Milli-Q® IPAKKIT00 Purification Cartridge Kit for Non-Elix Feed Water
| Brand | Milli-Q |
|---|---|
| Origin | France |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Import Status | Imported |
| Model | IPAKKIT00 |
| Purity Grade | ASTM Type I / ISO 3696 Grade 1 / CLSI EP25-A2 Compliant |
| Resistivity | 18.2 MΩ·cm @ 25 °C |
| Heavy Metals & Soluble Silica | <0.1 ppb |
| Total Organic Carbon (TOC) | <5 ppb |
| Microbial Count | <0.001 CFU/mL |
| Endotoxin | <0.001 EU/mL |
| Particles (>0.1 µm) | <1 particles/mL |
Overview
The Milli-Q® IPAKKIT00 Purification Cartridge Kit is a purpose-engineered consumable assembly designed exclusively for Milli-Q® ultrapure water systems operating with non-Elix feed water sources—such as reverse osmosis (RO) permeate, deionized (DI) water, or distilled water from third-party pretreatment units. Unlike standard Elix-compatible configurations, this kit integrates two complementary high-performance purification stages: the IPAK Meta® cartridge and the IPAK Quanta® cartridge. The system leverages dual-media ion exchange architecture—combining Jetpore® mixed-bed resin with IQo™ ion exchange media—to achieve trace-level removal of residual ions, organic contaminants, and particulates. This configuration ensures consistent delivery of ASTM Type I ultrapure water meeting stringent requirements for analytical chemistry, molecular biology, cell culture, and semiconductor-grade rinsing applications.
Key Features
- Two-stage modular design: IPAK Meta® (pre-purification) and IPAK Quanta® (polishing) cartridges installed in series to maximize contaminant removal efficiency and service life.
- IQo™ ion exchange media featuring sub-50 µm functional beads—delivering enhanced mass transfer kinetics and 33% reduced column volume versus prior-generation Milli-Q® cartridges without compromising capacity.
- High-density synthetic activated carbon granules engineered for adsorptive removal of low-molecular-weight organics, chlorine, chloramines, and THMs down to <5 ppb TOC.
- Endotoxin-retentive membrane integrated into the IPAK Quanta® stage, validated to reduce endotoxin levels to <0.001 EU/mL—critical for sensitive mammalian cell culture and immunological assays.
- Pre-assembled, factory-sealed, and individually tested for resistivity, TOC, and microbial performance; each kit includes full QC documentation traceable to ISO/IEC 17025-accredited calibration protocols.
Sample Compatibility & Compliance
The IPAKKIT00 is validated for use with Milli-Q® Advantage A10, Integral 3, and RiOS™ 5/10/20 systems when supplied with feed water meeting minimum specifications: conductivity ≤5 µS/cm, TOC ≤500 ppb, and bacterial count ≤100 CFU/mL. It is not compatible with Elix-based feed water circuits due to differential pressure and flow rate constraints. All performance claims are verified per ISO 3696:1987, ASTM D1193-20, and CLSI EP25-A2 guidelines. The kit supports GLP/GMP workflows through full audit trail compatibility with Milli-Q® Connect cloud-based monitoring software and satisfies data integrity requirements under FDA 21 CFR Part 11 when deployed with enabled electronic signature modules.
Software & Data Management
When used with Milli-Q® systems equipped with SmartConnect™ hardware, the IPAKKIT00 enables real-time cartridge lifecycle tracking—including remaining capacity estimation, usage time logging, and predictive replacement alerts. All purification metrics (resistivity, TOC, temperature, flow rate) are timestamped and exportable in CSV or PDF format via Milli-Q® Connect web portal. Integrated RFID tagging ensures automatic recognition upon installation, eliminating manual configuration errors and supporting automated SOP execution during routine water quality verification.
Applications
- Preparation of HPLC and UHPLC mobile phases requiring ultra-low ionic background and minimal UV-absorbing organics.
- Formulation of electrophysiology buffers and patch-clamp solutions where trace cation interference must be eliminated.
- Rinsing of photomasks and wafers in microfabrication cleanrooms (ISO Class 1–3 environments).
- Generation of reagent-grade water for qPCR master mixes, CRISPR-Cas9 editing workflows, and single-cell RNA sequencing library prep.
- Calibration of trace metal analyzers (ICP-MS, GF-AAS) demanding sub-ppt contamination control.
FAQ
Can the IPAKKIT00 be used with Elix-pre-treated feed water?
No—this kit is specifically validated for non-Elix feed sources only. Using it with Elix-derived water may cause premature exhaustion and invalidates performance warranties.
What is the recommended maximum feed water conductivity?
Feed water conductivity must not exceed 5 µS/cm at 25 °C. Higher values require upstream RO or EDI polishing before IPAKKIT00 installation.
How often should the cartridges be replaced?
Typical service life ranges from 6 to 12 months depending on daily water consumption and feed water quality; real-time monitoring via SmartConnect™ provides precise endpoint detection.
Does the kit include validation documentation?
Yes—each sealed package contains a Certificate of Conformance listing batch-specific test results for resistivity, TOC, endotoxin, and particle count, compliant with ISO/IEC 17025 reporting standards.
Is the IPAKKIT00 compatible with third-party water systems?
No—it is a proprietary Milli-Q® consumable and requires mechanical, electrical, and firmware integration with designated Milli-Q® platforms only.
