KEWLAB CPS-L350 Peristaltic Pump

Overview

The KEWLAB CPS-L350 Peristaltic Pump is an engineered solution for precise, contamination-free fluid transfer in analytical, bioprocessing, and quality control laboratories. Based on the principle of peristalsis—where rollers compress flexible tubing to generate positive displacement—the CPS-L350 delivers repeatable volumetric flow without internal wetted parts, eliminating risk of cross-contamination and simplifying cleaning validation. Its design prioritizes operational reliability under variable load conditions, with a robust brushless DC motor and precision-machined rotor assembly ensuring long-term torque consistency across the full speed range (0.1–350 rpm). The pump supports both continuous and time-gated dispensing protocols, making it suitable for integration into automated sample preparation workflows, reagent delivery systems, and continuous monitoring loops.

Key Features

• 3.2-inch industrial-grade true-color LCD display with intuitive menu navigation and real-time visualization of speed, flow rate (calculated), elapsed time, and timer countdown.
• Ultra-low-noise operation (<45 dB[A] at 1 m distance) achieved through optimized gear train damping, vibration-isolated motor mounting, and acoustic enclosure design—critical for noise-sensitive environments such as cleanrooms and shared lab spaces.
• Programmable timer function spanning 0.1 seconds to 9999 hours, enabling unattended batch processing, timed infusions, or duty-cycle modulation for extended experiments.
• Dual-voltage compatibility (AC 110 V ±10% / AC 220 V ±10%, 50/60 Hz) and wide-input EMI filtering ensure stable performance in labs with fluctuating grid conditions or proximity to high-frequency instrumentation.
• Drop-in tube loading mechanism with calibrated roller gap adjustment accommodates standard peristaltic tubing sizes (ID 0.5–6.4 mm), supporting common silicone, Viton®, and Tygon® formulations.
• Non-volatile memory retains user-defined settings—including speed, direction, timer configuration, and external control mode—after power interruption, complying with GLP documentation requirements for parameter traceability.

Sample Compatibility & Compliance

The CPS-L350 is compatible with a broad spectrum of chemically resistant, USP Class VI-certified tubing materials, including silicone elastomers (for general aqueous solutions), fluoropolymer-lined tubing (for organic solvents and aggressive acids/bases), and pharma-grade thermoplastic elastomers (TPE) compliant with ISO 10993-5 cytotoxicity standards. Its pressure rating—0.1 MPa at minimum tubing wall thickness (0.86 mm) and up to 0.27 MPa at maximum (2.4 mm)—enables use in moderate-backpressure applications such as inline filtration, column elution, or gravity-compensated transfer. While not certified to IEC 61000-6-2/6-4 for EMC or UL/CSA safety marks, its IP31-rated enclosure meets basic protection against vertically falling drips and solid objects >2.5 mm, aligning with typical laboratory environmental classification per ISO 14644-1 Class 8 (100,000) cleanroom support infrastructure.

Software & Data Management

The pump supports bidirectional serial communication via RS232 and RS485 interfaces using ASCII-based command protocol, enabling seamless integration with LabVIEW, MATLAB, Python (pySerial), or custom SCADA platforms. Standard analog input (0–5 V) allows direct speed modulation from external sensors or PLCs; optional 0–10 V or 4–20 mA inputs facilitate connection to process controllers conforming to ISA-50.00.01 analog signal standards. All serial transactions are timestamped and logged locally upon request, supporting audit trails required under FDA 21 CFR Part 11 when deployed within validated computerized systems. Firmware updates are performed via UART bootloader, ensuring field-upgradability without hardware replacement.

Applications

• Automated liquid handling in HPLC mobile phase delivery and fraction collector triggering.
• Controlled feeding of cell culture media or nutrient solutions in bioreactor auxiliary systems.
• Calibration standard delivery in water quality analyzers (e.g., COD, TOC, phosphate meters).
• Low-shear transfer of shear-sensitive biological samples—including whole blood, microcapsules, and hydrogels—preserving structural integrity.
• In-line sampling for continuous emission monitoring systems (CEMS) and industrial effluent analysis.
• QC/QA workflows requiring documented flow repeatability per ASTM D1298 (density) or ISO 3104 (kinematic viscosity) preparatory steps.

FAQ

What tubing sizes are supported by the CPS-L350?
The pump accommodates inner diameters from 0.5 mm to 6.4 mm, corresponding to common peristaltic tubing standards such as PharMed® BPT, Masterflex® L/S®, and Cole-Parmer® Norprene®.
Is the CPS-L350 suitable for sterile applications?
Yes—when paired with gamma-sterilizable tubing and operated in laminar-flow hoods or isolators, the pump satisfies ISO 13485-aligned processes; however, end-user sterilization validation remains the responsibility of the system integrator.
Can the pump be integrated into a GMP-compliant environment?
It supports critical GMP elements—including parameter lockout, electronic log generation, and non-volatile setting retention—but final qualification (IQ/OQ/PQ) must be executed per site-specific protocols and Annex 11 guidance.
Does the CPS-L350 support pulse-free flow?
While all peristaltic pumps exhibit inherent pulsatility, the CPS-L350’s 12-roller head and high-resolution speed control (0.01 rpm) minimize flow variation to <±3% CV under steady-state conditions with appropriate tubing selection.
What is the expected service life of the drive motor?
Rated for >20,000 hours of continuous operation at rated load, based on accelerated life testing per IEC 60068-2-64, assuming ambient temperature ≤35 °C and regular roller/tubing maintenance.