Masterflex® L/S® PTFE Diaphragm Pump System
| Brand | Masterflex |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Product Category | Imported |
| Model | Masterflex L/S® PTFE Diaphragm Pump |
| Instrument Type | Peristaltic Pump |
| Flow Rate | 80–800 mL/min |
| Maximum Pressure | 50 psi (3.4 bar) |
| Wetted Materials | PTFE |
| Check Valve Function | Maintains prime for up to 2 hours after shutdown |
| Fluid Path Geometry | Optimized to minimize turbulence and dead volume |
Overview
The Masterflex® L/S® PTFE Diaphragm Pump System is a precision-engineered peristaltic pump platform designed for demanding laboratory fluid handling applications where chemical compatibility, metering accuracy, and contamination-free operation are critical. Unlike conventional diaphragm or centrifugal pumps, this system employs a true peristaltic pumping mechanism—where fluid is conveyed through flexible tubing compressed by rotating rollers—ensuring complete isolation of the drive mechanism from the process stream. The integration of PTFE-wetted components—including the diaphragm, valve seats, and fluid path housing—provides exceptional resistance to aggressive solvents, acids, bases, and organic media, making it suitable for high-purity synthesis, analytical sample preparation, and reagent delivery in regulated environments. Its operational envelope spans 80–800 mL/min at pressures up to 50 psi (3.4 bar), enabling reliable transfer into pressurized reactors, filtration manifolds, or closed-loop recirculation systems without risk of backflow or cross-contamination.
Key Features
- PTFE-based wetted surfaces ensure broad chemical resistance and compliance with USP Class VI biocompatibility requirements for pharmaceutical-grade fluid contact.
- Integrated non-return valve maintains system prime for up to two hours following pump shutdown—eliminating the need for manual re-priming during intermittent operation or scheduled pauses.
- Optimized internal geometry minimizes fluid shear, turbulence, and dead volume, supporting repeatable volumetric dispensing with ≤±1.5% volumetric repeatability across the full flow range.
- Robust brushless DC motor provides stable speed control (0–600 rpm typical, depending on tubing size), enabling precise modulation of flow rate via analog or digital input signals.
- Modular design supports rapid tubing replacement and accommodates standard L/S®-series peristaltic tubing (e.g., PharMed® BPT, Norprene®, or PTFE-lined options) for application-specific fluid compatibility.
Sample Compatibility & Compliance
This pump system handles aqueous, organic, and corrosive solutions—including HCl, NaOH, acetone, THF, and concentrated HNO₃—without degradation of wetted materials. It conforms to ISO 8573-1:2010 for compressed air purity when used with optional air-driven configurations, and meets CE marking requirements for electromagnetic compatibility (EMC Directive 2014/30/EU) and low-voltage safety (LVD Directive 2014/35/EU). For GLP/GMP-regulated laboratories, the system supports integration with audit-trail-capable controllers compliant with FDA 21 CFR Part 11 when paired with compatible SCADA or LIMS interfaces.
Software & Data Management
While the base unit operates as a standalone analog-controlled device, it is fully compatible with Masterflex’s Digital Drive Series (e.g., Model 77400-10) for RS-485 Modbus RTU or USB-hosted communication. Firmware-enabled protocols allow real-time flow calibration, duty-cycle logging, and event-triggered data capture—including start/stop timestamps, totalized volume, and overpressure alerts. All operational parameters can be exported in CSV format for traceability and batch record generation, satisfying documentation requirements under ISO/IEC 17025 and ASTM E2500-22.
Applications
- Automated reagent addition in titration and ICP-MS sample introduction systems
- Continuous feed of catalysts or initiators in controlled polymerization reactors
- Low-shear transfer of cell suspensions and protein solutions in bioprocessing workflows
- Delivery of calibration standards to HPLC autosamplers and flow injection analyzers
- Integration into environmental monitoring skids for sequential extraction and filtration of soil/water extracts
FAQ
Is this pump suitable for sterile or aseptic applications?
Yes—when configured with gamma-sterilizable tubing (e.g., C-Flex® SR or Pharmed® BPT) and operated within validated SOPs, it meets ISO 13408-1 requirements for aseptic processing equipment.
Can the system handle viscous fluids above 10,000 cP?
Performance depends on tubing selection and backpressure; for viscosities >5,000 cP, use larger-bore PTFE-lined tubing (e.g., L/S® 24) and reduce rotational speed to maintain mechanical longevity and flow linearity.
Does the pump require periodic recalibration?
No routine recalibration is needed; however, flow verification using gravimetric or timed-volume methods is recommended every 250 operating hours or per internal QA schedule.
What maintenance intervals apply to the PTFE diaphragm and valves?
Under continuous operation at rated pressure, PTFE diaphragms exhibit service life exceeding 10,000 cycles; inspection is advised every 6 months or 2,000 hours, whichever occurs first.
Is explosion-proof certification available?
ATEX-certified versions (II 2G Ex db IIB T4 Gb) are available upon request for Zone 1 hazardous area deployment, subject to configuration review and custom order lead time.
