METTLER TOLEDO MR104 Analytical Balance
| Brand | METTLER TOLEDO |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Authorized Distributor |
| Product Origin | Domestic (China) |
| Model | MR104 Analytical Balance |
| Pricing | Available Upon Request |
Overview
The METTLER TOLEDO MR104 Analytical Balance is a high-precision mass measurement instrument engineered for reproducible, traceable weighing in regulated and non-regulated laboratory and industrial environments. Operating on electromagnetic force compensation (EMFC) principle, the MR104 delivers stable, drift-free readings with a readability of 0.1 mg and a maximum capacity of 104 g — meeting the fundamental performance requirements for analytical weighing defined in USP , ISO/IEC 17025, and ASTM E898. Its monolithic aluminum alloy weighing cell, combined with active temperature compensation and internal mass calibration technology, ensures long-term stability under variable ambient conditions — including fluctuations in temperature, humidity, and air currents common in shared labs or production-floor settings.
Key Features
- Robust all-metal housing with IP54-rated protection against dust and liquid splashes — validated for operation in demanding environments including QC labs, pilot plants, and manufacturing cleanrooms.
- Integrated QuickLock draft shield system: tool-free, one-step removal for rapid access; fully autoclavable and dishwasher-safe components (draft shield panels, weighing pan, drip tray).
- Automatic internal calibration (FACT — Fully Automatic Calibration Technology) with temperature-triggered recalibration to maintain accuracy across diurnal thermal cycles.
- Guided leveling system with integrated bubble level and motorized foot adjustment — reduces setup time and eliminates operator-induced leveling errors.
- Overload protection mechanism safeguards the load cell from mechanical shock, accidental pan drops, and static overloading up to 200% of nominal capacity.
- Ergonomic design: smooth, rounded edges; seamless surfaces; no crevices — compliant with cleaning validation protocols per FDA CGMP Annex 11 and EU GMP Annex 15.
Sample Compatibility & Compliance
The MR104 supports a broad range of sample types — from powders and granules to volatile solvents and hygroscopic materials — when used with appropriate draft shields and static-dissipative accessories. Its weighing chamber accommodates standard 90 mm diameter pans and optional anti-static ionizers. The balance complies with international regulatory frameworks including ISO 9001:2015 (quality management), ISO/IEC 17025:2017 (testing and calibration laboratories), and meets essential requirements of the EU Measuring Instruments Directive (MID) for Class I accuracy. Optional user administration modules support role-based access control aligned with 21 CFR Part 11 electronic record/electronic signature (ER/ES) requirements.
Software & Data Management
The MR104 natively supports METTLER TOLEDO’s MT-SICS (Standard Interface Command Set), enabling seamless bidirectional communication with LIMS, MES, and PLC systems via RS232, USB, or Ethernet interfaces. It is compatible with LabX® software for centralized instrument management, audit-trail-enabled data capture, and automated report generation — fulfilling ALCOA+ (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available) data integrity principles. All weight data, calibration logs, and user actions are timestamped and stored with full traceability, supporting GLP and GMP audit readiness.
Applications
- Quantitative preparation of reference standards and working solutions in pharmaceutical QC laboratories.
- Weighing of active pharmaceutical ingredients (APIs) during formulation development and batch release testing.
- Gravimetric analysis in academic and industrial chemistry labs requiring high repeatability (≤ 0.005% RSD at full capacity).
- In-process control (IPC) weighing in food, chemical, and cosmetics manufacturing where hygiene and rapid cleaning are critical.
- Calibration of secondary standards and transfer standards in metrology service labs operating under ISO/IEC 17025 accreditation.
FAQ
What is the readability and maximum capacity of the MR104 Analytical Balance?
The MR104 offers 0.1 mg readability with a 104 g maximum capacity.
Does the MR104 support internal calibration? Is external calibration required?
Yes — it features FACT (Fully Automatic Calibration Technology) with built-in reference masses; external calibration is only required for periodic verification or after relocation.
Can the MR104 be integrated into a networked laboratory environment?
Yes — via RS232, USB Device/Host, or Ethernet (with optional interface module), supporting MT-SICS and LabX connectivity.
Is the draft shield dishwasher-safe?
Yes — all QuickLock draft shield components, including glass panels and the stainless-steel weighing pan, are certified for dishwasher cleaning per IEC 60529 IP65 test conditions.
How does the MR104 ensure compliance with 21 CFR Part 11?
When paired with LabX software and configured with user authentication, electronic signatures, and audit-trail logging, it satisfies electronic record and signature requirements for regulated environments.
