Masterflex® ISMATEC® Reglo Digital Miniflex 2-Channel 12-Roller Peristaltic Pump

Overview

The Masterflex® ISMATEC® Reglo Digital Miniflex is a high-precision, dual-channel peristaltic pump engineered for reproducible low-flow fluid handling in analytical laboratories, bioprocessing workflows, and quality control environments. Based on the positive-displacement peristaltic principle—where rollers compress flexible tubing to generate controlled, pulse-free flow—the Reglo Digital Miniflex eliminates fluid contact with internal pump components, ensuring contamination-free transfer of sensitive reagents, cell cultures, buffers, and sterile media. Its compact benchtop footprint integrates seamlessly into automated liquid handling systems or standalone applications requiring trace-level accuracy and long-term operational stability. The pump is calibrated for volumetric delivery across a wide range of tubing materials (e.g., PharMed® BPT, Tygon®, and silicone), supporting flow rates from <0.001 mL/min up to 38 mL/min per channel (dependent on tubing ID and speed setting), with inherent linearity and minimal pulsation (<2% peak-to-peak variation under standard conditions).

Key Features

• 5-inch capacitive TFT/RGB touchscreen interface with 800 × 480 resolution and 178° viewing angle—enabling intuitive navigation, real-time parameter monitoring, and graphical feedback during dispensing cycles.
• Dual independent channels with synchronized or asynchronous operation, each driven by a dedicated 12-roller pump head optimized for extended tubing life and reduced backflow.
• Three operational modes: Continuous (constant RPM), Volume (target volume with automatic stop), and Timed Dispensing (programmable ON/OFF intervals and pause durations between dispenses).
• Drip prevention algorithm actively decelerates motor rotation at endpoint to minimize residual droplet formation—critical for assay consistency and sample conservation in microvolume applications.
• Speed regulation in Volume Mode allows fine-tuning of delivery kinetics to accommodate viscosity variations without recalibrating tubing constants.
• Up to 20 user-defined protocols stored internally—including flow rate, target volume, timing parameters, and pause configurations—for rapid recall and repeatable execution.
• Three-tier access control (Operator, Supervisor, Administrator) supports role-based security, aligning with FDA 21 CFR Part 11 requirements for electronic records and signatures when integrated with compliant data management software.

Sample Compatibility & Compliance

The Reglo Digital Miniflex accommodates standard peristaltic tubing sizes ranging from 0.5 mm to 4.8 mm inner diameter, compatible with chemically resistant, USP Class VI-certified elastomers including C-Flex®, PharMed® BPT, and Norprene®. Its design conforms to IEC 61000-6-3 (EMC emissions) and IEC 61000-6-2 (immunity), and meets CE marking requirements for laboratory equipment. While not intrinsically rated for hazardous locations, it operates safely in ISO Class 5–8 cleanrooms when paired with appropriate tubing and housing enclosures. Documentation packages include Factory Acceptance Test (FAT) reports and calibration certificates traceable to NIST standards upon request.

Software & Data Management

The pump operates autonomously via its embedded firmware but supports RS-232 and USB-B connectivity for external control via LabVIEW™, Python (PySerial), or custom SCADA interfaces. Optional Masterflex PumpControl™ software enables remote configuration, real-time telemetry logging (flow rate, elapsed time, motor current), and export of CSV-formatted run logs with timestamps. Audit trail functionality records all parameter changes, user logins, and protocol executions—supporting GLP and GMP compliance in regulated pharmaceutical and clinical diagnostics settings.

Applications

• Automated reagent addition in ELISA, PCR setup, and immunoassay workstations
• Continuous perfusion in bioreactors and organ-on-chip systems
• Calibration standard delivery in HPLC and IC autosamplers
• Media exchange in stem cell culture platforms
• Low-shear transfer of shear-sensitive proteins and liposomes
• Environmental water sampling with integrated filtration manifolds

FAQ

What tubing sizes are supported by the Miniflex 12-roller pump head?
Standard configurations support inner diameters from 0.5 mm to 4.8 mm; recommended tubing wall thicknesses range from 0.8 mm to 1.6 mm for optimal occlusion and roller engagement.
Can the pump be validated for use in GMP manufacturing environments?
Yes—when deployed with documented IQ/OQ protocols, calibrated tubing sets, and configured with audit-trail-enabled software, the Reglo Digital Miniflex satisfies key elements of Annex 11 and ASTM E2500-13 for computerized system validation.
Is analog input/output available for integration with PLC-based control systems?
The pump includes 0–10 V analog input for speed control and 0–10 V analog output for real-time RPM feedback; optional digital I/O modules provide discrete start/stop and fault signaling.
How often does the tubing require replacement under continuous operation?
Lifespan varies with speed, pressure, and tubing material—typically 100–500 hours for silicone at 60 rpm; PharMed® BPT extends service life up to 1,200 hours under equivalent conditions.
Does the pump support bidirectional flow?
No—the Reglo Digital Miniflex is unidirectional by mechanical design; reversal requires manual tubing reconfiguration or use of a separate dual-directional pump model.