RAININ EDP3 Adjustable Spacing Electronic Multichannel Pipette
| Brand | RAININ |
|---|---|
| Origin | USA |
| Model | LA6 / LA8 |
| Volume Range Options | EA6-300 (20–300 µL, 6-channel), EA6-1200 (100–1200 µL, 6-channel), EA8-50 (5–50 µL, 8-channel), EA8-300 (20–300 µL, 8-channel), EA8-1200 (100–1200 µL, 8-channel) |
| Power | Rechargeable Lithium-ion Battery (Model 6107-040) |
| Accessories | CR-7 Rotating Stand, HU-M3 Magnetic Hook, HU-S3 Adhesive Hook, HU-A3 Hook Adapter, E3-WPS Wall-Mounted Charging Power Supply, E3-RCS Rapid Charging Station |
Overview
The RAININ EDP3 Adjustable Spacing Electronic Multichannel Pipette is an engineered solution for high-throughput liquid handling in modern life science, pharmaceutical, and clinical laboratories. Built upon the proven EDP3 platform—developed by RAININ, a METTLER TOLEDO company—the instrument integrates precision electromechanical actuation with user-centric ergonomics and adaptive mechanical architecture. Its defining innovation lies in motorized, programmable channel spacing adjustment, enabling seamless transition between microplate formats without manual reconfiguration or accessory swaps. This capability directly addresses workflow bottlenecks in applications such as serial dilution across 24-, 48-, 96-, and 384-well plates, ELISA assay setup, qPCR plate preparation, and cell-based screening workflows. The pipette operates on the principle of positive displacement via integrated brushless DC motors and high-resolution optical encoders, ensuring repeatable piston travel and consistent aspiration/dispense kinetics across all channels. All models comply with ISO 8655-2:2022 for gravimetric performance verification and are calibrated traceable to NIST standards.
Key Features
- Motorized, software-controlled channel spacing adjustment (range: 4.5 mm to 15 mm per channel pair) with tactile feedback and visual confirmation on OLED display
- LTS (Low Retention Tip System) compatibility ensures minimal sample carryover and optimized tip ejection force across all volume ranges
- Five pre-programmed and five user-definable protocols—including reverse pipetting, sequential dispensing, and multi-dispense modes—with adjustable speed, acceleration, and immersion depth
- Integrated rechargeable lithium-ion battery (6107-040) providing ≥1,200 pipetting cycles per full charge; supports hot-swap operation during charging
- IP54-rated housing for resistance to dust and incidental liquid splashes; autoclavable lower assembly (excluding electronics and battery)
- Ergonomic grip geometry and balanced weight distribution reduce operator fatigue during extended multichannel use
Sample Compatibility & Compliance
The EDP3 Adjustable Spacing Pipette accommodates standard conical polypropylene tips (including RAININ LTS and universal-fit tips) and is validated for aqueous, viscous (up to 50% glycerol), and volatile liquids (e.g., ethanol, DMSO). It meets ISO/IEC 17025 requirements for laboratory equipment calibration and supports GLP/GMP documentation workflows through audit-trail-enabled software integration. All volume settings adhere to ISO 8655-6:2022 accuracy specifications (±0.6% at nominal volume for EA8-300, ±1.0% for EA8-50), with repeatability ≤0.2% CV. Device firmware complies with IEC 61326-1:2013 for electromagnetic compatibility and IEC 61010-1:2010 for electrical safety.
Software & Data Management
The pipette interfaces natively with RAININ’s LiteTouch™ PC software (Windows/macOS) for protocol configuration, firmware updates, usage logging, and calibration history export. Audit trails include timestamped records of volume changes, spacing adjustments, calibration events, and error logs—fully compliant with FDA 21 CFR Part 11 requirements when deployed with validated system configurations. Data exports support CSV and PDF formats, and optional integration with LIMS platforms is available via RESTful API. Calibration certificates include uncertainty budgets per ISO/IEC 17025 Annex A.3.
Applications
- High-fidelity transfer between heterogeneous well plate formats (e.g., 24 → 96-well plate reformatting)
- Parallel preparation of dose-response curves in drug discovery assays
- Automated nucleic acid normalization prior to NGS library construction
- Cell seeding and media addition in 3D spheroid and organoid culture workflows
- Quality control testing of raw materials and intermediates under cGMP conditions
- Standard curve generation in immunoassays requiring precise multi-point dilutions
FAQ
What plate formats does the adjustable spacing support?
It supports standard SBS-compliant microplates including 24-, 48-, 96-, and 384-well formats, with continuous spacing adjustment from 4.5 mm to 15 mm.
Is LTS tip compatibility mandatory?
No—while LTS tips deliver optimal performance, the pipette is mechanically compatible with universal-fit tips meeting ISO 8655-8:2022 dimensional tolerances.
Can spacing be adjusted mid-protocol?
Yes—spacing changes can be executed in real time via touchscreen or software command without interrupting ongoing pipetting sequences.
How is calibration verified in regulated environments?
Calibration is performed using gravimetric methods per ISO 8655-2, with documented uncertainty analysis and electronic signature-capable reporting for audit readiness.
Are accessories like the E3-RCS charging station included by default?
No—accessories including the E3-RCS Rapid Charging Station, CR-7 Rotating Stand, and HU-series hooks are optional and ordered separately to match lab infrastructure requirements.
