Xiangyi HT165R Benchtop High-Speed Refrigerated Centrifuge

Overview

The Xiangyi HT165R is a high-performance benchtop refrigerated centrifuge engineered for precision separation of biomacromolecules—including proteins, nucleic acids, subcellular organelles, and viral particles—in research laboratories, clinical diagnostics, and quality control environments. Operating on the principle of sedimentation under controlled gravitational force (RCF), the HT165R delivers up to 26,054 × g at its maximum rotational speed of 16,500 rpm, enabling rapid and reproducible pelleting of low-volume samples in microcentrifuge tubes (0.2–5 mL) and PCR strips. Its compact footprint (320 × 590 × 270 mm) and low acoustic emission (<58 dB[A] at full speed) make it suitable for shared lab spaces and biosafety cabinets. The unit integrates dynamic refrigeration control—adjusting compressor output in real time based on rotor thermal load—to maintain precise temperature stability (±1 °C) across the operating range of –20 °C to +40 °C, minimizing sample denaturation during extended runs.

Key Features

• Dynamic refrigeration system with adaptive compressor modulation ensures consistent thermal management without overshoot or energy waste.
• 5-inch high-resolution capacitive touchscreen interface displays all critical parameters—speed, RCF, time, temperature, acceleration/deceleration profile, and rotor ID—in a single view.
• 11 programmable acceleration and 12 deceleration profiles—including 10 user-definable curves—optimize pelleting integrity and prevent resuspension of sensitive precipitates.
• Dedicated PULSE mode enables transient centrifugation (≤30 s) for quick pellet collection prior to full protocol execution.
• Multi-mode timing: start-time, run-at-speed, and continuous operation modes support diverse experimental workflows; timer resolution supports either 99 h 59 min or 99 min 59 s formats.
• Programmable pre-cooling function with auto-save capability allows users to initiate chamber cooldown before sample loading, reducing thermal shock and improving reproducibility.
• Automatic door lock mechanism engages upon lid closure; integrated safety interlocks prevent operation unless rotor is correctly seated and lid fully sealed.
• Comprehensive rotor recognition via embedded RFID or mechanical coding prevents unauthorized or mismatched rotor use and enforces speed/temperature limits per rotor type.
• Robust construction: 316 stainless steel inner chamber resists corrosion from condensate and chemical splashes; rotors fabricated from aerospace-grade 7075-T6 aluminum alloy with hard-anodized surface for enhanced durability and fatigue resistance.

Sample Compatibility & Compliance

The HT165R accommodates eight interchangeable rotors—including fixed-angle (e.g., 24 × 1.5 mL), horizontal swing-out (for 48 × 1.5 mL), and PCR strip carriers—supporting volumes from 0.2 mL to 5 mL. It complies with IEC 61010-1:2010 for laboratory equipment safety and meets electromagnetic compatibility requirements per EN 61326-1. While not certified for GMP manufacturing environments, its programmable protocols, audit-ready parameter logging, and repeatable performance align with GLP principles for non-clinical laboratory studies. Temperature accuracy and RCF consistency are validated per ISO 21501-4 for particle characterization instrumentation where applicable.

Software & Data Management

All operational parameters—including speed, time, temperature, acceleration/deceleration profiles, and rotor ID—are logged automatically per run and stored internally (≥1,000 cycle history). Data export is supported via USB port in CSV format for integration into LIMS or statistical analysis platforms. No proprietary software installation is required; however, optional firmware updates are distributed through Xiangyi’s secure technical portal. The system supports 21 CFR Part 11–compatible audit trails when operated with external timestamped logging systems, though native electronic signature functionality is not embedded.

Applications

• Purification of plasmid DNA, genomic DNA, and RNA from bacterial lysates and mammalian cells.
• Isolation of exosomes and extracellular vesicles from cell culture supernatants and biofluids.
• Clarification of protein expression lysates prior to chromatography or electrophoresis.
• Preparative centrifugation of enzyme assays, immunoassays, and ELISA plate wash steps.
• Routine QC of vaccine formulations, monoclonal antibody preparations, and nanoparticle suspensions.
• High-throughput processing of PCR plates and qPCR reaction tubes in molecular diagnostics labs.

FAQ

What is the minimum and maximum operating temperature range?
The HT165R maintains chamber temperatures from –20 °C to +40 °C, with ±1 °C accuracy at setpoint under standard ambient conditions (20–25 °C).
Does the centrifuge support rotor-specific speed limits?
Yes—rotor identification is enforced via mechanical coding and/or embedded identifiers; the controller restricts maximum speed and temperature based on each rotor’s certified specifications.
Can multiple users store individual programs securely?
Up to 100 user-defined programs can be saved with descriptive naming; no password protection or role-based access is implemented natively.
Is remote monitoring or network connectivity available?
No Ethernet or Wi-Fi interface is included; data transfer occurs exclusively via USB flash drive.
What maintenance intervals are recommended for long-term reliability?
Annual inspection of refrigerant pressure, compressor performance, and rotor balance is advised; routine cleaning of condenser coils and chamber interior is required every 3 months under continuous use.