WAYEAL IC6600 Series Multi-Function Ion Chromatograph
| Brand | WAYEAL |
|---|---|
| Origin | Anhui, China |
| Manufacturer Type | Manufacturer |
| Product Category | Domestic |
| Model | IC6600 Series |
| Instrument Type | Laboratory |
| Application Scope | General-Purpose |
| Pump Maximum Pressure | 35 MPa |
| Flow Rate Range | 0.001–10.000 mL/min |
| Eluent Flow Rate Range | 0.001–10.000 mL/min |
| Max Operating Pressure | 35 MPa (main unit) / 21 MPa (eluent generator) |
| Operating Temperature Range | 4–65 °C |
| Temperature Reproducibility | ±0.005 °C |
| Eluent Concentration Range | 0–100 mmol/L (KOH) |
Overview
The WAYEAL IC6600 Series Multi-Function Ion Chromatograph is a modular, high-performance analytical platform engineered for precision anion and cation separation in regulated and research laboratory environments. Based on suppressed conductivity detection principles—complemented by amperometric and UV detection options—the system delivers quantitative analysis of inorganic ions (e.g., F⁻, Cl⁻, NO₃⁻, SO₄²⁻, Na⁺, K⁺, NH₄⁺), oxyanions (e.g., CrO₄²⁻, IO₃⁻), cyanide, iodide, low-molecular-weight organic acids, carbohydrates, and transition metals via post-column derivatization. Its architecture integrates electrochemical eluent generation, multi-zone thermal control, and flexible detector interchangeability to support method development, routine QC, and advanced applications including speciation analysis and hyphenated techniques (e.g., IC-MS).
Key Features
- Modular Fluidic Architecture: Independent plug-and-play modules—including quaternary gradient or isocratic pumps, electrolytic eluent generators (OH⁻, CO₃²⁻, MSA), conductivity/amperometric/UV detectors, and post-column reactors—enable application-specific configuration and future scalability.
- Electrolytic Eluent Generation: “Water-only” operation via membrane-based electrodialysis eliminates manual eluent preparation; supports KOH concentration tuning from 0–100 mmol/L with <±0.005 °C thermal stability across five independently controlled temperature zones (pump, column oven, detector cell, eluent generator, and autosampler).
- High-Resolution Flow Control: Brushless DC motor-driven pump delivers stable flow from 0.001–10.000 mL/min at up to 35 MPa (main unit) or 21 MPa (eluent generator), ensuring reproducible gradient formation and long-term pressure integrity.
- Detector Flexibility: Interchangeable detection modes: suppressed conductivity (with optional dual-channel capability), pulsed amperometric detection (PAD), and variable-wavelength UV detection (190–400 nm); PAD supports DC, pulsed, and integrated pulse modes for carbohydrate and amino acid analysis.
- Advanced Autosampling: Programmable autosampler enables simultaneous anion/cation injection, timed sequential injection, on-line matrix elimination, and trace-enrichment protocols—reducing carryover and improving detection limits for environmental and food safety testing.
Sample Compatibility & Compliance
The IC6600 accommodates aqueous samples across diverse matrices—including drinking water, wastewater, pharmaceutical excipients, battery electrolytes, and biological fluids—following standard pretreatment (filtration, dilution, solid-phase extraction). Its design aligns with ISO 10304-1:2012 (determination of dissolved anions), ASTM D4327 (anion analysis in water), USP (conductivity of purified water), and EPA Methods 300.0, 300.1, and 6200 for regulated ion quantification. Full audit trail logging, role-based user permissions, electronic signatures, and 21 CFR Part 11–compliant data handling are embedded in the native chromatography data system (CDS), supporting GLP/GMP compliance in quality control laboratories.
Software & Data Management
WAYEAL’s proprietary CDS features a graphical instrument control interface with real-time parameter monitoring, automated calibration curve generation, peak integration using adaptive baseline algorithms, and customizable report templates (PDF, Excel, CSV). The software acquires up to four analog/digital channels simultaneously without external DAQ cards, minimizing signal noise and timing drift. Integrated database architecture ensures ACID-compliant storage, version-controlled method files, and full traceability of raw data, processed results, and audit events. Seamless expansion supports multidimensional IC (column-switching), IC-IC, and offline/online coupling with mass spectrometry platforms via standardized API interfaces.
Applications
- Environmental monitoring: Quantification of nitrate, sulfate, fluoride, and perchlorate in groundwater per EPA Method 314.1.
- Pharmaceutical QA/QC: Counter-ion profiling of APIs, residual acetate/formate in biologics, and chloride testing in parenteral solutions.
- Food & beverage: Lactate, citrate, and phosphate analysis in dairy products; iodide and thiocyanate in infant formula.
- Energy sector: Trace anion impurities (Cl⁻, F⁻, SO₄²⁻) in lithium-ion battery electrolytes and fuel cell membranes.
- Industrial chemistry: Speciation of Cr(VI) as chromate in plating baths using post-column UV derivatization.
FAQ
Does the IC6600 support regulatory-compliant data integrity?
Yes. The CDS implements full 21 CFR Part 11 functionality—including electronic signatures, immutable audit trails, and granular access controls—to meet FDA, EMA, and PMDA requirements.
Can the system perform simultaneous anion and cation analysis in one run?
Yes. With dual-channel detection and programmable valve switching, the IC6600 enables concurrent anion/cation determination using a single injection and two parallel columns.
Is column oven temperature uniformity validated across operating ranges?
The five-zone thermal management system maintains ±0.005 °C stability over 4–65 °C, verified per ISO/IEC 17025 calibration procedures.
What eluent types are supported by the built-in generator?
KOH (hydroxide), Na₂CO₃/NaHCO₃ (carbonate/bicarbonate), and methanesulfonic acid (MSA) eluents are available through interchangeable electrolytic cartridges.
How does the system handle complex sample matrices with high background conductivity?
On-line matrix elimination and large-volume injection with trap-column enrichment reduce interferences and extend linear dynamic range by up to 100-fold for challenging environmental extracts.

