Sartorius Secura Series Analytical Balance

Overview

The Sartorius Secura Series Analytical Balance is a high-precision, ISO/IEC 17025-aligned gravimetric instrument engineered for reproducible mass measurement in regulated laboratory environments. Built on Sartorius’ decades of metrological expertise in mass metrology, the Secura implements advanced electromagnetic force compensation (EMFC) technology to deliver stable, drift-compensated readings at 0.01 mg readability across its 60 g capacity range. Its core architecture integrates isoCAL® — an internal, motor-driven, temperature- and time-triggered automatic calibration system — ensuring continuous traceability without manual intervention. Designed specifically for compliance-critical workflows, the Secura meets fundamental requirements of USP <41> for minimum weight validation, supports GLP and GMP documentation integrity through embedded audit trails, and provides full alignment with ISO 9001 quality management systems. The balance operates within a thermally stabilized draft enclosure featuring electrostatically treated glass panels, minimizing environmental perturbations from air currents and static charge accumulation — critical for low-mass measurements below 10 mg.

Key Features

• Full-color capacitive touchscreen interface with intuitive icon-based navigation and multi-language support (12 languages including English, German, Japanese, and Chinese)
• isoCAL® automatic internal calibration with real-time temperature monitoring and drift compensation
• Chemically resistant housing — fully acetone-cleanable surface and corrosion-tolerant mechanical components
• Draft shield with electrostatic coating on all glass surfaces to suppress charge-induced weighing errors
• Integrated in-use cover and dedicated storage dust cover for extended protection during non-operational periods
• Kensington lock slot for physical security integration in shared or open-lab environments
• Regulatory-ready firmware with configurable user access levels, tamper-evident calibration logs, and GLP/GMP-compliant print output
• Direct Windows®-compatible data transmission via mini-USB; no proprietary drivers required
• Plug-and-play compatibility with Sartorius YDP series thermal printers for immediate hardcopy generation

Sample Compatibility & Compliance

The Secura accommodates standard analytical samples up to 60 g with optimal stability across diverse material classes — including hygroscopic powders, volatile solvents, fine ceramics, and pharmaceutical actives. Its 80 mm diameter stainless-steel weighing pan and 218 mm draft chamber height permit safe handling of tall or irregularly shaped containers. All models are supplied with CMC certification (PRC) and conform to OIML R76-1 international recommendations for non-automatic weighing instruments. For regulated users, the balance supports 21 CFR Part 11 readiness when paired with Sartorius LabX software (optional), enabling electronic signatures, role-based permissions, and secure audit trail archiving. Routine verification procedures align with ASTM E898, ISO 17025 clause 6.5.2, and USP <1251> guidelines for analytical balance qualification.

Software & Data Management

While the Secura operates autonomously via its onboard firmware, it is natively interoperable with Sartorius LabX™ — a validated, server-based laboratory software platform supporting full digital workflow automation. Direct USB connection enables seamless export of raw mass values, timestamps, operator IDs, calibration events, and environmental metadata (e.g., ambient temperature, humidity if external sensors are connected) into CSV, Excel, or LIMS-compatible formats. All print outputs include mandatory GLP headers: date/time stamp, balance ID, operator ID, calibration status, and uncertainty statement (when configured). Audit trail records preserve chronological integrity of all critical actions — including zeroing, calibration, unit changes, and parameter modifications — with immutable timestamps and user attribution.

Applications

The Secura serves as a foundational instrument across QA/QC laboratories, R&D centers, and academic teaching facilities. Primary use cases include: quantitative sample preparation for HPLC and ICP-MS analysis; active pharmaceutical ingredient (API) dispensing per pharmacopeial monographs; density determination using Archimedean principle with auxiliary kits; statistical process control (SPC) via built-in counting and checkweighing functions; formulation of multi-component mixtures with real-time % deviation feedback; and stability-indicating assays requiring sub-10 mg repeatability. Its robust design also supports field-deployable applications in mobile labs and cleanroom annexes where vibration isolation tables (e.g., optical-grade granite platforms) are employed to mitigate structural resonance.

FAQ

Does the Secura support external environmental sensors for temperature/humidity compensation?
Yes — optional RS232 or USB-connected Sartorius Humidity/Temperature Sensors (e.g., HUMIC 100) can be integrated to enable dynamic buoyancy correction per ISO 8655-5.
Is isoCAL® compliant with ISO/IEC 17025 accreditation requirements for calibration frequency?
Yes — isoCAL® satisfies clause 7.8.1 of ISO/IEC 17025:2017 by providing documented, automated, and traceable calibration events that reduce reliance on external service intervals.
Can the Secura be validated according to GxP requirements without LabX?
Basic IQ/OQ protocols are provided in the manufacturer’s Validation Guide (Doc. No. 98048-001); however, full PQ execution and electronic record retention require LabX or third-party ELN/LIMS integration.
What is the recommended maintenance interval for the Secura under continuous operation?
Sartorius recommends quarterly performance verification using certified test weights (Class E2 or better) and annual preventive maintenance by authorized service technicians.
Does the balance retain calibration data after power loss?
Yes — all calibration parameters, historical logs, and user settings are stored in non-volatile flash memory and persist across power cycles and firmware updates.