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Rainin Disp-X Manual Bottle Top Dispenser

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Brand Rainin
Origin Switzerland
Type Manual Bottle Top Dispenser
Volume Ranges 0.5–5 mL, 1–10 mL, 2.5–25 mL, 5–50 mL
Compatibility Corrosive and flammable liquids
Sealing Performance Stable across broad temperature and viscosity ranges
Regulatory Context Designed for GLP/GMP-aligned workflows, compliant with ISO 8655-3 for piston-operated liquid handlers

Overview

The Rainin Disp-X Manual Bottle Top Dispenser is an engineered solution for precise, repeatable, and operator-safe volumetric dispensing of liquids directly from reagent bottles. Based on positive-displacement piston technology, the Disp-X operates without reliance on atmospheric pressure or gravity-driven flow—ensuring consistent delivery regardless of liquid density, vapor pressure, or viscosity. This principle enables reliable handling of challenging fluids including organic solvents (e.g., acetone, chloroform), strong acids (e.g., concentrated HCl, HNO₃), bases (e.g., NaOH solutions), and halogenated compounds—without risk of siphoning, dripping, or vapor lock. Its modular, chemically resistant construction—including PTFE, ETFE, and FFKM seals—supports long-term stability in corrosive environments, making it suitable for routine use in analytical, quality control, and regulated production laboratories.

Key Features

  • Four calibrated volume ranges: 0.5–5 mL (DX-50), 1–10 mL (DX-10), 2.5–25 mL (DX-25), and 5–50 mL (DX-50), each factory-adjusted to ±1% accuracy per ISO 8655-3
  • Integrated mechanical safety lock prevents accidental actuation during bottle mounting or transport
  • One-handed, ergonomic plunger mechanism with tactile feedback and smooth stroke resistance—minimizing user fatigue during high-throughput dispensing
  • Chemically inert fluid path: all wetted parts consist of PTFE, ETFE, borosilicate glass, and perfluoroelastomer (FFKM) seals rated for continuous exposure to aggressive media
  • Pressure-relief valve and vented reservoir design eliminate over-pressurization and prevent aerosol generation during rapid dispensing cycles
  • Autoclavable (121°C, 20 min) dispenser head and interchangeable adapters compatible with GL45, GL32, and GL25 bottle neck threads

Sample Compatibility & Compliance

The Disp-X is validated for use with a wide spectrum of laboratory liquids—from low-viscosity solvents (e.g., methanol, acetonitrile) to moderately viscous reagents (up to ~500 mPa·s at 20°C), including aqueous buffers, enzyme solutions, and dye-labeled probes. It meets material compatibility requirements defined in ASTM D471 for elastomer resistance and conforms to ISO 8655-3:2022 for calibration, accuracy, and repeatability of manual piston-type dispensers. In regulated environments, its traceable calibration documentation supports compliance with FDA 21 CFR Part 11 (when paired with electronic logbooks), EU Annex 11, and ICH Q7 quality systems. The absence of electronic components eliminates electromagnetic interference concerns in sensitive instrumentation areas.

Software & Data Management

As a fully manual, non-electronic device, the Disp-X requires no firmware, drivers, or software integration. All operational parameters—including volume setting, stroke count, and maintenance history—are recorded manually in laboratory notebooks or LIMS-compatible log templates. Calibration certificates (traceable to NIST standards) are provided with each unit and include as-found/as-left data, uncertainty budgets, and technician signatures. For labs implementing digital SOPs, Rainin provides editable PDF protocols aligned with ISO/IEC 17025 documentation frameworks, supporting audit readiness for GLP and GMP inspections.

Applications

  • Preparation of standard curves and calibration standards in HPLC, GC, and ICP-MS sample workflows
  • Accurate dilution of cytotoxic drugs and reference standards in pharmaceutical QC release testing
  • Dosing of hazardous reagents (e.g., osmium tetroxide, hydrazine derivatives) under fume hood conditions with minimized exposure risk
  • Reagent distribution in ELISA, PCR setup, and cell culture media preparation where sterility and consistency are critical
  • Forensic toxicology labs handling volatile organic compounds (VOCs) and controlled substances requiring chain-of-custody integrity

FAQ

Is the Disp-X compatible with hydrofluoric acid (HF)?

Yes—when equipped with optional FFKM seals and quartz-glass cylinder, the Disp-X supports intermittent use with ≤40% HF solutions. Full compatibility documentation is available upon request.
Can volume settings be locked to prevent accidental changes?

The DX-10, DX-25, and DX-50 models feature a mechanical volume lock ring that secures the setpoint against unintentional drift during operation.
What maintenance intervals are recommended for routine use?

Rainin recommends visual inspection before each use, weekly cleaning of the piston seal with isopropanol, and full disassembly/cleaning every 3 months—or after handling viscous or particulate-laden solutions.
Does the Disp-X require recalibration after autoclaving?

No. The piston assembly maintains dimensional stability post-autoclave; however, users must verify accuracy using gravimetric verification per ISO 8655-6 before first use following sterilization.
Are replacement parts available globally?

Yes—seal kits, plungers, and adapter assemblies are stocked by Rainin’s authorized distributors in >60 countries, with typical lead time of 3–5 business days.

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