Xiangyi GL-23M Floor-Standing High-Speed Refrigerated Centrifuge
| Brand | Xiangyi |
|---|---|
| Origin | Hunan, China |
| Manufacturer Type | Direct Manufacturer |
| Product Category | Domestic |
| Model | GL-23M |
| Instrument Type | Floor-Standing Centrifuge |
| Speed Range | 10,000–30,000 rpm (Max. 23,000 rpm) |
| Max. RCF | 60,460 × g |
| Max. Capacity | 4 × 1000 mL |
| Temperature Range | –20 °C to +40 °C |
| Dimensions (W×D×H) | 730 × 930 × 960 mm |
| Rotor Material | Forged 7075-T6 Aluminum Alloy |
| Display | 7-inch HD Touchscreen |
| Data Storage | Internal Logging for Months of Operation & Fault Records |
| Control Modes | Step Centrifugation, Scheduled Start, Sample ID Tagging, Curve Mode, Program Mode, Multi-Language UI (English, Chinese, Spanish, French) |
Overview
The Xiangyi GL-23M is a floor-standing high-speed refrigerated centrifuge engineered for demanding separation tasks in molecular biology, biochemistry, virology, and biopharmaceutical research laboratories. It operates on the principle of sedimentation under controlled gravitational force (RCF), leveraging precise temperature regulation (–20 °C to +40 °C) and rotational stability to isolate subcellular components—including organelles, nucleic acids, proteins, viruses, and bacterial cell lysates—with high reproducibility. Designed for routine and method-intensive workflows, the GL-23M supports large-volume processing up to 4 × 1000 mL per run, making it suitable for preparative-scale applications such as plasmid purification, exosome isolation, and vaccine development support.
Key Features
- Precision Refrigeration System: Dual-stage compressor with independent pre-cooling function ensures rapid temperature stabilization and tight thermal control (±1 °C) across the full operating range, critical for heat-sensitive biomolecules.
- Intelligent Rotor Recognition: Automatic detection of rotor type, maximum speed limit, and imbalance tolerance prevents operational errors and enforces safety-critical constraints at startup.
- 7-Inch HD Touch Interface: Real-time display of setpoints and actual values—including speed, RCF, time, temperature, and acceleration/deceleration profiles—on a single screen; supports gesture-based navigation and customizable home screens.
- Robust Mechanical Architecture: All aluminum rotors are forged from aerospace-grade 7075-T6 alloy and surface-treated with hard-anodized coating (≥25 µm thickness) for corrosion resistance and structural integrity under repeated high-RCF loads.
- Enhanced Safety Protocols: Comprehensive protection suite includes lid interlock, overspeed cutoff, real-time imbalance monitoring, emergency brake activation, and optional user-level access control (admin/operator/guest) compliant with GLP audit requirements.
- Tool-Free Rotor Installation: Patented drive shaft coupling enables secure rotor mounting without screws or alignment tools—reducing setup time and minimizing mechanical wear.
Sample Compatibility & Compliance
The GL-23M accommodates a broad spectrum of sample formats via interchangeable angular rotors (e.g., 6×500 mL, 4×1000 mL, 12×50 mL), compatible with standard polypropylene, polycarbonate, and stainless-steel centrifuge tubes. Its design meets IEC 61010-1:2010 safety standards for laboratory equipment and incorporates electromagnetic compatibility (EMC) shielding per EN 61326-1. While not certified for ISO 13485 or FDA 21 CFR Part 11 out-of-the-box, the instrument’s audit-ready data logging (with timestamped event records, operator IDs, and parameter change history) supports integration into GxP environments when deployed with validated SOPs and networked data export protocols.
Software & Data Management
Built-in firmware enables storage of ≥6 months of continuous operational logs—including run parameters, temperature profiles, fault codes, and maintenance alerts—without external media. Users can define and save >200 custom programs, each annotated with descriptive metadata (e.g., “HeLa nuclear extract – 23,000 rpm, 45 min, –8 °C”). Export options include USB transfer of CSV-formatted datasets for traceability and LIMS integration. The interface supports English, Chinese, Spanish, and French language packs, facilitating multi-site deployment in international academic and contract research organizations.
Applications
- Isolation of mitochondria, lysosomes, and microsomes from tissue homogenates
- Ultracentrifugal purification of extracellular vesicles and lipoprotein fractions
- Concentration of viral vectors (AAV, lentivirus) prior to downstream titration
- Clarification of recombinant protein expression supernatants
- Preparative separation of polymer nanoparticles and colloidal suspensions
- High-throughput sample preparation for next-generation sequencing library construction
FAQ
What is the minimum achievable temperature during operation?
The refrigeration system maintains stable setpoints from –20 °C to +40 °C; ambient temperature and rotor type influence cooling rate and final equilibrium temperature.
Can the GL-23M be integrated into a laboratory automation platform?
Yes—RS-232 and optional Ethernet interfaces support remote command execution and status polling via SCPI-compatible protocols, enabling coordination with robotic liquid handlers and scheduling systems.
Is rotor calibration required before first use?
No factory calibration is needed; however, users must verify rotor identification and confirm maximum speed limits match the installed rotor’s certified specifications per manufacturer documentation.
Does the instrument comply with energy efficiency regulations?
It meets China’s GB/T 30224-2013 energy labeling requirements for centrifuges and incorporates intelligent power management that reduces standby consumption by >40% versus legacy models.
How is data integrity ensured during long-duration runs?
All logged entries are written to non-volatile memory with cyclic redundancy checks (CRC); timestamps are synchronized to internal RTC with battery backup to prevent drift or loss during power interruption.
