Thermo Fisher Aquanex Ultra-Pure Water System
| Brand | Thermo Fisher |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Authorized Distributor |
| Product Origin | Domestic (China) |
| Model | Aquanex Ultra-Pure Water System |
| Pricing | Upon Request |
| Water Purity Grade | ASTM Type I (Ultra-Pure Water) |
Overview
The Thermo Fisher Aquanex Ultra-Pure Water System is an integrated, modular laboratory water purification platform engineered to deliver consistent ASTM Type I ultrapure water (resistivity ≥18.2 MΩ·cm at 25 °C, total organic carbon <5 ppb, bacteria <0.1 CFU/mL, and particulates <1 particle/mL >0.2 µm) for critical analytical, life science, and quality control applications. Utilizing a multi-stage purification architecture—including pretreatment (activated carbon + dual-stage reverse osmosis), electrodeionization (EDI), and final polishing via ultra-low leaching mixed-bed ion exchange and 0.2 µm absolute-rated final filtration—the system ensures robust removal of ions, organics, colloids, microorganisms, and particles. Its design adheres to ISO 3696:1987 and ASTM D1193-20 for laboratory reagent water specifications, supporting compliance with GLP, GMP, and ISO/IEC 17025 quality management frameworks.
Key Features
- Intelligent Touchscreen Dispensing Arm: Integrated Type I ultrapure water dispensing arm with capacitive touchscreen interface enabling precise volume-based or continuous manual dispensing—fully programmable with user-defined flow rates, volume limits, and dispensing modes (e.g., rinse, fill, purge).
- Modular Front Access Design: Magnetically secured, tool-free front panel allows rapid visual inspection and hot-swappable replacement of consumables—including RO membranes, EDI modules, and final polishing cartridges—minimizing system downtime and simplifying preventive maintenance.
- Auto-Recognition Cartridge Technology: Each certified Thermo Fisher Aquanex purification cartridge contains embedded RFID or NFC tags that automatically register installation date, batch number, and service life; the system logs usage hours and triggers dynamic replacement alerts based on actual throughput and real-time water quality metrics.
- Embedded Intelligence Suite: 7-inch high-resolution color touchscreen running embedded Linux OS provides centralized configuration of dispensing parameters, alarm thresholds, user access levels (admin/operator/guest), and audit-trail-enabled event logging compliant with FDA 21 CFR Part 11 requirements (including electronic signatures and immutable log history).
- Eco-Optimized Operation Modes: Selectable operational profiles—including Eco Mode (reduced standby power and optimized regeneration cycles), High-Throughput Mode (maximized flow rate up to 2.0 L/min at point-of-use), and Low-Flow Precision Mode (for sensitive applications requiring sub-mL accuracy)—enable laboratory managers to balance water purity, energy consumption, and consumable longevity.
Sample Compatibility & Compliance
The Aquanex system is validated for continuous production of ultrapure water compatible with HPLC, LC-MS, ICP-MS, cell culture media preparation, molecular biology workflows (e.g., PCR, sequencing), and trace metal analysis. All wetted materials comply with USP Class VI biocompatibility standards and are extractables-tested per USP <661.1>. The system meets ISO 14644-1 Class 5 cleanroom-compatible construction requirements for housing in controlled environments. Documentation packages include Factory Acceptance Test (FAT) reports, IQ/OQ protocols, and full traceability of calibration certificates for integrated conductivity, TOC, and temperature sensors—all aligned with ISO/IEC 17025 calibration hierarchy requirements.
Software & Data Management
Data integrity is ensured through built-in audit trail functionality recording all user actions, parameter changes, alarm events, and cartridge swaps with timestamps, operator IDs, and reason-for-change fields. Exportable logs (CSV/Excel) support integration into LIMS or ELN platforms via standard USB or Ethernet interfaces. Remote monitoring capability (optional) enables SNMP-based network alerts and secure HTTPS web interface access for multi-site fleet management. Software firmware updates are digitally signed and verified prior to installation to maintain regulatory compliance continuity.
Applications
- HPLC and UHPLC mobile phase preparation and instrument rinsing
- LC-MS and GC-MS solvent blanks and calibration standards
- Cell culture media formulation and sterile filtration support
- DNA/RNA extraction, qPCR, NGS library preparation
- Atomic spectroscopy (ICP-OES, ICP-MS) diluent and standard preparation
- Electrophysiology and patch-clamp solutions requiring low endotoxin and ion-free water
- Pharmaceutical QC testing per USP <1231> Water for Injection (WFI) support protocols
FAQ
What water quality standards does the Aquanex system meet?
It consistently delivers ASTM Type I ultrapure water per ASTM D1193-20 and ISO 3696:1987, with additional validation support for USP Purified Water and WFI auxiliary use cases.
Can the system be integrated into a central laboratory water network?
Yes—Aquanex supports looped distribution configurations with optional recirculation pumps, UV oxidation units, and real-time loop monitoring sensors for multi-point delivery.
Is remote diagnostics and service support available?
Thermo Fisher offers optional Thermo Connect™ remote connectivity for predictive maintenance alerts, firmware updates, and secure technician-assisted troubleshooting.
How is data integrity maintained for regulated environments?
All system logs are time-stamped, user-authenticated, non-erasable, and exportable—fully compliant with FDA 21 CFR Part 11, EU Annex 11, and ISO/IEC 17025 documentation requirements.
What is the expected service life of the final polishing cartridge?
Typical lifespan ranges from 6–12 months depending on feed water quality and daily usage volume; the system calculates remaining capacity dynamically using real-time resistivity decay modeling.
