Thermo Fisher TriPlus AS Autosampler (Refurbished)

Overview

The Thermo Fisher TriPlus AS Autosampler is a high-precision, robotically driven liquid-handling platform engineered for seamless integration with gas chromatography (GC) and liquid chromatography (LC) systems. Based on a robust Cartesian X-Y-Z motion architecture, the TriPlus AS delivers reproducible, low-carryover sample introduction through programmable syringe-based injection. Its design adheres to core principles of analytical automation: positional accuracy (±0.1 mm), volumetric precision (<0.5% RSD for repeated injections under standardized conditions), and method-driven operational repeatability. This refurbished unit has undergone full functional validation at SpectraLab Scientific’s ISO/IEC 17025-accredited calibration facility, including syringe leakage testing, needle alignment verification, vial tray positioning accuracy assessment, and multi-solvent wash cycle performance evaluation. All mechanical axes, stepper motor drivers, and fluidic path components—including the high-pressure sealing system and PTFE-coated plunger—have been inspected, cleaned, and reconditioned per Thermo Fisher service bulletins.

Key Features

• Three-axis robotic arm with independent X, Y, and Z motion control enabling flexible deck layout and unattended operation across heterogeneous vial formats
• Auto-detecting syringe recognition for 5 µL, 10 µL, 100 µL, and 250 µL models—ensuring correct volume scaling and pressure compensation
• Precision injection range from 0.1 µL to 250 µL in 0.1 µL increments, configurable per method with real-time feedback on plunger position and dwell time
• Adjustable needle depth: 50 mm for split injection, 80 mm for splitless or on-column injection—mechanically locked and verified during qualification
• Dual-wash station architecture supporting either four 10 mL solvent reservoirs or two 100 mL bottles, with programmable pre- and post-injection rinse sequences
• Integrated waste management: internal 10 mL collection vial or direct external drain connection compliant with lab ventilation standards
• Multi-solvent combinatorial rinse capability (up to 4 solvents) with independent valve sequencing to minimize cross-contamination in trace-level analysis

Sample Compatibility & Compliance

The TriPlus AS accommodates standard screw-thread and crimp-top vials in volumes of 1 mL, 2 mL, 2.5 mL, 10 mL, and 20 mL. Maximum capacity is 300 positions for 1–2.5 mL vials and 108 positions for 10–20 mL formats. All sample trays are manufactured from anodized aluminum with laser-etched position indexing for long-term dimensional stability. The system complies with ASTM D4057 (standard practice for manual sampling of petroleum and petroleum products) and supports GLP/GMP workflows via optional audit-trail-enabled software modules. While the hardware itself does not require FDA 21 CFR Part 11 certification, its operation within validated chromatographic methods aligns with data integrity expectations outlined in Annex 11 and USP .

Software & Data Management

The TriPlus AS operates under Thermo Fisher’s Chromeleon CDS (Chromatography Data System) v7.3 or later. Method parameters—including injection volume, needle penetration depth, wash solvent sequence, incubation time, and syringe speed—are stored as encrypted binary objects with version-controlled revision history. Raw instrument logs (motion timestamps, syringe pressure events, valve actuation cycles) are retained for ≥90 days and exportable in CSV format for third-party statistical process control (SPC) analysis. No cloud connectivity or remote telemetry is enabled by default; all data remains on-premise unless explicitly configured by the end user.

Applications

This autosampler is routinely deployed in environmental testing labs for EPA Method 8260/8270 volatile and semi-volatile organic compound analysis, pharmaceutical QC for residual solvent quantification (ICH Q2(R2)), and food safety laboratories performing pesticide residue screening per AOAC 2007.01. Its low dead-volume fluidic path and thermal-stable needle housing support quantitative analysis of thermally labile compounds such as aldehydes, lactones, and nitrosamines. The modular deck design also permits co-location with solid-phase microextraction (SPME) or headspace samplers when configured with auxiliary mounting brackets.

FAQ

Is this unit compatible with Agilent or Shimadzu GC systems?
Yes—via analog I/O triggering and RS-232/USB command emulation; full compatibility requires firmware revision ≥2.14 and optional interface module (PN: 08-022171).
Does the 6-month warranty cover syringe replacement?
Yes—original equipment manufacturer (OEM) syringes and needle assemblies are included under parts-and-labor coverage.
Can the TriPlus AS be upgraded to support SPME fiber handling?
Yes—retrofit requires installation of the TriPlus SPME accessory kit (PN: 08-022182) and corresponding deck plate modification.
What documentation accompanies the instrument?
A full refurbishment report, calibration certificate traceable to NIST standards, and electronic copies of the Thermo Fisher service manual and safety compliance dossier are provided.
Is remote diagnostics supported?
No—this unit ships without embedded telemetry hardware; remote access requires customer-provided secure VPN and local IT approval per site security policy.