Xiangyi L550 Benchtop Low-Speed High-Capacity Centrifuge
| Brand | Xiangyi |
|---|---|
| Origin | Hunan, China |
| Manufacturer Type | Direct Manufacturer |
| Product Category | Domestic |
| Model | L550 |
| Instrument Type | Benchtop Centrifuge |
| Speed Range | 0–5500 rpm |
| Max RCF | 5310 × g |
| Max Capacity | 4 × 500 mL (horizontal rotor) |
| Dimensions (W×D×H) | 470 × 560 × 380 mm |
| Rotor Configuration | Horizontal swing-out rotor |
| Application Tier | Cell & bacterial separation |
| Acceleration Profiles | 9 programmable ramp curves |
| Deceleration Profiles | 10 programmable brake curves |
| Safety Features | Overspeed protection, overtemperature protection, lid interlock, dual-stage damping system |
Overview
The Xiangyi L550 is a benchtop low-speed centrifuge engineered for routine separation tasks in clinical laboratories, cell culture facilities, and biomedical research settings. It operates on the principle of sedimentation under controlled gravitational force (RCF), enabling efficient pelleting of cells, bacteria, whole blood components, and other suspended particulates without compromising structural integrity or viability. Designed for stability and operational consistency at moderate rotational speeds, the L550 avoids high-shear stress associated with ultracentrifugation—making it ideal for applications requiring gentle yet reproducible separation outcomes. Its robust cast-aluminum housing, precision-balanced horizontal rotor assembly, and sealed brushless AC frequency-controlled motor ensure long-term mechanical reliability and minimal maintenance intervention.
Key Features
- Brushless AC frequency-controlled motor: Delivers high torque output across the full speed range (0–5500 rpm), eliminates carbon brush wear, and prevents contamination from particulate shedding—critical for cleanroom-adjacent workflows.
- Intelligent RCF calculation and real-time display: Automatically converts user-input RPM to relative centrifugal force (×g) based on rotor radius, supporting method standardization across multi-user environments.
- Programmable operation: Stores multiple pre-set protocols with independent time, speed, acceleration, and deceleration parameters—facilitating repeatable execution of SOPs in GLP-compliant labs.
- Dual-stage damping system: Integrates mechanical and fluidic damping elements to suppress vibration during deceleration, minimizing resuspension of sedimented pellets and improving recovery yield.
- Comprehensive safety architecture: Includes lid interlock switch, overspeed detection, thermal cutoff sensor, and automatic rotor recognition logic (when used with certified Xiangyi rotors).
- Ergonomic design: Front-accessible rotor chamber, intuitive membrane keypad interface, and compact footprint (470 × 560 × 380 mm) optimize bench space utilization in high-density lab configurations.
Sample Compatibility & Compliance
The L550 supports standard 500 mL conical centrifuge bottles (e.g., Falcon-style) via its 4-position horizontal rotor configuration, accommodating common tube formats including 15 mL, 50 mL, and 100 mL polypropylene or glass vessels using optional adapters. It meets IEC 61010-1:2010 safety requirements for laboratory electrical equipment and conforms to GB/T 13789–2019 (Chinese national standard for centrifuges). While not certified for ISO 13485 or FDA 21 CFR Part 11 out-of-the-box, its programmable memory and audit-ready parameter logging support alignment with internal quality management systems adhering to ISO/IEC 17025 and CLIA guidelines.
Software & Data Management
The L550 features embedded firmware with non-volatile memory capable of storing ≥10 user-defined protocols. All run parameters—including start/stop timestamps, final speed, actual RCF, and error logs—are retained in device memory for post-run review. Though it does not include PC connectivity or proprietary software, its serial port interface (RS-232) enables integration with third-party lab information systems (LIS) or custom data acquisition scripts. Protocol export/import functionality is available via optional USB dongle module (sold separately), supporting CSV-formatted method transfer and version-controlled procedure archiving.
Applications
- Clinical hematology: Separation of whole blood into plasma, buffy coat, and erythrocyte layers for diagnostic assays.
- Cell culture harvesting: Gentle pelleting of adherent and suspension mammalian cells prior to lysis or passaging.
- Microbiology: Concentration of bacterial cultures from liquid media for downstream plating, staining, or genomic extraction.
- Biofluid processing: Clarification of serum, urine, cerebrospinal fluid (CSF), and ascites samples prior to immunoassay or electrophoresis.
- Vaccine and bioprocess development: Intermediate clarification steps in upstream biomanufacturing workflows where high-speed shear must be avoided.
FAQ
What is the maximum rated capacity for the L550 centrifuge?
The L550 supports a maximum load of four 500 mL tubes when equipped with the standard horizontal rotor (part no. L550-HR4). Tube compatibility extends to smaller volumes using optional angle or bucket adapters.
Does the L550 meet international electromagnetic compatibility (EMC) standards?
Yes—the unit complies with IEC 61326-1:2013 for EMC emissions and immunity in laboratory environments.
Can the L550 be validated for GMP use?
While the base instrument lacks factory-issued IQ/OQ documentation, its stable control architecture, parameter traceability, and configurable safety thresholds allow for site-specific qualification per Annex 15 and USP guidelines.
Is rotor imbalance detection built into the system?
The L550 includes dynamic imbalance sensing that halts operation if vibration exceeds predefined thresholds during acceleration or steady-state rotation.
What maintenance intervals are recommended for routine operation?
No scheduled motor servicing is required due to the brushless design; however, quarterly inspection of rotor threads, lid seal integrity, and calibration of speed/RCF display against NIST-traceable tachometer is advised.
