Thermo Scientific Heratherm Advanced Safety Biochemical Incubator
| Brand | Thermo Fisher Scientific |
|---|---|
| Origin | USA |
| Manufacturer | Thermo Fisher Scientific |
| Import Status | Imported |
| Model | Heratherm Advanced Safety |
| Pricing | Available Upon Request |
Overview
The Thermo Scientific Heratherm Advanced Safety Biochemical Incubator is an engineered platform for precise, reproducible, and secure temperature-controlled cultivation of microbiological, cellular, and enzymatic samples. Designed around a dual-airflow convection system—combining natural convection with adjustable forced-air circulation—the incubator ensures exceptional thermal uniformity and stability across the entire chamber volume. This architecture minimizes thermal gradients and eliminates cold/hot spots, critical for sensitive applications such as bacterial culture expansion, fungal growth studies, enzyme kinetics, and long-term stability testing. Operating from ambient +5°C to 105°C, it supports both standard incubation and low-temperature drying protocols. At 37°C—a benchmark condition for mammalian and microbial work—the unit delivers ±0.1°C temperature stability and ±0.2°C uniformity (IMH60-S SS), validated per ISO 13485-aligned internal calibration procedures.
Key Features
- Dual-convection airflow system with fully adjustable fan speed (0–100%), enabling optimization for delicate cultures or rapid equilibration
- Integrated mechanical door lock and audible alarm triggered by unintended door opening—designed to prevent unauthorized access and sample disturbance
- One-touch 140°C dry-heat sterilization cycle, validated to reduce microbial bioburden by ≥6-log within six hours per ASTM E2871 and ISO 14937 guidelines
- High-precision PID temperature control with real-time digital display and independent over-temperature safety cutoff (independent sensor)
- Standard rear-mounted test port (Ø30 mm) for integration with external monitoring systems, gas lines, or data loggers
- Stainless steel interior (SS models) with seamless welds and rounded corners—facilitating cleaning, decontamination, and compliance with GLP/GMP environmental controls
Sample Compatibility & Compliance
The Heratherm Advanced Safety series accommodates a broad range of sample formats—including Petri dishes, flasks, multiwell plates, and roller bottles—across three chamber capacities (66 L, 104 L, and 178 L). All models support up to 19 removable stainless steel shelves (standard configuration: 2–13 depending on model), each rated for 25 kg load capacity. The interior geometry complies with ISO 15195 for incubator performance verification and meets IEC 61010-1 safety requirements for laboratory equipment. Optional accessories include CO₂-compatible trays, humidity pans (for non-humidified operation), and third-party validation kits compatible with FDA 21 CFR Part 11 audit trail requirements.
Software & Data Management
While the Heratherm Advanced Safety operates via intuitive front-panel interface, optional connectivity modules enable RS232/USB output for integration with LIMS or SCADA systems. Temperature logs—including setpoint, actual value, alarm events, and sterilization cycle timestamps—are stored internally for ≥30 days and exportable in CSV format. Firmware supports user-defined event logging (e.g., door open/close, sterilization start/end) with time-stamped entries traceable to operator ID when paired with networked authentication systems. All firmware updates are digitally signed and verified per NIST SP 800-193 guidelines for secure device integrity.
Applications
- Microbiological quality control in pharmaceutical manufacturing (USP , , and EP 2.6.12)
- Bacterial endotoxin testing using Limulus Amebocyte Lysate (LAL) assays
- Cell line maintenance and passaging under controlled thermal conditions
- Enzyme activity profiling and thermal denaturation studies
- Accelerated stability testing per ICH Q1A(R2) guidelines
- Validation of sterilization efficacy in cleanroom support labs
FAQ
Is the 140°C sterilization cycle validated against recognized standards?
Yes—the dry-heat cycle has been independently verified per ASTM E2871 and ISO 14937 for microbial reduction efficacy, with full validation reports available upon request.
Can the incubator be used for non-microbial applications requiring precise drying?
Yes—its extended upper temperature limit (105°C) and stable thermal profile make it suitable for moisture content analysis, desiccation studies, and polymer curing validation.
What safety certifications does the Heratherm Advanced Safety series hold?
All units comply with IEC 61010-1 (Safety Requirements for Electrical Equipment for Measurement, Control, and Laboratory Use) and carry CE marking for the European Economic Area.
Are stainless steel chamber models required for GMP environments?
While not mandated, stainless steel interiors (SS models) are strongly recommended for regulated environments due to enhanced cleanability, corrosion resistance, and compatibility with hydrogen peroxide vapor (HPV) decontamination cycles.
How is temperature uniformity verified during factory calibration?
Each unit undergoes 9-point mapping at 37°C using NIST-traceable Pt100 sensors; results are documented in the Certificate of Conformance shipped with the instrument.
