induced density-based phase separation, the TDL-5M delivers stable, reproducible performance in low-speed regimes—optimized for pelleting large cellular components including nuclei, mitochondria, lysosomes, and viral particles without inducing shear-induced structural damage. Its refrigerated architecture maintains sample integrity during extended runs, making it suitable for temperature-sensitive applications in clinical diagnostics, molecular biology, and biopharmaceutical quality control laboratories. The system integrates a high-efficiency imported compressor using environmentally compliant R22a refrigerant, enabling precise thermal regulation across its full operational range (–5 °C to +35 °C), critical for preserving enzyme activity, antigen conformation, and nucleic acid stability.
Key Features
- Microprocessor-controlled operation with AC brushless frequency-conversion motor drive—ensuring exceptional rotational stability, low mechanical noise (<65 dB[A]), and high-speed accuracy (±30 rpm).
- Intuitive capacitive touch panel interface with digital LCD display; supports real-time switching between rpm and RCF values, simplifying protocol translation across laboratory workflows.
- Programmable memory for up to 9 user-defined acceleration/deceleration profiles, allowing fine-tuned control over spin ramping to minimize sample resuspension or pellet disruption.
- Comprehensive safety architecture: electronic door interlock, automatic lid locking mechanism, overspeed protection, overtemperature cutoff, and self-diagnostic fault alerting with audible/visual indicators.
- Robust horizontal rotor design accommodating multiple interchangeable configurations—including 4 × 100 mL, 72 × 7 mL, 48 × 7 mL, and 8 × 96-well microplate carriers—enabling flexible throughput scaling without hardware reconfiguration.
Sample Compatibility & Compliance
The TDL-5M is validated for processing a broad spectrum of biospecimens, including whole blood, serum, plasma, cell culture supernatants, tissue homogenates, and clarified lysates. Its maximum relative centrifugal force of 4390 × g meets standard requirements for subcellular fractionation protocols outlined in ISO 15189, CLSI EP05-A3, and USP . Temperature control compliance (±1 °C) aligns with GLP/GMP cold-chain documentation standards for diagnostic sample preparation. While not certified for IVD use under IVDR or FDA 510(k), the device conforms to IEC 61010-1:2010 for electrical safety and EN 61326-1:2013 for electromagnetic compatibility—essential for integration into regulated laboratory environments.
Software & Data Management
The TDL-5M operates as a standalone instrument with embedded firmware supporting non-volatile parameter storage (up to 9 programs). All run logs—including start time, set speed, actual RCF, duration, final temperature, and error codes—are retained in internal memory and viewable via the front-panel interface. For traceability in auditable workflows, optional RS-232 or USB data export enables manual transfer of session records into LIMS or ELN systems. Though lacking native 21 CFR Part 11-compliant electronic signatures, the unit supports audit-ready operation when paired with external timestamped logging tools meeting ALCOA+ principles.
Applications
- Clinical laboratories: Routine serum/plasma separation prior to immunoassay, electrophoresis, or mass spectrometry analysis.
- Academic research: Isolation of intact organelles from mammalian or plant tissues using differential centrifugation gradients.
- Virology units: Concentration and purification of enveloped and non-enveloped viruses from cell culture harvests.
- Biochemistry labs: Clarification of crude enzyme extracts and precipitation of macromolecular complexes prior to chromatography.
- Quality assurance departments: Batch consistency testing of biologics, vaccines, and monoclonal antibody formulations.
FAQ
What is the maximum permissible ambient temperature for continuous operation?
The unit is rated for ambient temperatures between 10 °C and 30 °C. Operation above 30 °C may impair compressor efficiency and compromise temperature stability.
Can the TDL-5M accommodate fixed-angle rotors?
No—the TDL-5M is configured exclusively for horizontal (swinging-bucket) rotors. Fixed-angle rotor compatibility is not supported by mechanical or firmware design.
Is rotor imbalance detection integrated into the control system?
Yes. The microprocessor continuously monitors vibration signatures during acceleration and deceleration, automatically halting operation if imbalance exceeds ISO 21501-4 thresholds.
Does the device support remote monitoring or network connectivity?
No native Ethernet or Wi-Fi capability is provided. Remote status interrogation requires external serial-to-USB adapters and custom scripting.
What maintenance intervals are recommended for the refrigeration system?
Compressor oil and refrigerant levels require verification every 24 months by authorized service personnel; condenser coil cleaning is advised quarterly in high-dust environments.
