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METTLER TOLEDO MA155DU Analytical Balance

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Brand METTLER TOLEDO
Origin Shanghai, China
Model MA155DU Analytical Balance
Readability 0.1 mg
Capacity 155 g
Calibration Internal automatic calibration with built-in test weight
Display High-contrast LCD with graphical user interface
Interface USB-A, RS232
Compliance ISO/IEC 17025, GLP/GMP-ready, FDA 21 CFR Part 11 compatible (with optional software)

Overview

The METTLER TOLEDO MA155DU Analytical Balance is a precision laboratory instrument engineered for routine analytical weighing tasks in quality control, research, and production environments. Operating on electromagnetic force compensation (EMFC) technology, it delivers high reproducibility and long-term stability under variable environmental conditions. With a maximum capacity of 155 g and readability of 0.1 mg, the MA155DU meets the performance requirements of ISO 9001-certified laboratories and supports traceable measurement workflows compliant with ISO/IEC 17025. Its robust mechanical design—featuring a monolithic weighing cell, draft shield-compatible housing, and corrosion-resistant stainless-steel pan—ensures consistent metrological performance across shifts and operators. The balance is manufactured in METTLER TOLEDO’s Shanghai facility under the same global quality management system applied to all METTLER TOLEDO analytical instruments.

Key Features

  • Electromagnetic force compensation (EMFC) transducer delivering high linearity and minimal drift over time
  • Internal automatic calibration with integrated test weight, triggered manually or scheduled via timer
  • High-contrast graphical LCD display with intuitive icon-based navigation and real-time on-screen guidance for each weighing step
  • Touch-sensitive front-panel keys with haptic feedback—designed for gloved operation and resistant to repeated cleaning with ethanol or isopropanol
  • Draft shield compatibility (optional accessory) for stable measurements in non-climate-controlled labs
  • Auto-zero tracking and dynamic temperature compensation algorithms to mitigate ambient thermal influence
  • IP54-rated enclosure for protection against dust ingress and incidental liquid splashes during routine lab use

Sample Compatibility & Compliance

The MA155DU accommodates standard sample containers—including weighing boats, crucibles, vials, and filter papers—within its 155 g capacity range. Its open-top design and low-profile weighing chamber allow seamless integration with automated dispensing systems and robotic sample handlers. From a regulatory standpoint, the balance supports Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP) documentation requirements through configurable audit trail logging (when used with METTLER TOLEDO LabX software). It complies with international standards including OIML R76, ASTM E898, and USP , and provides full traceability when paired with certified calibration weights and documented uncertainty budgets. All firmware versions undergo rigorous validation per IEC 62304, ensuring compliance readiness for regulated pharmaceutical and medical device manufacturing.

Software & Data Management

Data integrity is maintained through dual-channel connectivity: RS232 enables direct serial output to legacy label printers and LIMS terminals, while USB-A supports plug-and-play connection to Windows-based PCs and USB flash drives for standalone data export. The balance natively supports ASCII and SICS protocols for seamless integration into enterprise systems. When connected to METTLER TOLEDO LabX software (sold separately), the MA155DU gains full 21 CFR Part 11 compliance—including electronic signatures, role-based access control, and immutable audit trails. LabX also enables method-driven workflows, automatic report generation (PDF/CSV), and centralized instrument monitoring across multi-site deployments.

Applications

  • Quantitative formulation in pharmaceutical R&D and QC labs (e.g., active pharmaceutical ingredient (API) dosing, excipient blending)
  • Gravimetric analysis for titration standard preparation and reference material certification
  • Moisture content determination via loss-on-drying (LOD) when interfaced with a halogen moisture analyzer
  • Sample preparation for ICP-MS, HPLC, and GC-MS workflows requiring sub-milligram mass accuracy
  • Educational laboratories where intuitive operation and durability are critical for student training
  • Environmental testing labs performing filter weighing for particulate matter (PM2.5/PM10) analysis

FAQ

What is the recommended recalibration frequency for the MA155DU in a GLP environment?
Calibration intervals must be risk-assessed per ISO/IEC 17025 Clause 6.5; typical practice includes daily zero checks, weekly internal calibration, and annual external verification using accredited weights.
Does the MA155DU support direct connection to an ERP or SAP system?
Yes—via RS232 or USB-to-serial adapters, the balance can feed data into middleware platforms (e.g., LabVantage, Thermo Fisher SampleManager) that interface with ERP/SAP through standardized APIs.
Can the MA155DU be used without LabX software and still meet FDA 21 CFR Part 11 requirements?
No—standalone operation provides no electronic signature, audit trail, or access control; Part 11 compliance requires validated software such as LabX with configured user roles and encrypted database logging.
Is the weighing pan removable for cleaning?
Yes—the stainless-steel pan is tool-free detachable and autoclavable up to 121°C for sterile applications in biopharma settings.
What environmental conditions affect repeatability, and how does the MA155DU compensate?
Ambient temperature fluctuations and air currents are primary variables; the MA155DU employs real-time thermal drift compensation and auto-zero stabilization to maintain ≤0.0002 g repeatability at 23°C ±1.5°C and <60% RH.

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