Precisa XS365M Analytical Balance

Overview

The Precisa XS365M Analytical Balance is a high-precision laboratory weighing instrument engineered for routine analytical and quality control applications requiring reliable 1 mg readability and robust metrological performance. Based on electromagnetic force compensation (EMFC) technology, the XS365M delivers stable, drift-resistant measurements across its full 365 g capacity. Its design conforms to international weighing standards—including OIML R76 and ISO/IEC 17025—ensuring traceable accuracy under controlled environmental conditions (0–40 °C, non-condensing). The balance integrates a precision load cell with temperature-compensated feedback circuitry, minimizing sensitivity drift to ±3 ppm/°C within the 10–30 °C range—a critical specification for laboratories operating in variable ambient conditions. With a linearity error of ±1.5 mg and reproducibility ≤1 mg, the XS365M meets the repeatability requirements for pharmacopeial testing (e.g., USP ), raw material verification, and formulation checks in regulated environments.

Key Features

• Fluorescent display option ensures high-contrast, glare-free readability from multiple viewing angles—even under low-light or overhead illumination typical in fume hoods or glove boxes.
• Three-step stability adjustment allows users to optimize response time versus noise rejection: “Fast” (1 s), “Medium” (1.5 s), or “Slow” (2 s), accommodating viscous samples, draft-prone workspaces, or vibration-sensitive installations.
• Internal self-calibration and user-defined external calibration routines support compliance with ISO 9001 and GLP documentation requirements; optional calibration log export enables audit-ready traceability.
• Auto-power-on upon mains restoration eliminates manual restart after power interruptions—critical for unattended overnight weighing protocols.
• Programmable auto-off (selectable 5/15/30/60 min idle timeout) conserves energy without compromising data integrity; all active settings and zero point are retained in non-volatile memory during shutdown.
• Chromium-nickel steel weighing pan (135 × 135 mm) provides corrosion resistance and mechanical durability for repeated solvent exposure and abrasive sample handling.

Sample Compatibility & Compliance

The XS365M accommodates standard analytical vials, crucibles, weighing boats, and small-volume containers within its 60 mm draft shield height. Its tare range matches the full capacity (365 g), enabling direct subtraction of container mass for net weight determination—essential for loss-on-drying (LOD), ash content, and gravimetric titration workflows. The balance complies with electromagnetic compatibility (EMC) directives (IEC 61326-1) and safety standards (IEC 61010-1), making it suitable for installation in Class A/B cleanrooms and ISO 14644-compliant facilities. While not intrinsically rated for hazardous locations, its low power consumption (6 VA) and thermal management support continuous operation in temperature-stabilized QC labs aligned with FDA 21 CFR Part 11 Annex 11 expectations for electronic record integrity.

Software & Data Management

The XS365M supports RS232 and optional USB interfaces for seamless integration with LIMS, ELN, and statistical process control (SPC) platforms. ASCII-formatted output includes timestamp, gross/net/tare values, stability status, and calibration event flags—enabling automated parsing into Excel, Minitab, or custom SQL databases. Optional PC software (Precisa BalanceLink™) provides real-time graphing, GMP-compliant audit trails (user ID, action, timestamp), and configurable PDF report generation per batch or sample ID. All data transfers adhere to ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available), satisfying internal QA audits and external regulatory inspections.

Applications

• Pharmaceutical: Active pharmaceutical ingredient (API) dispensing, reference standard preparation, and dissolution test sample weighing per USP .
• Chemical R&D: Stoichiometric reagent dosing, catalyst loading, and polymerization initiator quantification.
• Food & Agriculture: Moisture analysis (AOAC 950.46), ash residue determination (AOAC 942.05), and nutrient labeling compliance checks.
• Academic Research: Teaching labs requiring ISO/IEC 17025-aligned instrumentation for undergraduate analytical chemistry curricula.
• Environmental Testing: Filter weighing for total suspended solids (TSS) and particulate matter (PM₁₀/PM_2.5) analysis per EPA Method 160.1.

FAQ

Does the XS365M support internal motorized calibration?
No—the XS365M relies on external calibration weights; it does not include an integrated motorized calibrator. However, its programmable calibration sequence supports multi-point verification using NIST-traceable masses.
Is the fluorescent display standard or optional?
The fluorescent display is an optional configuration; standard units ship with LCD. Fluorescent variants are recommended for environments with inconsistent ambient lighting or where parallax-free reading is required.
Can the balance be connected to a networked lab system?
Yes—via RS232 serial interface (standard) or USB-to-serial adapter (optional); Ethernet or Wi-Fi connectivity requires external gateway hardware and is not natively supported.
What is the warranty coverage period?
Precisa provides a 24-month limited warranty covering parts and labor for defects in materials and workmanship under normal laboratory use.
Is the XS365M compliant with FDA 21 CFR Part 11?
The hardware itself is Part 11–capable when paired with validated software (e.g., BalanceLink™ with electronic signature module); standalone operation does not fulfill full electronic record requirements without procedural controls and system validation.