Sartorius Prospenser Plus Bottle Top Dispenser
| Brand | Sartorius |
|---|---|
| Origin | Germany |
| Model | Prospenser Plus |
| Instrument Type | Manual Bottle Top Dispenser |
| Volume Range | 0.2–60 mL |
| Minimum Increment | 0.05–1.00 mL |
| Accuracy | ±0.60% |
| Error | ±0.20% |
| Sterilization | Full-unit autoclavable at 121 °C, 1 bar |
| Chemical Resistance | Ceramic piston, borosilicate glass sleeve, high-oxidation-resistant polymer components |
| Thread Compatibility | A28, A32, A38, A45, 540 |
| Features | 360° rotatable dispensing head, media recirculation system, Luer port for desiccant tube/filter |
Overview
The Sartorius Prospenser Plus Bottle Top Dispenser is a precision-engineered manual liquid handling instrument designed for repeatable, contamination-controlled dispensing of reagents, solvents, and standards directly from laboratory bottles. Operating on a positive-displacement principle, it utilizes a ceramic piston housed within a borosilicate glass sleeve to eliminate compressibility errors common in air-displacement systems—ensuring volumetric fidelity across diverse chemical classes, including aggressive acids, bases, halogenated solvents, and viscous organic media. Its modular architecture supports seamless integration into GLP- and GMP-compliant workflows, where traceability, reproducibility, and operator safety are non-negotiable. Unlike single-use or low-cost alternatives, the Prospenser Plus is built for long-term operational integrity in high-throughput QC labs, analytical chemistry suites, and regulated pharmaceutical environments.
Key Features
- Ceramic piston and borosilicate glass sleeve deliver exceptional chemical resistance—validated against ISO 8536-4 and compatible with >98% of commonly used laboratory solvents, including concentrated HNO₃, HF (diluted), NaOH (50%), and acetonitrile.
- Full-unit autoclavability at 121 °C and 1 bar pressure enables routine sterilization without disassembly—critical for microbiology, cell culture, and sterile formulation applications.
- 360° rotatable dispensing head allows ergonomic positioning without rotating the reservoir bottle, preserving label visibility and minimizing wrist strain during extended use.
- Integrated media recirculation system returns unused liquid from the dispensing channel back into the source bottle—reducing reagent waste by up to 40% compared to conventional dispensers and maintaining solution homogeneity.
- Luer port on rear housing accepts standard desiccant tubes or hydrophobic filters (e.g., PTFE 0.2 µm), enabling safe handling of moisture-sensitive or volatile compounds such as anhydrous THF or lithium aluminum hydride solutions.
- User-replaceable valve assembly permits field maintenance without service downtime—fully compliant with ISO/IEC 17025 preventive maintenance requirements.
Sample Compatibility & Compliance
The Prospenser Plus accommodates bottles with standard GL-thread interfaces (A28, A32, A38, A45, 540) and supports both narrow- and wide-mouth configurations. Its chemically inert fluid path ensures compatibility with aqueous buffers, organic solvents, corrosive etchants, and high-purity calibration standards. Device construction adheres to EU Directive 2014/30/EU (EMC) and 2014/35/EU (LVD); materials comply with USP Class VI and FDA 21 CFR Part 11–ready documentation protocols when paired with Sartorius LabX software. Calibration certificates (traceable to NIST) are available upon request for audit-ready validation packages.
Software & Data Management
While the Prospenser Plus operates manually, its design integrates seamlessly with Sartorius LabX Liquid Handling software via optional barcode-scanned configuration files. LabX enables electronic recordkeeping of dispense volumes, operator IDs, timestamps, and lot numbers—supporting ALCOA+ data integrity principles. Audit trails meet FDA 21 CFR Part 11 requirements, including electronic signatures, change control logs, and immutable storage. For standalone operation, engraved volume scales and tactile increment stops provide visual and haptic feedback aligned with ISO 8655-3 accuracy tolerances.
Applications
- Preparation of standardized titrants and reference standards in ISO/IEC 17025-accredited testing laboratories.
- Dispensing of hazardous reagents (e.g., osmium tetroxide, bromine water) under fume hood conditions—leveraging closed-system recirculation to minimize vapor exposure.
- QC sampling in pharmaceutical manufacturing per USP and , where consistent volume delivery impacts endotoxin assay sensitivity.
- Media preparation for microbial limit tests (USP ) requiring sterility-preserving transfer without filter clogging.
- Environmental lab workflows involving EPA Method 502.2 and 8081B extractions, where solvent recovery reduces hazardous waste generation.
FAQ
Is the Prospenser Plus suitable for dispensing hydrofluoric acid (HF)?
Yes—when used with appropriate PTFE-coated tubing and operated below 10% concentration; full compatibility data is provided in Sartorius Chemical Resistance Guide v4.2.
Can the device be calibrated in-house?
Yes—gravimetric calibration per ISO 8655-3 is supported using certified balances and distilled water; Sartorius provides downloadable SOP templates and uncertainty calculation worksheets.
Does the media recirculation system require priming?
No—recirculation is passive and pressure-neutral; it activates automatically during each dispense cycle without additional user steps.
What is the maximum viscosity the Prospenser Plus can handle?
Up to 500 mPa·s at 20 °C (e.g., glycerol/water 60:40), provided temperature remains stable and dispensing speed is reduced to ≤1.5 mL/s.
Are replacement parts supplied with batch-specific CoA?
Yes—valve kits, pistons, and glass sleeves ship with individual Certificates of Conformance referencing material lot numbers and dimensional inspection reports.
