ZWY-111D Foot-Operated Large-Capacity Temperature-Controlled Orbital Shaker

Overview

The ZWY-111D Foot-Operated Large-Capacity Temperature-Controlled Orbital Shaker is an engineered solution for scalable bioprocess development and high-throughput biological culture applications. Designed around orbital (circular) motion dynamics with precise temperature regulation, it operates on the principle of controlled convection-driven heat transfer and uniform rotational agitation—enabling consistent oxygen transfer, suspension homogeneity, and thermal stability critical for microbial growth, cell culture expansion, and enzymatic reaction kinetics. Its 286 L chamber volume and optimized airflow architecture support reproducible incubation across diverse vessel formats—from 100 mL flasks to 5 L bioreactors—making it suitable for pilot-scale fermentation, QC batch testing, and GLP-compliant upstream processing workflows in pharmaceutical, academic, and industrial life science laboratories.

Key Features

• Foot-actuated lid mechanism: Enables hands-free access during active operation—critical when handling multiple culture vessels or wearing gloves under biosafety conditions.
• PID-controlled microprocessor system with environmental scanning algorithm: Delivers real-time adaptive compensation for ambient drift, ensuring thermal stability within ±0.1 °C at 37 °C setpoint.
• Large-capacity orbital platform (940 × 584 mm): Supports up to six 5 L flasks or 82 × 100 mL vessels simultaneously, with Φ26 mm orbit diameter for optimal mixing efficiency and shear-sensitive cell viability.
• Brushless AC induction motor: Provides continuous operation across 30–300 rpm range with ±1 rpm speed accuracy, zero maintenance, and extended service life under sustained load.
• Forced-air convection system: Ensures uniform temperature distribution (≤±1 °C deviation at 37 °C) throughout the entire 1005 × 655 × 435 mm stainless-steel inner chamber.
• Intelligent safety architecture: Includes overtemperature cutoff (with independent thermal fuse), motor overheat protection, power-fail recovery, and programmable alarm escalation (audible + visual).
• Lockable parameter interface: Prevents unauthorized modification of setpoints; retains user-defined configurations—including 500-hour timer presets—after power interruption.

Sample Compatibility & Compliance

The ZWY-111D accommodates standard Erlenmeyer flasks (100–5000 mL), baffled bottles, roller bottles, and custom bioreactor vessels compatible with orbital agitation. Its chamber geometry and airflow path are validated for ISO 13485-aligned manufacturing environments and support documentation required for FDA 21 CFR Part 11–compliant data integrity protocols when integrated with external audit-trail-enabled software. Temperature and speed performance meet ASTM E1249 (Standard Practice for Performance Testing of Incubators) and ISO 20387 (Biobanking requirements) reference conditions for biological sample stability testing.

Software & Data Management

While the ZWY-111D features a standalone LCD interface (backlit, 128 × 64 pixel resolution) for local parameter display and adjustment, it supports optional RS-485/Modbus RTU connectivity for integration into centralized laboratory information management systems (LIMS) or SCADA platforms. All operational logs—including start/stop timestamps, temperature ramp profiles, speed deviations, and alarm events—are timestamped and stored internally for ≥30 days. When paired with validated third-party software, the unit enables electronic record generation compliant with ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available) per ICH GCP and EU Annex 11 guidance.

Applications

• Bacterial and yeast fermentation studies requiring scalable aeration and thermal consistency
• Mammalian and insect cell line expansion under controlled O₂/CO₂-balanced environments (when used with gas-compatible enclosures)
• Enzyme activity assays, protein expression optimization, and metabolic pathway analysis
• Antibiotic susceptibility testing, phage propagation, and vaccine seed train preparation
• Environmental microbiology sampling incubation and water quality bioassays
• Food safety validation (e.g., pathogen enrichment per ISO 6579-1) and probiotic stability profiling

FAQ

What is the maximum recommended operating temperature and its stability specification?
The unit maintains temperatures from ambient +5 °C to 60 °C, with a resolution of 0.1 °C and a typical fluctuation of ≤±0.1 °C at 37 °C under steady-state conditions.
Does the shaker include refrigeration capability?
No—the ZWY-111D is a heating-only system; cooling functionality requires external chillers or integration with a separate refrigerated incubator.
Is the foot pedal mechanism mechanically or electronically actuated?
It employs a pneumatic-assisted mechanical linkage, eliminating reliance on solenoids or external power for lid actuation—ensuring fail-safe operation during utility outages.
Can multiple shaking platforms be installed?
No—this model is configured with a single fixed platform; multi-tier configurations require the ZWY-211D series or custom-engineered variants.
What electrical safety certifications does the unit carry?
It complies with GB 4793.1–2019 (Chinese equivalent of IEC 61010-1) for laboratory equipment safety and meets EMC requirements per GB/T 18268.1–2010.