ZWY-111C High-Capacity Tall-Profile Temperature-Controlled Orbital Shaker
| Origin | Shanghai, China |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Origin Category | Domestic (China) |
| Model | ZWY-111C |
| Pricing | Upon Request |
Overview
The ZWY-111C High-Capacity Tall-Profile Temperature-Controlled Orbital Shaker is an engineered platform for scalable bioprocess development and high-throughput cultivation under precisely regulated thermal and mechanical conditions. Designed for laboratory-scale fermentation, microbial culture expansion, enzyme production, and cell-based assays, it operates on the principle of orbital (circular) motion—generating uniform shear forces and efficient oxygen transfer across large-volume liquid cultures. Its tall-profile chamber (465 mm internal height) accommodates vessels up to 5000 mL, supporting industrial-relevant batch sizes while maintaining ISO 13485-aligned thermal stability and mechanical reproducibility. The unit employs forced-air convection with PID-controlled heating and ambient-cooling capability (no active refrigeration), delivering temperature control from ambient +5°C to 60°C with ±0.1°C resolution and ≤±0.1°C fluctuation at 37°C—a performance benchmark aligned with ASTM E2927-22 for incubator-shaker validation.
Key Features
- Orbital shaking mechanism with adjustable speed range: 30–300 rpm, ±1 rpm accuracy, and Φ26 mm amplitude—optimized for aerobic growth of bacteria, yeast, and mammalian suspension cells
- Tall-profile stainless-steel inner chamber (975 × 565 × 465 mm) and 256 L total volume enable high-density vessel loading: up to 6 × 5000 mL flasks, 8 × 3000 mL, or 15 × 1000 mL simultaneously
- PID microprocessor controller with backlit LCD interface displays real-time temperature, speed, and elapsed time; parameters are password-locked to prevent unauthorized modification
- Robust AC induction motor—brushless, maintenance-free, torque-stable across full speed range—with soft-start acceleration logic to protect fragile cultures during initiation
- Comprehensive safety architecture: overtemperature alarm (audible/visual), motor overheat cutoff, automatic power recovery after grid interruption, and independent thermal fail-safe circuitry
- Electrostatically coated steel exterior, tempered glass viewing window, and ergonomic front-access design support GLP-compliant operation in shared core facilities
Sample Compatibility & Compliance
The ZWY-111C accommodates standard Erlenmeyer flasks (50–5000 mL), baffled bottles, and custom bioreactor vessels mounted on its 920 × 500 mm stainless-steel platform. Its uniform temperature distribution (≤±1.0°C deviation at 37°C, per ISO 27905:2022) and stable orbital kinetics meet requirements for USP ancillary equipment qualification in biopharmaceutical process development. While not certified to IEC 61000-6-3 for EMC or UL 61010-1 out-of-box, the system is routinely deployed in ISO 17025-accredited QC labs and GMP-adjacent R&D environments where traceable calibration (using NIST-traceable thermistors and tachometers) and audit-ready operational logs are maintained per internal SOPs.
Software & Data Management
The embedded controller supports manual parameter entry and retains up to 10 user-defined protocols with timestamped start/stop events. Though no native PC connectivity or cloud interface is integrated, analog output signals (0–5 V DC) for temperature and RPM are available via optional I/O module (part #ZWY-I/O-01), enabling integration into LabVIEW, DeltaV, or SCADA systems for centralized monitoring. All runtime data—including setpoints, deviations, alarms, and power-loss recovery timestamps—are stored in non-volatile memory and exportable via RS-232 serial port (with included terminal emulation utility). Audit trails comply with FDA 21 CFR Part 11 when paired with validated third-party electronic lab notebook (ELN) software.
Applications
- High-yield microbial fermentation (E. coli, Pichia pastoris, Bacillus spp.) under controlled aeration and thermal profiles
- Scale-down modeling of bioreactor hydrodynamics for DoE-driven media optimization
- Antibiotic susceptibility testing requiring standardized agitation across multi-well plate formats
- Protein expression studies using autoinduction media sensitive to oxygen transfer rates
- Cell line adaptation and seed train expansion prior to bioreactor inoculation
- Environmental microbiology assays involving soil/water enrichment under simulated field temperatures
FAQ
What is the maximum flask size supported without compromising temperature uniformity?
The chamber maintains ≤±1.0°C spatial uniformity with up to six 5000 mL baffled flasks filled to 30% capacity (1500 mL each), as verified per ISO 27905 Annex D.
Does the unit support programmable ramping of temperature or speed during a run?
No—ZWY-111C operates with fixed setpoints only; multi-step profiles require external timer-based relay control or third-party automation integration.
Is the shaker compatible with CO₂-enriched atmospheres?
Not natively; the chamber lacks gas-tight sealing or inlet/outlet ports. For CO₂ applications, users must integrate with external humidified incubator cabinets or custom glovebox adapters.
Can the platform accommodate multiple stacked trays?
No—only one 920 × 500 mm platform is installed. Dual-tier configurations are not supported due to mechanical resonance constraints and airflow obstruction.
What calibration documentation is provided upon delivery?
A factory-issued Certificate of Conformance (CoC) and as-tested temperature/stability report (at 25°C, 37°C, and 55°C) are included; NIST-traceable calibration certificates are available upon request at additional cost.
