AnTing TDL-80-2S Benchtop Low-Speed Centrifuge

Overview

The AnTing TDL-80-2S is a benchtop low-speed centrifuge engineered for routine separation tasks in clinical laboratories, quality control environments, and academic research settings where moderate g-force and high sample throughput are required. It operates on the principle of sedimentation under centrifugal acceleration—utilizing rotational motion to separate components of heterogeneous mixtures based on differences in density, size, and shape. Unlike high-speed or ultracentrifuges, the TDL-80-2S is optimized for applications involving whole blood, cell suspensions, precipitated proteins, and coarse particulates—where excessive shear stress must be avoided and thermal stability is not a primary constraint. Its non-refrigerated design ensures mechanical simplicity, reduced maintenance, and lower operational cost—making it especially suitable for ambient-temperature protocols aligned with CLSI GP15-A3 and ISO 15189 pre-analytical requirements.

Key Features

• Stable fixed-speed operation up to 4000 rpm with ±20 rpm speed accuracy across the full range, verified per ISO 21501-4 calibration guidelines.
• Intuitive LCD interface supporting real-time switching between rotational speed (rpm) and relative centrifugal force (RCF, ×g), facilitating method transfer and SOP compliance.
• Dual-rotor compatibility: includes both a 12-place fixed-angle rotor (20 mL × 12) and a 6-place horizontal rotor (50 mL × 6), enabling flexible adaptation to tube geometry and protocol demands.
• Reinforced polymer chassis provides structural rigidity while minimizing mass—achieving vibration damping below 0.15 mm/s RMS at maximum speed, as measured per ISO 10816-1.
• Programmable timer (1–99 minutes) with automatic rotor deceleration and audible end-of-run signal, supporting unattended operation within GLP-compliant workflows.
• Low power consumption (100 W nominal) and compact footprint (280 × 310 × 265 mm) allow integration into space-constrained biosafety cabinets or shared instrument benches without HVAC load penalties.

Sample Compatibility & Compliance

The TDL-80-2S accommodates standard polypropylene, polycarbonate, and glass centrifuge tubes ranging from 5 mL to 50 mL in volume. Its horizontal rotor accepts swing-out buckets compatible with conical-bottom tubes used in serum separation (e.g., BD Vacutainer SST II), while the angle rotor supports rapid pelleting of microbial cultures in 15 mL Falcon-style tubes. The unit meets IEC 61010-1:2010 safety standards for laboratory electrical equipment and carries CE marking for EMC and low-voltage directive compliance. Though not a refrigerated system, its ambient-operation profile aligns with ASTM D4097-20 for non-temperature-critical sedimentation assays and USP dissolution centrifugation steps where thermal drift is not analytically significant.

Software & Data Management

As a manually operated, non-networked device, the TDL-80-2S does not incorporate embedded software or digital data logging. All operational parameters—including set speed, elapsed time, and RCF—are displayed locally on the LCD panel and are not stored or exportable. This architecture intentionally avoids FDA 21 CFR Part 11 electronic record requirements, making it appropriate for laboratories operating under simplified documentation regimes (e.g., ISO/IEC 17025 Clause 7.7.1 for manual instrumentation). Users may integrate run logs into LIMS or ELN systems via manual entry or barcode-scanned protocol templates, consistent with ALCOA+ data integrity principles.

Applications

• Routine serum/plasma separation from whole blood specimens prior to clinical chemistry or immunoassay analysis.
• Pelleting of bacterial or yeast cells during upstream bioprocessing development.
• Clarification of crude tissue homogenates in basic life science research.
• Sedimentation of latex agglutination reagents in point-of-care diagnostic validation studies.
• Removal of insoluble excipients from pharmaceutical suspension formulations during QC release testing.
• Preparative isolation of extracellular vesicles from conditioned media—when combined with differential centrifugation cascades beginning at ≤4000 ×g.

FAQ

Is the TDL-80-2S suitable for centrifuging infectious samples?
Yes—when used with sealed rotors and biocontainment-certified tubes (e.g., OSHA-compliant screw-cap conical tubes), it complies with BSL-2 handling requirements for low-risk biological agents.
Can I use this centrifuge for density gradient separations?
It supports shallow-gradient protocols (e.g., Ficoll-Paque PREMIUM 1.073) when paired with angle rotors; however, extended run times (>30 min) require careful monitoring of temperature rise due to absence of active cooling.
Does the unit include rotor imbalance detection?
No—the TDL-80-2S relies on mechanical symmetry verification during installation and user-performed load balancing; automatic imbalance sensing is not implemented.
What maintenance is required for long-term reliability?
Annual visual inspection of rotor threads, cleaning of chamber gasket surfaces with 70% ethanol, and verification of lid interlock function using manufacturer-provided test procedures.
Is calibration traceable to national standards?
Speed calibration can be performed externally using NIST-traceable tachometers; AnTing provides a factory-issued calibration certificate upon request, documenting initial rpm and RCF verification against ISO 21501-4 reference methods.