Shimadzu AP135W Advanced Analytical Balance

Overview

The Shimadzu AP135W Advanced Analytical Balance is a precision mass measurement instrument engineered for high-reproducibility weighing in regulated laboratory environments. It operates on electromagnetic force compensation (EMFC) principle, where the mass of a sample is determined by the current required to restore equilibrium in a magnetic field—ensuring linearity, long-term stability, and minimal drift. Designed for applications demanding sub-0.1 mg resolution, the AP135W integrates Shimadzu’s proprietary UniBloc AP monolithic sensor architecture: a single-crystal, stress-free load cell structure that eliminates mechanical hysteresis and thermal expansion artifacts common in traditional multi-component sensors. This design directly contributes to improved response time (<2 seconds to stabilization at full capacity), reduced sensitivity to environmental vibration, and enhanced temperature coefficient performance (±0.0005 mg/°C typical). The balance meets fundamental metrological requirements defined in OIML R76-1 and ISO/IEC 17025 for analytical weighing, and is suitable for use in GLP-compliant workflows where traceable, auditable mass data are essential.

Key Features

• UniBloc AP monolithic sensor platform delivering superior mechanical integrity, thermal stability, and long-term calibration retention
• Internal automatic calibration system with motor-driven weights, activated manually or scheduled via time/date triggers
• Real-time dynamic leveling detection with visual on-screen guidance and audible alert for out-of-level conditions
• Integrated draft shield with ergonomic sliding doors and anti-static glass panels (optional STABLO-AP ionizer compatible)
• High-resolution 4.3-inch color TFT touchscreen with intuitive icon-based navigation and multilingual UI (English, Japanese, Chinese, German, French, Spanish)
• RS-232, USB Device, and Ethernet interfaces supporting both ASCII and SICS (Standard Interface Commands for Scales) protocols
• Auto-tare, auto-zero tracking, and programmable filter settings (Fast/Medium/Slow) to optimize stability vs. responsiveness per sample type

Sample Compatibility & Compliance

The AP135W accommodates standard weighing vessels—including aluminum pans, glass beakers, and ceramic crucibles—within its 135 g maximum capacity and 8.5 cm diameter weighing pan. Its compact footprint (220 × 330 × 320 mm) and low profile enable integration into fume hoods, glove boxes, and automated sample handling workstations. The balance complies with ISO 9001 quality management requirements and supports adherence to regulatory frameworks including USP , ASTM E898, and EU Pharmacopoeia 2.1.1. When used with LabSolutions Balance software, it satisfies FDA 21 CFR Part 11 requirements for electronic records and signatures through configurable user roles, audit trail logging, and secure password protection. All internal calibration events and critical operational parameters are timestamped and stored locally with tamper-resistant integrity checks.

Software & Data Management

LabSolutions Balance serves as the central data acquisition and workflow orchestration module for the AP135W. It enables direct bidirectional communication with Shimadzu HPLC, GC, and UV-Vis systems—allowing weight values to be automatically embedded into chromatographic sequence tables or spectroscopic method files. Data export formats include CSV, XML, and PDF (with embedded digital signature). The software maintains a complete audit trail: every weight entry, calibration action, parameter change, or user login is logged with user ID, timestamp, IP address (for networked units), and pre-/post-change values. Raw data files are stored in a structured database with SHA-256 hash verification to ensure forensic integrity during regulatory inspections or method validation.

Applications

• Quantitative preparation of reference standards and working solutions in pharmaceutical QC laboratories
• Weighing of active pharmaceutical ingredients (APIs) prior to dissolution testing per USP
• Gravimetric analysis of ash content, loss-on-drying (LOD), and residual solvents
• Preparation of certified reference materials (CRMs) requiring ≤0.05 mg repeatability
• Calibration of pipettes and volumetric glassware using gravimetric methods per ISO 8655-6
• Micro-weighing of catalysts, nanomaterials, and thin-film substrates in materials science research

FAQ

What is the minimum sample mass recommended for reliable measurement at 0.01 mg readability?
For optimal uncertainty performance per EURAMET cg-18, the minimum weighed mass should be ≥100× the readability—i.e., ≥1 mg under standard laboratory conditions (23 °C ±2 °C, RH <60 %, no drafts).

Does the AP135W support external calibration with traceable weights?
Yes—while internal calibration is standard, the balance accepts external calibration using Class E2 or better certified weights conforming to OIML R111. External calibration mode disables internal weights and logs all actions in the audit trail.

Can LabSolutions Balance be deployed on a centralized server for multi-balance labs?
Yes—the software supports client-server architecture with SQL Server or PostgreSQL backends, enabling concurrent access from up to 64 connected balances and role-based data visibility across departments.

Is the STABLO-AP ionizer included by default?
No—the STABLO-AP electrostatic neutralizer is an optional accessory. When installed, it operates synchronously with the balance’s stabilization cycle and reduces electrostatic-induced deviation to <±0.01 mg for insulating samples such as polymers or dried powders.