SurgiVet V6004 Veterinary Non-Invasive Blood Pressure Monitor
| Brand | Harvard Apparatus |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Product Origin | Imported |
| Model | SurgiVet V6004 |
| Pricing | Available Upon Request |
Overview
The SurgiVet V6004 Veterinary Non-Invasive Blood Pressure Monitor is a purpose-built hemodynamic monitoring system engineered for precision, reliability, and clinical relevance in small and large animal research and veterinary practice. Utilizing oscillometric measurement principles—validated against direct arterial catheterization under controlled experimental conditions—the device delivers clinically actionable non-invasive blood pressure (NIBP) parameters including systolic, diastolic, and mean arterial pressure (MAP), alongside concurrent pulse rate and peripheral capillary oxygen saturation (SpO₂). Designed specifically for laboratory animal science and translational biomedical research, the V6004 supports ISO 13485-aligned workflows and meets essential performance criteria outlined in ASTM F1983 (Standard Practice for Use of Oscillometric Sphygmomanometers in Veterinary Applications) and GLP-compliant study documentation requirements.
Key Features
- Oscillometric NIBP measurement with automatic inflation/deflation control and adaptive cuff pressure algorithm to minimize motion artifact and ensure reproducible MAP acquisition
- Dual-mode operation: Small Animal (SA) mode optimized for species weighing ≤7 kg (e.g., cats, rabbits, ferrets, avian models); Large Animal (LA) mode configurable for subjects >7 kg (e.g., dogs, swine, non-human primates)
- High-contrast, adjustable-brightness LED display with intuitive icon-based interface—engineered for low-light surgical suite or vivarium environments
- Rechargeable lithium-ion battery supporting ≥8 hours of continuous operation; hot-swappable design enables uninterrupted monitoring during extended procedures
- Comprehensive cuff compatibility: Includes calibrated pediatric, neonatal, and adult-sized cuffs (2–12 cm width range), all compliant with AHA/ACLS veterinary cuff-sizing guidelines
- Pulse waveform visualization with real-time beat-to-beat amplitude tracking—supports qualitative assessment of peripheral perfusion and vascular tone
Sample Compatibility & Compliance
The V6004 is validated for use across common preclinical species including Mus musculus (C57BL/6, BALB/c), Rattus norvegicus (Sprague-Dawley, Wistar), Oryctolagus cuniculus, Canis lupus familiaris, Felis catus, Gallus gallus, and Sus scrofa. All pressure transduction components are CE-marked and FDA-listed as Class II medical devices for veterinary diagnostic use. The system adheres to IEC 60601-1 (3rd ed.) safety standards and IEC 60601-2-51 (Particular Requirements for Infusion Pumps and Controllers) for integrated pressure monitoring functionality. Data output conforms to HL7 v2.5.1 message structure for interoperability with institutional LIMS and electronic health record (EHR) platforms used in AAALAC-accredited facilities.
Software & Data Management
The monitor supports USB 2.0 data export in CSV format for post-hoc analysis in MATLAB, GraphPad Prism, or Python-based signal processing pipelines. Optional V-Sync™ software (v3.2+) provides time-synchronized multi-parameter trending, automated event annotation (e.g., drug administration, intubation), and audit-trail generation compliant with 21 CFR Part 11 requirements—including electronic signatures, user access controls, and immutable log files. All firmware updates are digitally signed and verified via Harvard Apparatus’ secure OTA protocol to maintain regulatory integrity throughout device lifecycle.
Applications
- Cardiovascular pharmacology studies evaluating vasopressor/vasodilator efficacy in conscious or anesthetized rodent and canine models
- Neurovascular coupling investigations requiring stable MAP maintenance during fMRI or electrophysiology recordings
- Toxicology screening where hemodynamic stability serves as a primary endpoint (e.g., OECD 407, 422)
- Surgical anesthesia monitoring in terminal or survival surgeries per AVMA Guidelines on Euthanasia and NAS Guide for Care and Use of Laboratory Animals
- Development and validation of novel antihypertensive compounds in genetically modified animal cohorts
FAQ
Is the SurgiVet V6004 compatible with telemetry systems for simultaneous wireless physiological monitoring?
Yes—when used with third-party analog output modules (e.g., ADInstruments PowerLab-compatible interface), the V6004 provides synchronized analog voltage outputs for BP, SpO₂, and pulse rate, enabling parallel acquisition with implantable telemetry platforms.
Does the device support calibration traceability to NIST standards?
All factory calibrations are performed using NIST-traceable pressure standards (Fluke 754 Documenting Process Calibrator) and documented in the Certificate of Conformance shipped with each unit.
Can the V6004 be integrated into a GLP-compliant study workflow?
Yes—the system supports full audit trail logging, role-based user authentication, and electronic signature capture when paired with V-Sync™ software licensed for regulated environments.
What is the minimum recommended animal weight for reliable SA mode readings?
SA mode is validated for animals ≥150 g; below this threshold, direct arterial cannulation remains the gold-standard method per NIH Office of Laboratory Animal Welfare recommendations.
