PerkinElmer Altus A10 HPLC System (Refurbished)
| Brand | PerkinElmer |
|---|---|
| Origin | USA |
| Model | Altus HPLC A10 |
| Instrument Age | 4–5 years in service (7-year total design life) |
| Warranty | 6 months |
| Configuration | PDA Detector, Solvent & Sample Module, Column Module, LabSolutions-compatible PC, tubing and interconnects included |
| Compliance | Fully tested per ASTM E2653-22 (Standard Guide for Verification of HPLC Systems) |
| Software Environment | Compatible with Waters Empower 3 (via standard ASCII/CSV export) and PerkinElmer’s legacy Turbochrom software |
Overview
The PerkinElmer Altus A10 HPLC System is a modular, high-reliability liquid chromatography platform engineered for routine quantitative and qualitative analysis in regulated and non-regulated laboratory environments. Built on a low-diffusion, integrated flow-path architecture, the system minimizes band broadening and ensures consistent retention time stability—critical for method transfer, long-term method validation, and compliance with pharmacopeial requirements (USP , EP 2.2.46). The Altus A10 employs dual-piston reciprocating pumps with active solvent compressibility compensation, delivering flow precision ≤0.1% RSD across 0.05–5.0 mL/min and pressure stability up to 400 bar. Its PDA detector features a 1024-element diode array with 190–800 nm spectral range, 1 nm resolution, and real-time peak purity assessment via spectral overlay and library matching. Designed for operational continuity, the system supports walk-away operation with up to 120-position autosampler capacity (via optional tray expansion), gradient delay volume < 600 µL, and column oven temperature control from ambient +5°C to 80°C (±0.2°C).
Key Features
- Modular architecture: Independent solvent delivery, sample introduction, and column management modules enable flexible configuration and simplified maintenance.
- Low-dead-volume fluidic path: Integrated stainless-steel capillaries and zero-dead-volume fittings reduce extra-column dispersion, preserving chromatographic efficiency (theoretical plates >100,000 for 150 mm × 4.6 mm, 5 µm columns).
- PDA-based detection: Simultaneous multi-wavelength acquisition supports peak identification, purity evaluation, and method development without re-injection.
- Tool-free service design: Pump heads, purge valves, and detector flow cells are accessible without specialized tools—reducing downtime during routine maintenance or seal replacement.
- Regulatory-ready operation: System logs all hardware events, method parameters, and user actions; audit trail functionality meets FDA 21 CFR Part 11 requirements when paired with validated Empower 3 or Turbochrom software configurations.
Sample Compatibility & Compliance
The Altus A10 accommodates reversed-phase, normal-phase, ion-exchange, and size-exclusion chromatography applications using standard 4.6 mm ID analytical columns (up to 250 mm length) and compatible guard cartridges. It accepts aqueous-organic mobile phases (e.g., water/acetonitrile, water/methanol), buffers (e.g., phosphate, acetate), and volatile additives (e.g., formic acid, ammonium acetate) within pH 1.5–12.0. All refurbished units undergo full functional verification per ASTM E2653-22, including pump flow accuracy, gradient composition linearity, detector wavelength accuracy (NIST-traceable holmium oxide filter), and baseline noise specification (< ±2.5 × 10⁻⁵ AU at 254 nm). Each system ships with IQ/OQ documentation templates aligned with ISO/IEC 17025 and GLP laboratory practices.
Software & Data Management
The system operates natively with PerkinElmer Turbochrom v7.x for instrument control and basic data review. For full GxP compliance—including electronic signatures, role-based access control, and secure audit trails—the platform integrates seamlessly with Waters Empower 3 CDS (v3.7+), leveraging standard .CDF and .RAW file formats. Data export supports CSV, ASCII, and PDF reporting for LIMS ingestion. All refurbished units include validated software installation media and license transfer documentation where permitted under original End User License Agreement (EULA) terms. SpectraLab Scientific provides post-delivery software configuration support and IQ/OQ protocol execution assistance.
Applications
- Pharmaceutical quality control: Assay, related substances, and dissolution testing per USP monographs.
- Food and beverage safety: Pesticide residue screening, mycotoxin quantification, and vitamin profiling.
- Environmental analysis: PAHs, PCBs, and phenolic compounds in water and soil extracts.
- Academic and contract research: Method development, stability-indicating assays, and preparative fraction collection (with optional fraction collector interface).
FAQ
Is this unit eligible for extended warranty or service contracts?
Yes—SpectraLab Scientific offers optional 12- and 24-month extended service agreements covering parts, labor, and preventive maintenance visits.
Can the system be upgraded to support UHPLC conditions?
No—the Altus A10 is rated for maximum operating pressure of 400 bar and is not compatible with sub-2 µm particles or UHPLC-grade instrumentation requirements.
What documentation is provided with the refurbished system?
Each unit ships with a Certificate of Conformance, full test report (including pump linearity, detector noise, and retention time reproducibility data), IQ/OQ checklist, and traceable calibration records.
Is remote diagnostics supported?
Yes—when connected to a local network, the system supports secure remote troubleshooting via TeamViewer-assisted sessions with SpectraLab’s application engineers.
Does the system include a validated method package?
No—method validation is lab-specific and must be performed in-house per ICH Q2(R2); however, we provide method transfer templates and chromatographic parameter benchmarks for common USP assays.
