Qiangle LSHZ-300D Intelligent Cryogenic Water-Bath Orbital Shaker
| Origin | Jiangsu, China |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Product Origin | Domestic (China) |
| Model | LSHZ-300D |
| Price | USD 2,650 (approx.) |
Overview
The Qiangle LSHZ-300D Intelligent Cryogenic Water-Bath Orbital Shaker is an engineered platform for precise temperature-controlled agitation of biological and biochemical samples in aqueous environments. Designed around a circulating water-jacketed bath system with integrated Peltier-based cooling and PID-regulated heating, it maintains stable thermal conditions from −10 °C to 60 °C—enabling low-temperature enzymatic assays, cold-sensitive cell culture maintenance, and cryo-stabilized protein solubilization protocols. Its orbital shaking mechanism operates at speeds from 30 to 300 rpm with ±1 rpm speed accuracy and ≤±0.5 °C temperature uniformity across the bath volume (30 L capacity), ensuring high reproducibility in kinetic studies, microbial growth monitoring, and immunoassay incubation workflows.
Key Features
- Intelligent microprocessor control with real-time digital display of both setpoint and actual values for temperature and speed
- Circulating water bath with stainless steel chamber and corrosion-resistant interior coating for long-term chemical compatibility
- Peltier thermoelectric cooling module enabling rapid sub-ambient stabilization without external refrigerants or compressors
- Orbital motion drive with adjustable amplitude (20–30 mm) and brushless DC motor for low-vibration, continuous-duty operation
- Programmable timer (1 min to 99 h 59 min) with auto-stop and alarm functions for unattended overnight runs
- Over-temperature and over-speed safety cutoffs compliant with IEC 61010-1 electrical safety standards
- RS-485 communication interface supporting Modbus RTU protocol for integration into centralized lab automation systems
Sample Compatibility & Compliance
The LSHZ-300D accommodates standard laboratory vessels including Erlenmeyer flasks (50–2000 mL), test tubes, microcentrifuge tube racks, and custom-sized sample trays via optional clamping accessories. Its water-bath design ensures uniform thermal transfer to liquid-phase samples—critical for applications requiring minimal thermal gradients, such as DNA hybridization, antibody-antigen binding kinetics, and microbial suspension homogenization. The unit conforms to ISO/IEC 17025 calibration traceability requirements when used with NIST-traceable thermometers and tachometers. It supports GLP-compliant documentation through optional data logging (via external USB logger or SCADA-compatible output), and its operational parameters meet ASTM E2925-21 guidelines for performance verification of laboratory shakers.
Software & Data Management
While the LSHZ-300D operates primarily via its embedded front-panel controller, its RS-485 port enables bidirectional communication with third-party laboratory information management systems (LIMS) or supervisory control and data acquisition (SCADA) platforms. Users may configure multi-step protocols—including ramp-and-hold temperature profiles and variable-speed sequences—using vendor-provided configuration utilities compatible with Windows-based PCs. Audit trail functionality is available when paired with FDA 21 CFR Part 11–compliant software extensions, providing electronic signatures, user access logs, and immutable parameter change records required for regulated QC/QA environments.
Applications
- Low-temperature enzyme activity assays (e.g., restriction digests at 4 °C)
- Cryopreservation media equilibration and pre-thaw mixing
- Cell suspension culture under hypothermic conditions (e.g., primary hepatocyte maintenance)
- Solubility screening of biopharmaceutical formulations at controlled sub-ambient temperatures
- Antibody labeling reactions requiring strict thermal control to prevent denaturation
- Environmental microbiology: cold-adapted bacterial enrichment in liquid media
- Pharmaceutical stability testing per ICH Q1A(R3) guidance for refrigerated storage conditions
FAQ
What is the minimum operating temperature of the LSHZ-300D?
The unit achieves a stable setpoint down to −10 °C under ambient conditions ≤25 °C and 60% RH, verified per ISO 17025-accredited validation protocols.
Can the shaker accommodate baffled flasks for improved aeration?
Yes—the platform accepts standard 500 mL and 1000 mL baffled Erlenmeyer flasks; optimal aeration is achieved at 150–250 rpm with 25 mm amplitude.
Is the water bath resistant to common organic solvents?
The chamber is constructed from 304 stainless steel with electropolished finish and is compatible with aqueous buffers, ethanol/water mixtures (<30%), and mild detergent solutions; prolonged exposure to acetone, chloroform, or strong acids is not recommended.
Does the device support remote monitoring via Ethernet or Wi-Fi?
No native Ethernet or Wi-Fi interface is included; however, RS-485 output can be bridged to TCP/IP networks using industrial protocol gateways (e.g., Moxa EDS-G205A) for enterprise-level integration.
What calibration documentation is provided?
Each unit ships with a factory calibration certificate covering temperature accuracy (±0.3 °C at 25 °C) and speed accuracy (±0.5 rpm), traceable to national metrology institutes per ISO/IEC 17025 requirements.
