Merck Millipore Elix 100 Ultra-Pure Water System
| Origin | France |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | Elix 100 |
| Pricing | Upon Request |
Overview
The Merck Millipore Elix 100 is a high-capacity, integrated water purification system engineered to deliver up to 4,000 L/day of Type II analytical-grade purified water—meeting or exceeding stringent international standards including ASTM D1193, ISO 3696:1987 (Grade 2), BS 3978, USP Purified Water monograph, and EP Purified Water specifications. Designed for central laboratory deployment, the Elix 100 employs a multi-stage purification architecture combining activated carbon prefiltration, dual-wavelength UV oxidation (185/254 nm), continuous electrodeionization (Elix CEDI), and integrated resistivity and TOC monitoring. Unlike batch-based deionization systems, the patented Elix CEDI module enables uninterrupted regeneration of ion-exchange media via direct current, eliminating chemical regeneration cycles and ensuring stable, long-term conductivity performance (< 1 µS/cm at 25 °C) without resin exhaustion. The system operates as a standalone unit or integrates seamlessly into facility-wide water distribution networks—serving as both primary purification source and pretreatment feed for downstream Milli-Q® or Super-Q® ultrapure water systems.
Key Features
- Continuous Electrodeionization (CEDI) technology with integrated DC power supply for real-time, chemical-free regeneration of ion-exchange resins
- Dual-lamp UV chamber (185 nm + 254 nm) for simultaneous organic oxidation and microbial inactivation—critical for low-TOC (< 5 ppb) and low-bacteria (< 1 CFU/mL) output
- Onboard conductivity/resistivity sensor (0.01–18.2 MΩ·cm range) and real-time TOC analyzer (detection limit: ≤3 ppb) with automatic data logging
- Modular, field-replaceable pre-treatment cartridges—including activated carbon, scale inhibitors, and optional softening modules—configured per local feed water quality profiles (e.g., hardness, chlorine, silica)
- Integrated recirculation pump, sanitary loop-compatible ASM (Air Sterile Module), and loop-mounted UV lamp for closed-loop distribution systems
- Touchscreen HMI with configurable alarm thresholds, maintenance scheduling, and audit-trail-enabled event logging compliant with GLP/GMP documentation requirements
Sample Compatibility & Compliance
The Elix 100 accommodates variable municipal and well-water feed sources without mandatory external softening—its adaptive pre-treatment design adjusts to inlet TDS (up to 500 ppm), free chlorine (0.1–2.0 mg/L), and turbidity (< 1 NTU). All wetted materials comply with USP Class VI biocompatibility testing and FDA 21 CFR 177.2420 for food-contact polymers. System validation documentation supports IQ/OQ/PQ protocols aligned with ISO 9001, ISO 13485, and Annex 11 (EU GMP) requirements. Output water conforms to pharmacopeial purified water specifications for pharmaceutical manufacturing (USP , EP 2.2.42), clinical diagnostics (CLSI GP17-A3), and analytical chemistry (ASTM D1193 Type II).
Software & Data Management
The embedded control software provides password-protected user roles (Operator, Technician, Administrator), time-stamped operation logs, and automated calibration reminders. All resistivity, TOC, UV intensity, and flow rate data are timestamped and exportable via USB or Ethernet (Modbus TCP/IP) to LIMS or SCADA platforms. Audit trail functionality records user actions, parameter changes, and alarm events—including who initiated, when, and why—with immutable digital signatures satisfying FDA 21 CFR Part 11 electronic record requirements. Optional remote monitoring via Milli-Q® Connect cloud interface enables real-time status alerts and predictive maintenance analytics.
Applications
- Preparation of microbiological growth media, cell culture buffers, and sterile irrigation solutions
- Feed water for Milli-Q® Integral, Advantage A10, or Biocel® ultrapure systems requiring consistent low-ionic-load input
- Pharmaceutical process water in non-sterile manufacturing (e.g., tablet coating, API synthesis support)
- High-performance liquid chromatography (HPLC) mobile phase preparation and instrument rinsing
- Electrophoresis, ELISA, PCR reagent dilution, and next-generation sequencing sample prep
- Hydroponic and aquaponic research requiring controlled mineral-free nutrient delivery
- Calibration standard preparation for ICP-MS, AAS, and ion chromatography applications
FAQ
What feed water quality is required for optimal Elix 100 performance?
The system accepts municipal tap water with ≤500 ppm TDS, ≤2.0 mg/L free chlorine, and ≤1 NTU turbidity. Pre-treatment cartridge selection is customized during commissioning based on local water analysis.
Can the Elix 100 be connected to an existing lab water distribution loop?
Yes—it supports both pressurized and gravity-fed configurations with optional booster pump, loop UV, ASM, and distributed TOC/resistivity sensors for full-loop monitoring.
How often do consumables require replacement?
Pre-filters: every 6–12 months (based on usage and inlet water quality); CEDI stack lifetime: ≥3 years; UV lamps: 12-month replacement interval (validated by intensity monitoring).
Is the system compliant with FDA 21 CFR Part 11 for electronic records?
Yes—audit trail, electronic signatures, and data integrity controls are enabled by default and validated per internal SOPs aligned with Part 11 Annex A guidance.
Does the Elix 100 provide documentation for regulatory audits?
Full IQ/OQ documentation packages—including factory test reports, calibration certificates, material compliance statements, and cybersecurity validation summaries—are available upon request.
