Nippon Scientific SP-D-2502 Dual-Piston Constant Flow Pump
| Brand | Nippon Scientific |
|---|---|
| Origin | Japan |
| Model | SP-D-2502 |
| Flow Rate Range | 0.15–1.5 mL/min (50 Hz) / 0.18–1.8 mL/min (60 Hz) |
| Max Delivery Pressure | 10 MPa |
| Wetted Materials | SUS316, Sapphire, Ruby, Ceramics, PTFE |
| Dimensions | 250 × 190 × 126 mm (W×D×H) |
| Weight | 3.5 kg |
| Power Supply | AC 100 V, 50/60 Hz |
Overview
The Nippon Scientific SP-D-2502 is a dual-piston constant flow pump engineered for high-precision, pulse-free liquid delivery in analytical and preparative laboratory applications. Based on positive displacement principle with synchronized dual-piston actuation, it eliminates flow pulsation inherent in single-piston designs—ensuring stable volumetric delivery critical for HPLC, SFC, solvent delivery in reaction monitoring, and microfluidic interfacing. Its robust mechanical architecture integrates precision-machined stainless steel (SUS316) pump heads, sapphire-ruby check valves, and chemically inert ceramic/PTFE seals, enabling reliable operation across aggressive solvents including acetonitrile, THF, chlorinated hydrocarbons, and dilute acids/bases. Designed and manufactured in Japan under stringent JIS Q 9001-compliant quality control, the SP-D-2502 meets international expectations for long-term repeatability (±0.5% RSD over 24 h), pressure stability (< ±0.1 MPa drift at 8 MPa), and low maintenance intervals.
Key Features
- Dual-piston synchronization mechanism delivering continuous, pulse-free flow with <0.3% flow ripple (measured per ISO 5199 Annex B)
- Stroke-length-based flow adjustment: precise, mechanical, and calibration-free—no software or external controllers required
- Two independent fluid paths support parallel delivery, gradient mixing, or solvent switching without hardware modification
- Modular wetted material configuration: standard SUS316/sapphire/ruby/ceramic/PTFE; optional PEEK-head variants (SP-D-2502P) available for enhanced chemical resistance
- Compact footprint (250 × 190 × 126 mm) optimized for benchtop integration in fume hoods, gloveboxes, or automated workstations
- Front-panel LED display with real-time flow rate indication and pressure warning threshold (configurable up to 10 MPa)
Sample Compatibility & Compliance
The SP-D-2502 is validated for use with aqueous buffers, organic solvents, and low-viscosity polymer solutions (≤50 mPa·s). Its wetted path complies with USP Class VI biocompatibility requirements for PTFE and PEEK components. All models conform to IEC 61010-1:2010 for laboratory electrical safety and meet CE marking requirements under the Low Voltage Directive (2014/35/EU) and EMC Directive (2014/30/EU). For regulated environments, the pump supports audit-ready operation when integrated with GLP/GMP-compliant data acquisition systems—its analog output (0–5 V DC) enables traceable flow/pressure logging aligned with FDA 21 CFR Part 11 principles when paired with compliant software.
Software & Data Management
While fully functional as a standalone instrument, the SP-D-2502 offers optional analog interface (0–5 V DC) for flow and pressure signal output, compatible with LabVIEW, MATLAB, or third-party SCADA platforms. No proprietary software is required; however, Nippon Scientific provides a reference Python API (open-source, MIT licensed) for remote parameter setting and status polling via RS-232 (optional adapter kit). All firmware updates are delivered as signed binary packages with SHA-256 checksum verification. Internal non-volatile memory retains last-used stroke position and pressure limit settings across power cycles—supporting continuity in unattended overnight runs.
Applications
- HPLC and UHPLC mobile phase delivery where low pulsatility improves baseline stability and column longevity
- Supercritical fluid chromatography (SFC) with CO₂/co-solvent systems requiring precise dual-stream metering
- Controlled reagent addition in catalytic reaction screening and flow chemistry reactors (e.g., Corning AFR, Vapourtec R-Series)
- Calibration standard delivery in gravimetric flow verification setups per ISO 4064-2
- Sample introduction in ICP-MS and LC-MS systems demanding ultra-low carryover and consistent nebulization
- Microscale solvent extraction and solid-phase extraction (SPE) manifold automation
FAQ
What is the minimum programmable flow resolution?
The stroke-length adjustment mechanism provides continuous mechanical control; typical user resolution is ~0.02 mL/min, limited only by vernier scale readability.
Can the SP-D-2502 be used with viscous fluids above 100 mPa·s?
Not recommended—maximum specified viscosity is 50 mPa·s at 25°C. Higher viscosities increase wear on ruby/sapphire valves and reduce pressure stability.
Is the pump compatible with corrosive halogenated solvents such as chloroform or carbon tetrachloride?
Yes, when configured with PTFE and sapphire-wetted components (standard on SP-D-2502); avoid prolonged exposure to undiluted brominated solvents.
Does the unit include pressure relief protection?
Yes—a factory-set mechanical pressure relief valve activates at 10.5 ± 0.3 MPa, venting excess pressure safely to waste.
What maintenance schedule is recommended for routine operation?
Valve inspection every 500 hours; piston seal replacement every 2,000 hours under continuous use at ≤7 MPa and ambient temperature.
