Shine CIC-D150 Intelligent Ion Chromatograph

Overview

The Shine CIC-D150 Intelligent Ion Chromatograph is a high-performance, benchtop ion chromatography system engineered for precision anion and cation analysis in environmental, food safety, pharmaceutical, and industrial quality control laboratories. It operates on the fundamental principle of suppressed conductivity detection—where analyte ions are separated on a high-efficiency ion-exchange column and quantified via post-column suppression and conductivity measurement. The system integrates advanced fluidic architecture, real-time leak monitoring, and intelligent thermal management to ensure analytical robustness across diverse sample matrices. Designed for compliance with ISO/IEC 17025 requirements for testing laboratories, the CIC-D150 supports method validation under USP , ASTM D4327, and EPA Methods 300.0, 317.0, and 321.8—enabling trace-level quantification of inorganic anions (e.g., F⁻, Cl⁻, NO₂⁻, Br⁻, NO₃⁻, PO₄³⁻, SO₄²⁻) and low-molecular-weight organic acids (e.g., formate, acetate, oxalate), as well as cations (e.g., Li⁺, Na⁺, NH₄⁺, K⁺, Mg²⁺, Ca²⁺) when equipped with appropriate columns and detectors.

Key Features

• Real-time leak detection system with audible alarm and visual alert on touchscreen and PC interface; automatic pump shutdown after 5 minutes of unacknowledged leakage to prevent electrical damage and baseline drift.
• Auto-ranging conductivity detector delivering linear response from 100 ppb to 100 ppm without manual range selection; digital output in μS/cm with 24-bit ADC resolution.
• Integrated micro-scale gas-liquid separator installed between eluent reservoir and pump head to eliminate dissolved gases, reducing baseline noise and preserving column stability during long-term operation.
• Programmable timed startup (up to 24 hours in advance) enabling full system equilibration—including column conditioning and baseline stabilization—prior to analyst arrival.
• Smart maintenance protocol: automated rinse cycle with deionized water at 0.5 mL/min for 60 minutes, including valve sequencing and flow path purging to minimize carryover and extend column life.
• 10.1-inch capacitive touchscreen with intuitive UI for local instrument control, status monitoring, and diagnostic access; supports direct instrument power cycling, maintenance initiation, and parameter adjustment.
• Mobile remote monitoring and control via secure iOS/Android application with TLS 1.2 encrypted communication, supporting real-time pressure, temperature, conductivity, and flow rate visualization.

Sample Compatibility & Compliance

The CIC-D150 accommodates aqueous samples with total dissolved solids (TDS) ≤ 100 mg/L and particulate content < 0.45 µm (pre-filtered). It is compatible with standard IC-compatible vials (e.g., 2-mL polypropylene), autosampler trays (up to 120 positions), and third-party sample preparation modules (e.g., inline filtration, dilution, and derivatization units). Column compatibility includes Shine SH series PEEK-based anion-exchange columns (e.g., SH-AC-3, SH-AC-7) and cation-exchange columns (e.g., SH-CC-2), all rated for pH 0–14 and fully compatible with organic modifiers (e.g., methanol, acetonitrile). System architecture conforms to IEC 61000-6-3 (EMC) and IEC 61010-1 (safety); software supports audit trail, electronic signatures, and 21 CFR Part 11-compliant data integrity controls when deployed with optional GLP/GMP module.

Software & Data Management

The proprietary ChromSolution™ software provides full instrument control, sequence management, peak integration, and report generation in accordance with ISO 14155 and CLSI EP22-A guidelines. Raw data are stored in vendor-neutral .cdf format (compatible with OpenChrom and Chromeleon), with embedded metadata including instrument configuration, calibration history, and user-defined QC flags. Data archiving supports network-attached storage (NAS) or LIMS integration via HL7 or ASTM E1384 interfaces. All method files include version control, change logs, and timestamped operator IDs. Optional e-signature package enables role-based access, workflow approval routing, and FDA audit-ready documentation.

Applications

The CIC-D150 is routinely deployed in accredited environmental labs for EPA Method 300.0 (drinking water anions), 317.0 (perchlorate), and 321.8 (disinfection byproducts); in food testing labs for nitrate/nitrite in meat products (AOAC 2010.02), iodide in dairy (ISO 20649), and sulfite in wines (OIV-OENO 505-2021); and in battery electrolyte R&D for Li⁺, PF₆⁻, and TFSI⁻ quantification. When coupled with ICP-MS via a dedicated IC-ICP-MS interface kit, it enables speciation analysis of As(III)/As(V), Cr(III)/Cr(VI), and Se(IV)/Se(VI) per ISO 17294-2 and EN 16466. Optional amperometric detection supports trace cyanide (ASTM D7511), iodide, and carbohydrate profiling in biopharmaceutical excipients.

FAQ

Does the CIC-D150 support gradient elution without a dedicated gradient pump?
Yes—the integrated electrolytic eluent generator enables on-demand production of carbonate, hydroxide, or methanesulfonic acid gradients using only ultrapure water as input, eliminating manual eluent preparation and gradient pump hardware.
Is the system compatible with third-party ICP-MS instruments?
Yes—it features standardized PEEK capillary connections and configurable flow-splitting modules to interface with Thermo Fisher iCAP, Agilent 8900, PerkinElmer NexION, and domestic ICP-MS platforms.
What column chemistries are validated for use with the CIC-D150?
Shine SH-series columns (anion: AS18, AS23, AS26; cation: CS12A, CS16) are factory-qualified; all support pH 0–14, 35 MPa pressure rating, and >5,000 injections lifetime under recommended operating conditions.
How is data integrity ensured during regulatory audits?
With optional 21 CFR Part 11 module enabled, the system enforces electronic signature workflows, immutable audit trails, and role-based permissions—fully aligned with ALCOA+ principles for GxP environments.
Can the mobile app be used for method transfer between instruments?
Yes—method files (.csm) exported from ChromSolution™ can be imported directly into other CIC-D150 units via QR code scan or cloud sync, ensuring consistent retention time and peak area reproducibility across multi-site deployments.