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SPN-500A Nitrogen Generator by Sinopharm Chemical Reagent Co., Ltd.

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Origin Beijing, China
Manufacturer Type Authorized Distributor
Origin Category Domestic (China)
Model SPN-500A
Pricing Available Upon Request
Nitrogen Purity O₂ < 3 ppm, Dew Point ≤ −56 °C
Flow Rate 0–500 mL/min
Output Pressure 0–0.4 MPa
Pressure Stability < 0.003 MPa (dependent on inlet air supply stability)
Power Supply 220 V ±10%, 50 Hz
Power Consumption 150 W
Operating Environment 1–40 °C, RH < 85%
Dimensions (W×D×H) 360 × 200 × 260 mm
Net Weight ~9 kg

Overview

The SPN-500A Nitrogen Generator is a compact, membrane-based gas separation system engineered for continuous, on-demand nitrogen supply in analytical laboratories. It utilizes selective permeation through hollow-fiber polymeric membranes to separate nitrogen from compressed ambient air—removing oxygen, water vapor, and trace hydrocarbons via differential diffusion rates. This physical separation method eliminates the need for consumables such as chemical scrubbers or cryogenic tanks, delivering high-purity nitrogen with consistent flow and pressure control. Designed for integration with gas chromatography (GC), liquid chromatography-mass spectrometry (LC-MS), elemental analyzers, and other instrumentation requiring inert purge or carrier gas, the SPN-500A supports uninterrupted operation under standard lab conditions without external gas cylinders.

Key Features

  • Real-time digital display of output pressure and nitrogen flow rate, enabling immediate operational verification and process monitoring.
  • Auto-regulating pressure and flow control circuitry ensures stable delivery across variable demand—flow automatically adjusts from 0 to 500 mL/min without manual intervention or external regulators.
  • Stainless steel pre-filtration assembly combined with low-sulfur silicone O-rings minimizes trace metal and sulfur compound contamination, critical for maintaining GC baseline stability and detector longevity.
  • Integrated safety architecture includes automatic anti-backflow protection and alkaline solution containment safeguards—preventing reverse migration of desiccant or filter media into the gas stream.
  • Energy-efficient design consumes only 150 W during continuous operation, supporting sustainable lab infrastructure goals without compromising performance.
  • Compact footprint (360 × 200 × 260 mm) and lightweight construction (~9 kg) facilitate benchtop deployment in space-constrained environments including QC labs, research facilities, and mobile analytical units.

Sample Compatibility & Compliance

The SPN-500A is compatible with all standard laboratory-grade compressed air sources meeting ISO 8573-1 Class 3:3:3 specifications (oil-free, particulate ≤ 5 µm, dew point ≤ −20 °C). Its nitrogen output meets ASTM D6625 requirements for high-purity carrier gas in chromatographic applications and complies with general instrumental gas purity guidelines outlined in USP , EP 2.2.43, and ICH Q5C. While not certified to ISO/IEC 17025 or FDA 21 CFR Part 11 out-of-the-box, its stable output parameters support GLP/GMP-aligned documentation when integrated into validated workflows using external audit-trail-capable data loggers.

Software & Data Management

The SPN-500A operates as a standalone hardware unit with no embedded firmware or proprietary software interface. All operational parameters—including pressure, flow, and runtime—are displayed locally via LED indicators. For laboratories requiring electronic recordkeeping, analog voltage outputs (0–5 V or 4–20 mA) can be interfaced with third-party SCADA systems, LIMS platforms, or programmable logic controllers (PLCs) for automated logging, alarm triggering, and preventive maintenance scheduling. No driver installation or vendor-specific configuration tools are required.

Applications

  • Carrier gas supply for capillary GC and GC-MS systems requiring ultra-low oxygen and moisture content.
  • Purge gas for headspace samplers, thermal desorption units, and autosampler needle wash stations.
  • Inert blanket gas for sample preparation workflows involving oxidation-sensitive compounds (e.g., pharmaceutical stability testing, polymer analysis).
  • Zero-air generation support when paired with catalytic converters for environmental air monitoring calibrations.
  • Lab-scale nitrogen supply for glovebox purging, solvent evaporation systems, and electrochemical cell testing.

FAQ

What compressed air quality is required for optimal SPN-500A performance?
A clean, oil-free air supply with dew point ≤ −20 °C and particulate filtration down to 0.01 µm is recommended. Use of an inline coalescing filter and refrigerated dryer upstream is strongly advised to extend membrane life and maintain specified purity.
Can the SPN-500A be used with mass spectrometers requiring ultra-high-purity nitrogen?
While suitable for most LC-MS nitrogen curtain gas and nebulizer gas applications, it does not meet the <1 ppm O₂ and <−70 °C dew point specifications required for high-resolution MS source gases; supplemental purification modules may be necessary.
Is routine maintenance required beyond filter replacement?
Yes—pre-filter elements should be replaced every 6–12 months depending on air quality; membrane lifetime is typically 3–5 years under compliant operating conditions. No user-serviceable internal components require calibration.
Does the unit support remote monitoring or alarm outputs?
No native Ethernet or USB interface is provided, but optional analog signal outputs (available upon request) enable connection to building management systems or centralized lab monitoring networks.
How does ambient temperature affect nitrogen dew point stability?
Operating within the specified 1–40 °C range ensures consistent membrane permeability and adsorption kinetics; deviations outside this range may reduce dew point performance and increase O₂ breakthrough risk.

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