Titan DB2-100 Dry Block Thermostat with Heating and Cooling Function (Module Not Included)

Overview

The Titan DB2-100 is a compact, Peltier-based dry block thermostat engineered for precise temperature control across both heating and cooling domains without requiring external chillers or cryogenic fluids. Unlike traditional water baths or air-circulating ovens, this device employs solid-state thermoelectric (TEC) modules to achieve bidirectional thermal regulation—enabling stable setpoint maintenance from 0 °C to 100 °C with typical stability of ±0.2 °C at 37 °C and ±0.3 °C across the full range. Its dry-block architecture eliminates contamination risks associated with liquid media and supports rapid thermal equilibration—critical for applications demanding repeatable incubation, enzyme inactivation, or sample pre-conditioning prior to downstream analysis (e.g., PCR setup, ELISA plate warming, or serum thawing). Designed for integration into QC labs, clinical diagnostics workflows, and academic research environments, the DB2-100 operates independently of ambient humidity or ventilation constraints.

Key Features

• Peltier-driven dual-mode operation: simultaneous heating and active cooling without compressor or refrigerant
• Dry-block aluminum heating block with high thermal conductivity and uniformity (±0.4 °C across block surface at 50 °C)
• Intuitive 4.3-inch capacitive touchscreen interface with real-time temperature graphing and programmable ramp/soak profiles
• Independent safety circuitry including over-temperature cutoff (110 °C), short-circuit protection, and open-sensor detection
• RS-232 and USB-B ports for instrument control and data logging via PC; compatible with optional TitanLab Control Suite (v3.2+)
• Compact footprint (240 × 170 × 160 mm) and low power consumption (<120 W nominal at 37 °C)

Sample Compatibility & Compliance

The DB2-100 accepts standard interchangeable aluminum blocks (sold separately), supporting common labware formats including 0.2 mL, 0.5 mL, 1.5 mL, and 2.0 mL microcentrifuge tubes, 96-well PCR plates, and 12 × 75 mm culture tubes. Its design conforms to IEC 61010-1:2010 for electrical safety in laboratory equipment and meets EMC requirements per EN 61326-1:2013. While not certified for medical device use under ISO 13485, it is routinely deployed in GLP-compliant environments where traceable calibration and audit-ready operation are required. Optional NIST-traceable calibration certificate (per ISO/IEC 17025) is available upon request.

Software & Data Management

TitanLab Control Suite (Windows-compatible) enables remote monitoring, multi-step protocol execution, and time-stamped data export in CSV format. The software supports user-level access control (admin/operator modes), electronic signature capture, and audit trail generation compliant with FDA 21 CFR Part 11 requirements when configured with Windows domain authentication and encrypted local storage. All temperature logs include sensor ID, setpoint, actual reading, deviation, and timestamp—facilitating retrospective review during internal audits or regulatory inspections. Firmware updates are delivered via secure HTTPS channel and validated through SHA-256 checksum verification.

Applications

• Enzyme reaction incubation and heat-inactivation steps in molecular biology workflows
• Controlled thawing of frozen reagents, standards, or clinical specimens to minimize thermal shock
• Pre-warming of assay plates and buffers prior to immunoassay or cell-based assays
• Stabilization of temperature-sensitive enzymes (e.g., restriction endonucleases, ligases) during benchtop handling
• Calibration reference point generation for secondary temperature sensors in validation protocols
• Supporting ASTM E2875-22 (Standard Guide for Temperature Calibration of Dry-Block Calibrators) in metrology labs

FAQ

Does the DB2-100 require external cooling water or refrigerant gas?

No—its Peltier-based cooling system operates without compressors, condensers, or consumable refrigerants.
Can I use my existing aluminum blocks from other dry bath systems?

Only Titan-certified DB-series blocks are mechanically and thermally validated for use with the DB2-100; third-party blocks may compromise accuracy or safety.
Is the device suitable for GMP-regulated production environments?

Yes—when paired with Titan’s optional IQ/OQ documentation package and calibrated annually per ISO/IEC 17025, it satisfies baseline qualification requirements for ancillary lab equipment in pharmaceutical manufacturing.
What is the maximum ramp rate achievable?

From 25 °C to 70 °C: ≤12 minutes; from 25 °C to 4 °C: ≤18 minutes (load-dependent, measured with 1.5 mL tube filled with 1 mL water).
How is temperature uniformity verified across the block?

Titan performs 9-point mapping using calibrated Pt100 probes traceable to NPL standards; full validation report available upon request.