LuXiangYi TDL-8M Benchtop High-Capacity Refrigerated Centrifuge
| Brand | LuXiangYi / BIORIDGE |
|---|---|
| Origin | Shanghai, China |
| Model | TDL-8M |
| Instrument Type | Benchtop Centrifuge |
| Speed Range | 0–8000 rpm |
| Max RCF | 9100 × g |
| Max Capacity | 4 × 250 mL |
| Temperature Range | −5°C to +35°C |
| Temp Control Accuracy | ±1°C |
| Noise Level | <65 dB(A) |
| Power Supply | AC 220 V, 50 Hz, 15 A |
| Dimensions (L×W×H) | 460 × 710 × 420 mm |
| Net Weight | 80 kg |
| Rotor Types | Horizontal swing-out rotors (standard), including 250 mL × 4, 100 mL × 8, 7 mL × 48/72, and 96-well microplate carriers |
| Drive System | Microprocessor-controlled AC frequency conversion motor |
| Safety Features | Electronic lid lock, overspeed protection, overtemperature protection, automatic fault alarm |
| Acceleration/Deceleration Profiles | 9 programmable ramp curves |
| Timer Range | 1–99 min |
| Speed Accuracy | ±30 rpm |
Overview
The LuXiangYi TDL-8M Benchtop High-Capacity Refrigerated Centrifuge is a precision-engineered separation platform designed for routine and high-throughput applications in clinical diagnostics, molecular biology, biochemistry, immunology, and academic research laboratories. Operating on the principle of sedimentation under controlled gravitational force (RCF), this instrument enables reliable pelleting of large cellular components—including nuclei, mitochondria, lysosomes, and viral particles—while maintaining sample integrity through active temperature regulation. Its benchtop footprint integrates industrial-grade refrigeration (−5°C to +35°C), robust mechanical stability, and microprocessor-driven control logic—making it suitable for environments requiring consistent thermal management during extended centrifugation cycles. Unlike compact microcentrifuges or floor-standing ultracentrifuges, the TDL-8M occupies a functional niche: high-volume, low-to-moderate speed separations where both capacity and thermal control are critical.
Key Features
- AC Frequency Conversion Drive: A high-torque, brushless AC motor ensures stable rotational performance across the full speed range (0–8000 rpm), minimizing mechanical wear and delivering reproducible acceleration profiles with ±30 rpm speed accuracy.
- Intelligent Thermal Management: Equipped with an imported high-efficiency compressor and environmentally compliant R22a refrigerant, the system maintains setpoint temperature within ±1°C across all operating conditions—even during prolonged runs at maximum load.
- Programmable Ramp Control: Nine independent acceleration and deceleration curves allow users to optimize pelleting kinetics for sensitive samples (e.g., intact organelles or antibody-antigen complexes), reducing shear-induced aggregation or resuspension.
- Human-Centered Interface: A capacitive touch panel with real-time dual-display (rpm and RCF) enables intuitive parameter entry, immediate unit conversion, and persistent storage of up to nine user-defined protocols.
- Multi-Layer Safety Architecture: Integrated electronic lid interlock prevents operation unless fully closed; redundant monitoring detects overspeed, overtemperature, imbalance, and rotor failure—triggering audible/visual alarms and immediate shutdown per IEC 61010-2-020 safety standards.
- Acoustic Optimization: Vibration-dampened rotor chamber, balanced drive assembly, and acoustic insulation reduce operational noise to <65 dB(A), supporting use in shared lab spaces without compromising workflow continuity.
Sample Compatibility & Compliance
The TDL-8M supports a broad spectrum of sample formats via interchangeable horizontal rotors: four 250 mL bottles (ideal for cell culture harvests), eight 100 mL tubes (with optional 10/20 mL adapters), up to 72 × 7 mL microtubes (for high-density plasma or serum processing), and eight standard 96-well plates (enabling parallel ELISA or PCR plate clearing). All rotors are certified for continuous operation at rated speeds and undergo static/dynamic balancing per ISO 15841. The instrument complies with electromagnetic compatibility (EMC) requirements under EN 61326-1 and electrical safety directives per EN 61010-1. While not FDA 510(k)-cleared as a medical device, its design aligns with CLIA and CAP guidelines for clinical centrifugation workflows, and temperature logging functionality supports GLP/GMP audit readiness when paired with external data loggers.
Software & Data Management
The TDL-8M operates as a standalone instrument with embedded firmware—no PC dependency required for routine operation. All run parameters (time, speed, temperature, ramp profile, rotor ID) are timestamped and stored locally in non-volatile memory for traceability. Though no proprietary software suite is included, the interface supports manual export of session logs via USB port (optional accessory), enabling integration into LIMS or electronic lab notebooks (ELN) via CSV formatting. Audit trail capabilities meet baseline requirements for ISO/IEC 17025-accredited testing laboratories, particularly when combined with procedural SOPs governing rotor calibration, preventive maintenance, and temperature verification (e.g., using NIST-traceable thermistors).
Applications
- Clinical: Separation of whole blood into serum/plasma fractions; isolation of PBMCs from leukapheresis products; preparation of platelet-rich plasma (PRP) for regenerative medicine protocols.
- Biotechnology: Harvesting bacterial or yeast cultures prior to lysis; clarification of crude lysates containing inclusion bodies or membrane vesicles.
- Academic Research: Fractionation of subcellular organelles from tissue homogenates; concentration of lentiviral or AAV vectors; removal of debris from CRISPR ribonucleoprotein (RNP) complexes prior to electroporation.
- Quality Control: Stability testing of protein therapeutics under accelerated temperature conditions; particulate matter analysis in ophthalmic solutions per USP .
FAQ
What is the maximum relative centrifugal force (RCF) achievable with the TDL-8M, and at what rotor configuration?
The maximum RCF of 9100 × g is attained using the 100 mL × 8 rotor at 8000 rpm.
Can the TDL-8M maintain −5°C during continuous operation at full capacity?
Yes—the refrigeration system is engineered for sustained cooling under maximum load, verified per manufacturer thermal load testing protocols.
Are rotor calibrations traceable to national standards?
Rotors are dynamically balanced per ISO 15841; users are advised to perform periodic speed calibration using an external tachometer traceable to NIST or equivalent metrology institute.
Does the instrument support 24/7 unattended operation?
While the timer limits runtime to 99 minutes per cycle, automated restart after power recovery is not supported; continuous operation requires manual re-initiation.
Is the R22a refrigerant compliant with current EU F-Gas Regulation (EU) No 517/2014?
R22a is classified as a hydrocarbon blend with negligible global warming potential (GWP <15); it is permitted for laboratory equipment under Annex III exemptions for low-charge systems.
