Norl HPLC UV Detector D205
| Origin | Canada |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported Instrument |
| Model | D205 |
| Condition | Refurbished (4–5 years operational history) |
| Warranty | 6 months |
| Product Category | UV-Vis Absorbance Detector for HPLC Systems |
| Compliance | Fully tested and calibrated per ISO/IEC 17025-aligned refurbishment protocol |
Overview
The Norl D205 is a high-stability, dual-beam UV-Vis absorbance detector engineered for integration into high-performance liquid chromatography (HPLC) systems. Designed with a deuterium lamp source and precision optical path architecture, it delivers reliable photometric detection across the 190–700 nm wavelength range—enabling quantitative and qualitative analysis of analytes based on Beer–Lambert law absorption characteristics. This refurbished unit has undergone full functional validation at SpectraLab Scientific’s certified refurbishment facility, including baseline noise assessment (< ±0.5 × 10⁻⁵ AU), drift evaluation (< 1 × 10⁻⁴ AU/h), and wavelength accuracy verification (±1 nm traceable to NIST SRM 2034). Its modular design supports seamless coupling with standard HPLC modules (e.g., pumps, autosamplers, column ovens) via industry-standard analog and digital I/O interfaces.
Key Features
- Dual-beam optical system with real-time reference compensation for enhanced signal stability
- Deuterium lamp with typical lifetime >1,500 hours; lamp status and usage time logged in firmware
- Programmable wavelength scanning (single or multi-wavelength mode) with 1 nm resolution
- Analog output (0–1 V or 0–5 V, switchable) and RS-232/USB communication for direct instrument control
- Detachable flow cell (10 mm path length, 8 µL volume) compatible with stainless steel or PEEK capillary connections
- Front-panel keypad and LCD display for standalone operation; no PC dependency required for basic acquisition
- Refurbishment includes replacement of critical wear components: lamp housing gaskets, optical window seals, and detector electronics thermal management elements
Sample Compatibility & Compliance
The D205 is compatible with common reversed-phase, normal-phase, and ion-exchange HPLC mobile phases—including aqueous buffers (e.g., phosphate, acetate), organic modifiers (acetonitrile, methanol), and low-concentration TFA or formic acid solutions. It meets mechanical and electrical safety requirements per IEC 61010-1:2010 and electromagnetic compatibility standards EN 61326-1:2013. While not supplied with FDA 21 CFR Part 11-compliant software out-of-the-box, its analog/digital outputs are fully compatible with validated third-party chromatography data systems (CDS) that support audit trail, electronic signature, and user access control—enabling deployment in GLP and GMP environments when integrated into a qualified workflow.
Software & Data Management
The detector operates independently of proprietary software but interfaces seamlessly with widely adopted CDS platforms including Chromeleon™ (Thermo Fisher), Empower™ (Waters), and OpenLab CDS (Agilent). Raw absorbance signals are acquired as analog voltage outputs synchronized with pump pressure and column temperature triggers—ensuring temporal alignment during gradient elution. SpectraLab provides calibration certificates documenting post-refurbishment performance metrics, including spectral bandwidth ( 0.999 over 0–2 AU range), and response time (< 1 s to 90% of final value). All units ship with firmware version 3.2.1, supporting firmware updates via USB flash drive.
Applications
- Pharmaceutical QC testing: assay of active pharmaceutical ingredients (APIs), related substances, and dissolution profiling per USP and EP 2.2.46
- Environmental analysis: detection of phenolic compounds, pesticides, and polycyclic aromatic hydrocarbons (PAHs) in water extracts
- Food & beverage quality control: quantification of preservatives (e.g., benzoic acid, sorbic acid), antioxidants (BHA/BHT), and colorants
- Academic research: method development for LC-UV hyphenated workflows, kinetic studies, and stability-indicating assays
- Contract laboratories: cost-effective alternative to new-entry detectors for routine compliance testing under ISO/IEC 17025 accreditation
FAQ
Is the D205 compatible with my existing HPLC system?
Yes—the D205 features universal analog input/output (0–1 V or 0–5 V) and RS-232/USB connectivity, enabling interoperability with major OEM HPLC platforms (Waters, Shimadzu, Agilent, Thermo Fisher) and open-architecture systems.
What documentation is included with the refurbished unit?
Each unit ships with a Certificate of Refurbishment, full calibration report (including noise, drift, wavelength accuracy, and linearity data), firmware version log, and electrical safety test record—all traceable to internal QA procedures aligned with ISO/IEC 17025 principles.
Can the detector be used in regulated environments (e.g., pharmaceutical manufacturing)?
Yes—when integrated into a validated chromatography data system with appropriate user access controls, audit trails, and electronic signatures, the D205 satisfies technical requirements for use in GMP and GLP applications per ICH Q2(R2) and FDA guidance.
Does the 6-month warranty cover lamp replacement?
The warranty covers all electronic, optical, and mechanical components excluding consumables; the deuterium lamp is considered a consumable and is not covered, though its remaining operational life is verified and documented prior to shipment.
How is “refurbished” defined in this context?
Refurbishment includes full disassembly, cleaning, optical alignment verification, replacement of aged seals and thermal interface materials, functional testing against original factory specifications, and recalibration using traceable standards—performed by ISO 9001-certified technicians.
