WIGGENS PLASMA 22 Benchtop Centrifuge
| Brand | WIGGENS |
|---|---|
| Origin | Germany |
| Model | PLASMA 22 |
| Type | Benchtop Centrifuge |
| Max. Speed | 3000 rpm |
| Max. RCF | 1288 ×g |
| Capacity | 8 × 9/15 mL |
| Dimensions (W × D × H) | 280 × 275 × 410 mm |
| Noise Level | <60 dB(A) |
| Power Supply | 220–230 V, 50–60 Hz |
| Power Consumption | 120 W |
| Compliance | EN 61010-1, EN 61010-2-020, EN 61326-1, EN 61326-2-6, 2011/65/EU, 2012/19/EU, 2014/30/EU, 2014/35/EU, 98/79/EC |
Overview
The WIGGENS PLASMA 22 Benchtop Centrifuge is an engineered solution for low-speed, high-reproducibility separation of biological fluids—specifically optimized for plasma and platelet-rich plasma (PRP) preparation in clinical and regenerative medicine applications. Operating on the principle of sedimentation under controlled gravitational force (RCF), the PLASMA 22 delivers precise, repeatable centrifugation at up to 3000 rpm and 1288 ×g, enabling gentle yet effective separation of cellular components from whole blood without inducing hemolysis or platelet activation. Its design prioritizes operational safety, regulatory compliance, and seamless integration into GLP- and GMP-aligned workflows—particularly in dental surgery, wound healing, diabetic ulcer management, and burn therapy protocols where sterile, consistent PRP yield is clinically critical.
Key Features
- Intuitive LCD interface displaying real-time RPM, RCF, elapsed time, and remaining time
- Precise speed control in 50 rpm / 50 ×g increments with programmable acceleration and deceleration profiles (PCBS technology)
- 175 selectable ramp/dwell slope combinations to minimize sample resuspension and preserve stratified layers post-centrifugation
- 16 user-programmable memory slots supporting multi-step protocols with pause/resume capability
- Microprocessor-based control system with brushless DC motor ensuring maintenance-free operation and extended service life
- Automatic rotor identification and overspeed protection safeguarding against mechanical overloads
- Acoustic and visual status alerts—including end-of-run notification and fault indication—for unattended operation
- Energy-saving mode with auto-shutdown after idle timeout, configurable via front-panel settings
Sample Compatibility & Compliance
The PLASMA 22 accommodates standard conical tubes (9 mL and 15 mL) using its fixed-angle horizontal rotor (RT237), certified for autoclaving at 121°C, 2 bar for 20 minutes. All rotor components—including adapters—are constructed from medical-grade stainless steel (AISI 304) and fully compatible with ISO 13485-compliant sterilization cycles. The centrifuge chamber features a seamless stainless-steel interior and integrated thermal insulation layer between rotor housing and outer casing, meeting IEC 61010-2-020 requirements for protection against mechanical hazards and thermal exposure. It complies with EU In Vitro Diagnostic Medical Device Directive (98/79/EC), RoHS (2011/65/EU), WEEE (2012/19/EU), EMC (2014/30/EU), and Low Voltage Directive (2014/35/EU). Documentation supports audit readiness per FDA 21 CFR Part 11 when paired with validated software logs.
Software & Data Management
While the PLASMA 22 operates as a standalone instrument, its firmware architecture supports traceable parameter logging via optional RS-232 or USB data export (subject to local validation). All executed programs—including start/stop timestamps, final RCF, total run duration, and rotor ID—are retained in non-volatile memory for ≥10,000 cycles. Audit trail functionality meets basic GLP record-keeping expectations, and parameter recall ensures consistent reprocessing across shifts. Firmware updates are performed offline via secure USB key, preserving integrity during field deployment in regulated environments.
Applications
- Preparation of platelet-rich plasma (PRP) and platelet-poor plasma (PPP) from anticoagulated whole blood
- Isolation of fibrinogen, growth factors, and extracellular vesicles in tissue regeneration research
- Processing of bone marrow aspirates and adipose-derived stromal vascular fraction (SVF)
- Centrifugal washing of red blood cells prior to transfusion or diagnostic assays
- Routine sedimentation of urine, cerebrospinal fluid (CSF), and synovial fluid specimens
- Low-shear pelleting of sensitive primary cells and organoids in preclinical studies
FAQ
What is the maximum tube capacity supported by the PLASMA 22?
It accepts up to eight 9 mL or 15 mL conical centrifuge tubes using the included RT237 horizontal rotor.
Can the rotor be sterilized in an autoclave?
Yes—the RT237 rotor and all compatible adapters are autoclavable at 121°C, 2 bar for 20 minutes.
Does the centrifuge support real-time speed adjustment during operation?
Yes—RPM and RCF can be modified dynamically while running, with immediate feedback on the LCD display.
How does the imbalance detection system function?
Integrated vibration sensors continuously monitor rotational symmetry; automatic shutdown occurs within 0.5 seconds if imbalance exceeds 5 g·cm threshold.
Is the PLASMA 22 suitable for use in ISO Class 5 cleanrooms?
Its sealed motor housing, low particulate emission (<0.1 µm particle count ≤3,520/m³), and absence of oil-lubricated components meet ISO 14644-1 Class 5 operational criteria when installed with appropriate air filtration.
