Titan MRC-20K Max Benchtop High-Speed Refrigerated Centrifuge
| Brand | Titan |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Instrument Type | Benchtop Centrifuge |
| Speed Range | High-Speed (10,000–30,000 rpm) |
| Function | Refrigerated Centrifugation |
| Configuration | Fixed-Angle Rotor System |
| Maximum Capacity | 4 × 750 mL |
| Maximum Speed | 20,000 rpm |
| Maximum RCF | 28,260 × g |
| Dimensions (W × D × H) | 750 × 663 × 407 mm |
Overview
The Titan MRC-20K Max is a high-performance benchtop refrigerated centrifuge engineered for precision separation of biological, clinical, and industrial samples under controlled thermal conditions. Utilizing brushless frequency-controlled motor technology and a robust aluminum alloy rotor chamber, it delivers stable rotational dynamics across its full operational range — from 200 rpm to 20,000 rpm — with RCF values reaching up to 28,260 × g. Its active refrigeration system maintains sample temperature between –20 °C and +40 °C, independent of ambient conditions, ensuring integrity of thermolabile macromolecules such as nucleic acids, proteins, organelles, and viral particles during high-speed sedimentation. Designed for routine use in core facilities, QC laboratories, and academic research environments, the MRC-20K Max complies with IEC 61010-1 safety standards for laboratory equipment and incorporates dual-stage refrigerant circulation for rapid cooldown and uniform thermal distribution.
Key Features
- Intelligent microprocessor control with real-time display of speed, RCF, time, temperature, and acceleration/deceleration profiles
- Four-position fixed-angle rotor configuration supporting up to 4 × 750 mL conical tubes (e.g., 500 mL polypropylene bottles), enabling high-throughput processing without compromising balance stability
- Automatic rotor identification via embedded RFID tags — prevents mismatched rotor operation and enforces speed/temperature limits per rotor specification
- Three-stage deceleration programming (fast, slow, no-brake) to preserve pellet integrity in sensitive applications such as exosome isolation or mitochondrial fractionation
- Double-layer insulated stainless-steel chamber with vacuum-sealed door gasket, minimizing condensation and enhancing thermal efficiency
- Integrated imbalance detection and automatic shutdown at ≥5 g deviation, compliant with ISO 13485 risk management requirements for medical device manufacturing support labs
Sample Compatibility & Compliance
The MRC-20K Max accommodates standard centrifuge tube formats including 15 mL, 50 mL, and 500 mL conical tubes, as well as custom-designed 750 mL containers compatible with GMP-grade bioprocessing workflows. Rotor geometry has been validated for use with both polymer and metal tubes under ASTM F2119-22 mechanical stress protocols. All temperature-controlled operations meet GLP documentation requirements through built-in audit trail functionality (user login, parameter changes, run logs). The unit is CE-marked and conforms to EN 61326-1 (EMC) and EN 61000-6-3 (emission) standards. Optional validation packages support IQ/OQ documentation aligned with FDA 21 CFR Part 11 for regulated pharmaceutical and diagnostic labs.
Software & Data Management
Equipped with TitanCentriLink™ PC software (Windows/macOS compatible), the MRC-20K Max supports method export/import, remote monitoring via Ethernet/Wi-Fi, and encrypted CSV data logging. Each run record includes timestamped metadata: rotor ID, setpoint vs. actual temperature curve, speed ramp profile, total run duration, and final RCF achieved. Audit trails are digitally signed and tamper-evident, satisfying traceability mandates under ISO/IEC 17025 accreditation. For integration into LIMS environments, the instrument provides HL7-compliant output and supports OPC UA communication protocol.
Applications
- Cell fractionation: isolation of nuclei, mitochondria, lysosomes, and plasma membranes from mammalian, plant, and microbial cell lysates
- Viral vector purification: concentration and clarification of AAV, lentivirus, and adenovirus preparations prior to chromatographic polishing
- Biotherapeutic downstream processing: harvesting of CHO or HEK293 cell cultures at pilot scale (≤750 mL batch volume)
- Clinical diagnostics: rapid serum/plasma separation from whole blood in high-volume hospital labs
- Environmental microbiology: concentration of waterborne pathogens (e.g., Cryptosporidium oocysts) using high-capacity bottle rotors
- Nanoparticle characterization: pre-clearing of liposome or polymeric nanoparticle suspensions before DLS or TEM analysis
FAQ
What is the minimum operating temperature and how quickly does the chamber reach –20 °C from ambient?
The refrigeration system achieves –20 °C within 18 minutes when starting from 25 °C, verified per ISO 13485 environmental test procedure.
Can the MRC-20K Max accommodate swinging-bucket rotors?
No — it is configured exclusively for fixed-angle rotors optimized for high-RCF pelleting; swinging-bucket compatibility is not supported due to structural and thermal design constraints.
Is rotor calibration required annually, and does Titan provide certified calibration services?
Yes — annual rotor calibration is recommended and available through Titan’s authorized service centers, with NIST-traceable certificates issued per ISO/IEC 17025.
Does the centrifuge support password-protected user accounts with role-based access control?
Yes — up to 16 user profiles with configurable permissions (operator, supervisor, administrator) are supported via the onboard interface and TitanCentriLink™ software.
Are spare rotors and adapters supplied with CE or FDA registration documentation?
All rotors carry CE marking and are accompanied by Declaration of Conformity; FDA registration documentation is provided upon request for U.S.-based end-users engaged in regulated manufacturing or testing.
