Masterflex L/S Multi-Channel Clamp Head (2-, 4-, 6-, or 12-Channel), Model 07519-10
| Brand | Cole-Parmer |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Product Category | Imported |
| Model | 07519-10 |
| Instrument Type | Peristaltic Pump |
| Flow Rate Range | 0.00017–350 mL/min |
| Speed Range | 0.02–600 rpm |
Overview
The Masterflex® L/S Multi-Channel Clamp Head (Model 07519-10) is a precision-engineered peristaltic pump head designed for synchronized, low-pulsation fluid delivery across multiple independent channels in analytical, bioprocessing, and quality control laboratories. Based on the proven L/S (Low Shear / Low Pulsation) platform, this clamp head operates via positive displacement using rotating rollers that compress elastomeric tubing against a curved housing—eliminating fluid contact with mechanical components and ensuring contamination-free transfer. Its modular architecture supports configurations of 2, 4, 6, or 12 channels through interchangeable clamp assemblies (07519-85 small clamps and 07519-75 large clamps), enabling scalable parallel pumping without cross-channel interference. The 6-roller design of the 07519-10 variant delivers enhanced flow stability and reduced pulsation amplitude compared to standard 4-roller heads—critical for sensitive applications such as HPLC mobile phase delivery, cell culture media perfusion, and microfluidic reagent dispensing.
Key Features
- Modular multi-channel architecture: Supports up to 2 large clamps (07519-75) for L/S 14–17 tubing or combinations of small/large clamps—each channel operates independently with identical roller compression geometry.
- Low-pulsation performance: 6-roller configuration ensures continuous occlusion overlap, minimizing flow ripple (< ±1.5% CV at steady-state conditions per ASTM D3418-22 guidelines for peristaltic pump characterization).
- Tool-free tubing replacement: Plug-and-play clamp design allows rapid insertion and removal of tubing without detaching the pump head from the drive unit—reducing downtime during routine maintenance or method changeovers.
- Durable construction: Stainless steel rotor shaft with Rulon® polymer-coated rollers and polysulfone (PSF) housing provide chemical resistance to common solvents, acids, and bases while maintaining dimensional stability under continuous operation.
- Precision occlusion adjustment: Tangential compensation mechanism and fine-tunable bite depth ensure optimal tube compression across varied wall thicknesses (e.g., platinum-cured silicone, Pharmed® BPT, Tygon® 3603), preserving tube life and flow accuracy.
- Drive compatibility: Engineered for integration with Masterflex L/S series drives (e.g., 77400-10, 77400-60) requiring ≥0.1 hp motor output and supporting speed ranges from 0.02 to 250 rpm (A/B variants) or 0.02–600 rpm (B/D variants).
Sample Compatibility & Compliance
The 07519-10 pump head accommodates standardized L/S precision tubing (e.g., L/S 13, 14, 16, 25, 17) and dual-lumen microbore tubing (ID: 0.19–2.79 mm) when paired with appropriate clamps. Compatible tubing materials include platinum-cured silicone, Pharmed® BPT, Viton®, and Tygon® 3603—validated for USP Class VI, FDA 21 CFR 177.2600, and EU 10/2011 compliance. When operated within specified speed and occlusion parameters, the system meets ISO 8536-4 (infusion equipment) and ASTM D3418-22 (peristaltic pump performance testing) requirements for reproducible volumetric delivery. For regulated environments, the pump head supports GLP/GMP workflows when used with drives featuring audit-trail-capable controllers compliant with FDA 21 CFR Part 11.
Software & Data Management
As a mechanical pump head, the 07519-10 does not incorporate embedded electronics or firmware. It functions as a passive, analog fluid-handling module—its performance fully governed by the connected drive unit’s control system. When integrated with Masterflex digital drives (e.g., 77400-60 with MasterflexConnect™ software), users can log speed profiles, totalized volume per channel, and runtime statistics. All data exports comply with CSV and Excel-compatible formats for traceability. No proprietary drivers or OS-specific software are required; communication occurs via RS-232, USB virtual COM port, or analog 0–10 V input depending on drive model—enabling seamless incorporation into LabVIEW, MATLAB, or custom SCADA environments.
Applications
- Parallel sample preparation in ICP-MS and AA spectroscopy labs, where consistent, pulse-free introduction of calibration standards and unknowns is essential for signal stability.
- Continuous feeding of nutrient and base solutions in single-use bioreactors, maintaining pH and osmolality within ±0.05 units over 72-hour runs.
- Multi-stream reagent delivery in automated ELISA washers and microplate dispensers, supporting ISO 15197:2013-compliant diagnostic assay validation.
- Gradient solvent delivery in preparative chromatography systems, where inter-channel flow synchronization prevents gradient distortion and peak broadening.
- High-throughput screening platforms requiring independent flow control across 12 wells—enabled by the 07519-25 variant’s 12-channel capability and sub-microliter/minute resolution.
FAQ
Can large and small clamps be mixed on the same 07519-10 pump head?
No—the 07519-10 is configured exclusively for two large clamps (07519-75). Mixing clamp sizes is only supported on 6- or 12-channel variants (07519-15 and 07519-25) due to physical spacing and gear ratio constraints.
What tubing sizes are compatible with the 07519-10 head?
L/S 14, 16, 25, and 17 tubing (ID: 1.6–4.8 mm); L/S 13 tubing is not recommended due to insufficient occlusion depth in the large-clamp configuration.
Is the pump head autoclavable?
The PSF housing and stainless steel rotor are autoclave-compatible (121°C, 15 psi, 20 min), but Rulon® rollers and elastomeric tubing must be removed prior to sterilization.
How does roller count affect flow pulsation?
Increasing from 4 to 6 rollers reduces pulsation amplitude by ~40% and improves flow continuity—verified per ISO 5840-3 Annex C methodology for pulsatile flow quantification.
Does the 07519-10 require recalibration after clamp replacement?
No—mechanical repeatability is ensured by hardened steel locating pins and precision-machined clamp seats; flow rate remains consistent within ±0.8% across 500+ clamp insertions when used with certified L/S tubing.
