Xiangyi CHT210R High-Capacity High-Speed Refrigerated Benchtop Centrifuge

Overview

The Xiangyi CHT210R is a high-capacity, high-speed refrigerated benchtop centrifuge engineered for demanding applications in molecular biology, clinical diagnostics, and biopharmaceutical research. It operates on the principle of sedimentation under controlled centrifugal force, enabling efficient separation of biomacromolecules—including proteins, nucleic acids (DNA/RNA), subcellular organelles, and mammalian cells—based on differences in density, size, and shape. Its refrigerated operation maintains sample integrity during prolonged or heat-sensitive protocols, with precise temperature control ranging from −20 °C to +40 °C. Designed for routine and advanced laboratory workflows, the CHT210R integrates industrial-grade thermal management, intelligent rotor recognition logic, and robust mechanical architecture to ensure long-term reliability and reproducible separation outcomes.

Key Features

• Advanced dual-channel variable-frequency refrigeration system with PID dynamic temperature regulation—ensures ±0.5 °C temperature stability across the full operating range and minimizes thermal drift during extended runs.
• 7-inch high-sensitivity capacitive touchscreen (800 × 480 resolution), glove-compatible interface supporting direct numeric entry; all setpoints and real-time operational parameters (speed, RCF, time, temperature, rotor ID) are displayed simultaneously for unambiguous monitoring.
• Programmable pre-cooling function with rotor-specific presets and scheduled start capability—enables automatic chill-down prior to user arrival, reducing experimental downtime.
• AC brushless frequency-controlled motor delivering exceptional speed accuracy (< ±10 rpm) and zero carbon dust generation—eliminates maintenance requirements associated with brushed motors and enhances contamination control in sterile environments.
• Flexible multi-step protocol support: up to five sequential programs can be chained into a single run (stepwise centrifugation); 100 user-named protocols stored internally for traceable method recall and GLP-compliant experiment replication.
• Customizable acceleration/deceleration profiles: 11 preset ramp-up curves, 12 ramp-down curves, and 10 fully user-defined deceleration levels—critical for pelleting fragile particles or preventing resuspension of delicate pellets.
• Automatic logging of operational history and fault events—including timestamped run records, error codes, and rotor usage metrics—supports internal audit readiness and preventive maintenance planning.

Sample Compatibility & Compliance

The CHT210R accommodates standard horizontal rotors compatible with 15 mL, 50 mL conical tubes, microtubes, and swing-out buckets up to 750 mL capacity per position (4 × 750 mL total). All optional sealed buckets meet ISO 13485-certified leak-tightness standards for biosafety level 2 (BSL-2) containment. The instrument complies with IEC 61010-1:2010 for electrical safety and IEC 61326-1:2013 for electromagnetic compatibility. While not FDA 21 CFR Part 11–validated out-of-the-box, its audit-trail-capable event logging and password-protected program editing align with GLP/GMP documentation requirements when integrated into validated laboratory workflows.

Software & Data Management

The embedded firmware supports local data persistence without external software dependency. All run logs—including start/stop timestamps, actual vs. set RCF, final temperature deviation, and rotor serial tracking—are retained onboard for ≥10,000 cycles. Optional USB export enables transfer of CSV-formatted run reports for integration into LIMS or ELN systems. No cloud connectivity or proprietary desktop software is required; configuration and diagnostics remain fully accessible via the native touchscreen UI.

Applications

• Purification of plasmid DNA, genomic DNA, and total RNA from lysates using silica-membrane or phenol-chloroform extraction workflows.
• Isolation of exosomes, microvesicles, and extracellular nanoparticles via differential ultracentrifugation (with compatible fixed-angle rotor adapters).
• Clinical specimen processing: serum/plasma separation from whole blood, PBMC isolation, and viral pellet concentration for downstream PCR or sequencing.
• Protein fractionation and organelle enrichment (e.g., mitochondria, nuclei) in cell homogenates under chilled conditions.
• Quality control testing in biomanufacturing: clarification of monoclonal antibody harvests and removal of host cell debris at pilot scale.

FAQ

What is the minimum temperature achievable during operation?
The CHT210R achieves a stable setpoint as low as −20 °C, with typical stabilization time of ≤15 minutes from ambient (25 °C) using the pre-cool function.
Does the centrifuge support automatic rotor identification?
Yes—integrated RFID-based rotor recognition ensures correct maximum speed and RCF limits are enforced per installed rotor type, preventing over-speed incidents.
Can run data be exported for regulatory documentation?
Yes—USB port allows export of timestamped run logs in CSV format, including operator ID (if enabled), rotor ID, and parameter deviations—suitable for internal QA review.
Is this model suitable for GMP-regulated environments?
It meets core hardware prerequisites for GMP use (traceable operation, secure parameter locking, and audit-ready logs); however, site-specific validation (IQ/OQ/PQ) and procedural SOP alignment remain the responsibility of the end-user.
What safety certifications does the CHT210R hold?
It conforms to IEC 61010-1 (safety) and IEC 61326-1 (EMC); rotor assemblies comply with ISO 13485 for medical device manufacturing quality systems.