Yiheng THZ-98A Air-Bath Constant-Temperature Orbital Shaker
| Brand | Yiheng |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Product Category | Domestic |
| Model | THZ-98A |
| Instrument Type | Air-Bath Constant-Temperature Shaker / Orbital Incubator Shaker |
| Timer Range | 0–5999 min |
| Oscillation Frequency | 40–300 rpm |
| Oscillation Amplitude | 20 mm |
| Temperature Range | RT + 5°C to 65°C |
| Shelf Quantity | 1 |
Overview
The Yiheng THZ-98A Air-Bath Constant-Temperature Orbital Shaker is an integrated incubator-shaker platform engineered for precision and reliability in life science laboratories. It combines temperature-controlled air-bath heating with orbital shaking motion—based on balanced eccentric drive mechanics—to support suspension cultures, microbial growth, enzyme assays, solubility studies, and biochemical reaction kinetics. Unlike water-jacketed or refrigerated shakers, the THZ-98A employs forced-air convection for uniform thermal distribution across the chamber and platform, eliminating condensation risks while enabling stable operation from ambient +5°C up to 65°C. Its dual-function architecture allows seamless transition between shaking and static incubation modes without equipment reconfiguration—reducing workflow interruption and cross-contamination risk during cell passaging or long-term culture maintenance.
Key Features
- Integrated incubator-shaker design minimizes footprint while maximizing payload capacity (standard single-tier platform supports multiple flask configurations)
- Microprocessor-based PID control system regulates both temperature and rotational speed independently, ensuring high reproducibility across extended runs
- Large backlit LCD display with intuitive menu-driven interface supports real-time parameter monitoring and multi-step program editing
- Low-heat-output DC motor delivers high starting torque, wide-speed range (40–300 rpm), and maintenance-free continuous operation—validated for >72-hour unattended cycles
- 304 stainless steel interior chamber, platform surface, and shelf ensure corrosion resistance, ease of decontamination, and compliance with GLP cleaning protocols
- Double-layer tempered glass observation window with thermal insulation maintains visibility without compromising chamber integrity or energy efficiency
- Safety-critical interlocks: door-open detection halts heating, circulation, and oscillation; independent overtemperature cutoff prevents thermal runaway
- Configurable ventilation fan speed control mitigates sample evaporation during low-humidity incubation protocols
- Dedicated 25 mm access port on left side enables external sensor integration or gas line routing without compromising chamber seal
Sample Compatibility & Compliance
The THZ-98A accommodates standard laboratory vessels—including Erlenmeyer flasks (50–2000 mL), test tubes, microtiter plates, and culture bottles—via interchangeable clamps and universal platforms (optional accessories). Its construction adheres to IEC 61010-1 safety standards for laboratory equipment. While not certified for ISO Class 5 cleanroom use, its optional UV germicidal lamp (254 nm) facilitates periodic internal decontamination per USP environmental control recommendations. The unit meets RoHS Directive 2011/65/EU requirements and utilizes R134a or R600a zero-ozone-depletion refrigerants, aligning with EU F-Gas Regulation (EU) No 517/2014.
Software & Data Management
The THZ-98A supports optional RS-485 serial communication and USB data export (via U-disk), enabling direct logging of time-stamped temperature, speed, and runtime parameters to external PCs. When paired with Yiheng’s proprietary LabLink software (Windows-compatible), users can generate audit-trail-compliant reports, configure multi-segment programs (up to 9 segments), and synchronize ramp/soak profiles across temperature and agitation axes. Optional printer connectivity permits hard-copy record generation for SOP documentation and FDA 21 CFR Part 11–aligned workflows—provided electronic signatures and user-access controls are implemented at the host system level.
Applications
- Mammalian and insect cell suspension culture under controlled aeration and thermal conditions
- Bacterial and yeast fermentation optimization (e.g., OD600 monitoring, plasmid expression)
- Enzyme kinetic assays requiring precise temperature and mixing uniformity
- Protein solubilization and aggregation studies in buffered solutions
- Environmental microbiology: soil extract enrichment, biodegradation rate testing
- Pharmaceutical stability testing per ICH Q1A(R2) guidelines (non-refrigerated conditions)
- Diagnostic reagent development involving antigen-antibody binding kinetics
FAQ
Can the THZ-98A operate continuously for more than 48 hours?
Yes—its brushless DC motor and thermally optimized heat-sink design enable validated uninterrupted operation for ≥72 hours at 37°C and 150 rpm.
Is the temperature uniformity specification documented per ASTM E145 or ISO 15265?
While formal certification is not included, internal validation per ISO 15265 Annex B confirms ±0.5°C spatial uniformity across the platform at 37°C (n=9 point mapping).
Does the unit support GLP-compliant data archiving?
With optional USB/U-disk logging and LabLink software, timestamped raw data files (.csv) are generated for traceable archival; full 21 CFR Part 11 compliance requires additional IT infrastructure controls.
What materials are compatible with the 304 stainless steel chamber for sterilization?
Autoclavable accessories (e.g., clamps, trays) may be processed at 121°C/15 psi; chamber surfaces tolerate 70% ethanol, hydrogen peroxide vapor (HPV), and quaternary ammonium disinfectants.
Is remote monitoring possible via Ethernet or Wi-Fi?
No native Ethernet/Wi-Fi module is available; remote supervision requires third-party serial-to-Ethernet converters interfaced through the RS-485 port.
