Zhicheng ZXSD-1160 Advanced Fully Automated Biochemical Incubator

Overview

The Zhicheng ZXSD-1160 Advanced Fully Automated Biochemical Incubator is a precision-engineered environmental control system designed for stable, reproducible cultivation of microorganisms, cell cultures, and biological samples under tightly regulated thermal conditions. Based on forced convection air circulation architecture, the incubator maintains uniform temperature distribution across its 160 L working chamber—critical for applications requiring compliance with GLP, ISO 17025, and USP environmental monitoring protocols. Its core control system integrates an environment-scanning microprocessor chip with a high-response thick-film thermal sensor, enabling real-time feedback correction and minimizing thermal drift. The unit operates across a wide range of 4–65 °C with 0.1 °C resolution, supporting both low-temperature microbial preservation and elevated-temperature enzymatic or fermentation studies. Designed for continuous operation in laboratory environments with ambient temperatures between 5–35 °C, the ZXSD-1160 incorporates a CFC-free refrigeration circuit and passive thermal insulation optimized for energy efficiency without compromising stability.

Key Features

• Forced convection airflow system with rear-mounted centrifugal fan and perforated stainless steel rear wall for optimal thermal homogeneity (≤±1 °C uniformity)
• Nano-coated antibacterial stainless steel interior chamber and electropolished adjustable shelving—resistant to corrosion and compatible with routine sterilization protocols including 70% ethanol wipe-downs and UV decontamination cycles
• Double-layer door assembly featuring inner insulated glass and outer tempered safety glass—minimizing heat loss while maintaining clear visual access during operation
• Integrated LED display interface with intuitive touch-sensitive controls; supports real-time toggling between setpoint, measured temperature, elapsed time, and system clock
• Automated defrost cycle triggered by evaporator frost accumulation detection—ensures uninterrupted low-temperature operation down to 4 °C
• Dual-limit temperature tracking logic with independent upper/lower thresholds; activates audible alarm, flashing LED indicator, and automatic cut-off of heating or cooling output upon deviation
• Built-in digital temperature calibration offset function—enables traceable field adjustment to align displayed values with NIST-traceable reference thermometers
• Power failure recovery mode: resumes previous operational parameters automatically upon grid restoration, preserving experimental continuity
• 100-hour programmable timer with end-of-cycle shutdown and optional hold mode for scheduled maintenance windows
• Internal 220 V AC power outlet and LED illumination—facilitating integration of peripheral devices such as shakers or pH monitors within the chamber

Sample Compatibility & Compliance

The ZXSD-1160 accommodates standard microbiological culture vessels—including Petri dishes, test tubes, flasks, and multiwell plates—within its geometrically optimized cavity. The mirror-finish, radius-cornered interior minimizes dust accumulation and simplifies cleaning validation per ISO 14644-1 Class 7 cleanroom maintenance standards. Its construction meets IEC 61010-1:2010 safety requirements for laboratory equipment, and its refrigerant-free cooling system complies with EU F-Gas Regulation (EU) No 517/2014 and EPA SNAP program guidelines. While not certified for medical device manufacturing under ISO 13485, the incubator’s parameter logging capability and hardware-level alarm interlocks support audit readiness for GMP-aligned QC laboratories performing environmental monitoring per Annex 1 (EU) and FDA Guidance for Industry on Sterile Drug Products.

Software & Data Management

The ZXSD-1160 operates via embedded firmware without external PC dependency; however, it supports optional RS-485 serial communication (Modbus RTU protocol) for integration into centralized laboratory information management systems (LIMS). All temperature setpoints, alarms, timer events, and calibration offsets are stored in non-volatile memory with write-protection logic to prevent accidental modification. Audit trail functionality—including timestamped records of parameter changes, alarm activations, and power interruptions—is available via optional data logger module compliant with FDA 21 CFR Part 11 requirements when paired with validated third-party software. The system does not include cloud connectivity or proprietary cloud platforms.

Applications

• Microbial culture maintenance and strain preservation at defined sub-ambient or mesophilic temperatures
• Biochemical assay incubation for enzyme kinetics, substrate metabolism, and antibiotic susceptibility testing (e.g., CLSI M07-A10)
• Cell-based toxicity screening and proliferation assays requiring precise thermal control
• Environmental simulation for agricultural research—including seed germination, fungal growth, and soil microbe activity studies
• Quality control testing of pharmaceutical excipients and raw materials under ICH Q1A(R2) stability storage conditions
• Regulatory-compliant storage of reference standards and working solutions in analytical laboratories

FAQ

What is the minimum operating temperature, and can it maintain 4 °C continuously?
Yes—the ZXSD-1160 achieves and sustains 4 °C with ≤±0.5 °C fluctuation using its adaptive refrigeration control algorithm and automatic defrost management.
Is the interior lighting UV-compatible for use with light-sensitive cultures?
The built-in LED lamp emits no ultraviolet radiation and is suitable for photophobic organisms; however, users requiring full dark-cycle control may disable illumination via the main menu.
Can the incubator be validated for IQ/OQ/PQ protocols?
Yes—its digital calibration interface, alarm log history, and stable thermal performance enable qualification per ASTM E2500-13 and ISPE Good Practice Guide for Equipment Qualification.
Does it support remote monitoring or Ethernet connectivity?
No native Ethernet or Wi-Fi interface is included; RS-485 Modbus integration requires external gateway hardware and configuration by qualified personnel.
What is the maximum load capacity per shelf, and are additional shelves available?
Each electropolished stainless steel shelf supports up to 15 kg uniformly distributed; up to two additional shelves (part number ZXSD-SH-02) may be installed, bringing total capacity to four shelves.