GBPI N500-cc Differential Pressure Gas Permeability Analyzer
| Brand | GBPI |
|---|---|
| Origin | Guangdong, China |
| Manufacturer Type | Direct Manufacturer |
| Country of Origin | China |
| Model | N500-cc |
| Price Range | USD 14,000 – 70,000 |
| Test Gases | O₂, CO₂, N₂ |
| Measurement Principle | Differential Pressure (Manometric) Method |
| Test Range | 0.02–50,000 cm³/(m²·24h·0.1 MPa), extendable to 600,000 cm³/(m²·24h·0.1 MPa) |
| Accuracy | 0.001 cm³/(m²·24h·0.1 MPa) |
| Temperature Control Range | 15–60 °C |
| Temperature Stability | ±0.1 °C |
| Vacuum Level | <20 Pa |
| Vacuum Resolution | 0.01 Pa |
| Test Pressure Range | −0.1 to +0.1 MPa |
| Gas Supply Pressure | 0.2–0.8 MPa |
| Sample Area | 50.24 cm² |
| Sample Diameter | Φ110 mm |
| Max. Sample Thickness | ≤2 mm |
| Chamber Capacity | Single-test cavity |
| Dimensions | 700 × 600 × 450 mm |
| Weight | 41.7 kg |
| Power | 500 W |
| Electrical Supply | AC 220 V, 50 Hz |
| Compliance | GB/T 1038–2000, ISO 2556:1974, ISO 15105-1:2007, ASTM D1434, YBB 00082003–2015, JIS K7126-1:2006 |
Overview
The GBPI N500-cc Differential Pressure Gas Permeability Analyzer is an engineered solution for precise quantification of gas transmission rates (GTR) through polymeric films, laminates, foils, and rigid packaging structures. It operates on the differential pressure (manometric) principle—compliant with internationally recognized gravimetric and manometric test methodologies—where a controlled pressure gradient is established across a conditioned specimen sealed between two isolated chambers. The upstream chamber is pressurized with a defined test gas (O₂, CO₂, or N₂), while the downstream chamber is maintained under high vacuum. Gas permeation through the sample induces a measurable pressure rise in the downstream cavity, which is continuously monitored via high-resolution capacitive pressure transducers. Real-time data acquisition enables calculation of gas transmission rate per unit area, time, and partial pressure difference—expressed in standardized units of cm³/(m²·24h·0.1 MPa). This method delivers traceable, reproducible results essential for regulatory submissions, material qualification, and shelf-life modeling in pharmaceutical, food, medical device, and advanced electronics packaging applications.
Key Features
- High-fidelity differential pressure measurement with 0.01 Pa vacuum resolution and ±0.1 °C thermal stability—ensuring repeatability under GLP/GMP-compliant conditions.
- Integrated ARM-based embedded control system enabling standalone operation; no external PC required for routine testing.
- Full automation of vacuum evacuation, gas dosing, pressure equilibration, constant-delta-P maintenance, and thermal conditioning—all programmable via intuitive 7-inch color touchscreen interface.
- Three-tier barrier sensitivity modes (low/medium/high阻隔) optimized for materials ranging from standard PE films to ultra-high-barrier aluminum-coated substrates and SiOₓ-coated PET.
- Modular cavity design supporting optional accessories for container testing (bottles, pouches, trays) and extended-range measurements up to 600,000 cm³/(m²·24h·0.1 MPa) using calibrated volume expansion modules.
- Comprehensive audit trail functionality compliant with FDA 21 CFR Part 11 and EU Annex 11 requirements—including user role-based access control (administrator/operator/observer), method versioning, and immutable event logging for all parameter changes, test initiations, and data exports.
Sample Compatibility & Compliance
The N500-cc accommodates flat specimens up to Φ110 mm and 2 mm thick—including monolayer plastics (LDPE, PP, PET), metallized films (AlOx, SiOx), laminates (PET/AL/PE, NY/AL/RCPP), elastomers, ceramics, and coated substrates used in flexible electronics and biomedical devices. With optional fixtures, it extends to rigid and semi-rigid containers (e.g., blister packs, HDPE bottles, CPET trays) following ASTM F2622 and ISO 15105-2 protocols. All hardware and firmware are validated against primary national and international standards: GB/T 1038–2000 (China), ISO 2556:1974 and ISO 15105-1:2007 (global harmonization), ASTM D1434 (U.S.), JIS K7126-1:2006 (Japan), and YBB 00082003–2015 (Chinese pharmaceutical packaging). Instrument calibration is traceable to GBW(E)130541/2 certified reference materials issued by the State Administration for Market Regulation (SAMR), ensuring metrological equivalence across global laboratories.
Software & Data Management
The embedded GBPI PermeaSoft™ v4.x platform provides real-time visualization of pressure, differential pressure, temperature, and cumulative gas transmission curves—with adjustable time-axis scaling, overlay capability, and on-screen curve hiding/preview toggles. Test methods are fully configurable: users define ramp rates, hold durations, target delta-P values, and pass/fail thresholds. Reports auto-generate in bilingual (English/Chinese) format and export natively to PDF, XLSX, and DOCX without third-party dependencies. All raw sensor data—including timestamped pressure transients and thermal profiles—are stored in a local SQLite database with SHA-256 hashing for integrity verification. Exported files retain embedded digital signatures and full audit metadata, satisfying data integrity requirements under ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available).
Applications
This analyzer supports critical quality control and R&D workflows across regulated and industrial sectors. In pharmaceutical packaging, it validates O₂ ingress into blister cavities and moisture-sensitive vials per USP and ICH Q5C guidelines. Food manufacturers employ it to benchmark CO₂ loss from modified-atmosphere packaging (MAP) and assess aroma barrier performance of snack pouches. Electronics producers quantify helium leakage through encapsulation films for OLED displays and flexible PCBs. Medical device firms evaluate gas exchange kinetics in wound dressings and transdermal patches per ISO 10993-12. Additionally, solar panel manufacturers rely on its high-range extension mode to characterize water vapor and oxygen transmission through backsheet laminates (e.g., ETFE/EVA/PO) per IEC 61215 standards.
FAQ
Does the N500-cc support multi-gas testing without hardware modification?
Yes—gas-specific calibration factors are pre-loaded for O₂, CO₂, and N₂; switching gases requires only selection of the corresponding calibration profile and verification using certified reference films.
Can test data be integrated into a LIMS environment?
Yes—via optional OPC UA or RESTful API module (sold separately), enabling bidirectional data exchange with laboratory information management systems compliant with ASTM E1578 and ISO/IEC 17025.
Is vacuum pump maintenance included in routine service?
The built-in dual-stage diaphragm vacuum pump is rated for >10,000 hours MTBF; GBPI recommends annual oil-free filter replacement and leak-check validation as part of preventive maintenance.
How is instrument accuracy verified between calibrations?
Users may perform daily system suitability checks using GBPI-certified permeation standards (e.g., 100 cm³/m²·24h·0.1 MPa O₂ film), with automatic deviation alerts triggered if measured values exceed ±2% of certified value.
What documentation is provided for regulatory audits?
Each unit ships with Factory Acceptance Test (FAT) report, IQ/OQ protocol templates, 21 CFR Part 11 compliance statement, and metrological traceability certificate linked to SAMR-accredited reference materials.
