LuXiangYi TG1850-WS Benchtop High-Speed Centrifuge

Overview

The LuXiangYi TG1850-WS is a microprocessor-controlled benchtop high-speed centrifuge engineered for precision separation of biological and clinical samples under demanding laboratory conditions. Utilizing a brushless DC motor drive system, it delivers stable rotational dynamics with minimal mechanical vibration and acoustic emission—critical for reproducible pelleting of subcellular organelles, nucleic acids, viruses, and protein complexes. Designed for routine use in hospital core labs, academic research facilities, and biotechnology QA/QC environments, the TG1850-WS operates within the high-speed centrifugation range (10,000–30,000 rpm), achieving a maximum relative centrifugal force (RCF) of 23,797 × g at its rated speed of 18,500 rpm. Its compact footprint (330 × 420 × 280 mm) enables integration into space-constrained biosafety cabinets or shared instrumentation benches without compromising thermal management or structural rigidity.

Key Features

• Brushless DC motor with closed-loop speed regulation ensures long-term torque consistency and eliminates carbon brush wear—reducing maintenance intervals and enhancing operational longevity.
• Intuitive capacitive touch interface with backlit LCD display supports real-time switching between rpm and RCF readouts, enabling rapid protocol translation across rotor configurations.
• Programmable acceleration/deceleration profiles (9 preset curves) allow optimization of sedimentation kinetics—minimizing sample resuspension during braking, especially critical for fragile pellets such as lymphocytes or exosomes.
• Integrated electronic lid lock with dual-sensor interlock prevents operation unless the rotor chamber is fully sealed; automatic detection triggers immediate rotor deceleration if lid displacement exceeds safety thresholds.
• Multi-layer protection suite includes overspeed shutdown, imbalance detection (>5 g differential), rotor recognition via embedded ID chip (for compatible rotors), and overtemperature monitoring of motor windings and bearing housings.
• Auto-save memory retains up to 9 user-defined protocols—including speed, time, RCF, and ramp settings—with timestamped recall for audit-ready workflow continuity.

Sample Compatibility & Compliance

The TG1850-WS accepts a comprehensive suite of fixed-angle rotors certified for ISO 13485-aligned manufacturing and validated per ASTM F2119-22 (Centrifuge Performance Verification). Standard configurations support tubes ranging from 0.2 mL PCR strips to 100 mL conical centrifuge bottles, with adapter compatibility for 0.5 mL, 1.5 mL, 2.2 mL, 5 mL, 10 mL, 15 mL, 20 mL, and 50 mL formats. Rotors are manufactured from high-strength aluminum alloy (6061-T6) and undergo hydrostatic pressure testing at 1.5× rated RCF prior to release. The instrument complies with IEC 61010-1:2010 for electrical safety and IEC 61326-1:2013 for electromagnetic compatibility (EMC). Its firmware architecture supports optional GLP/GMP audit trails—including operator ID tagging, parameter change logs, and electronic signature fields—when paired with validated LIMS interfaces.

Software & Data Management

While the TG1850-WS operates as a standalone instrument, its embedded controller exports timestamped run logs (CSV format) via USB port for integration into laboratory information management systems (LIMS). Each log entry records rotor ID, start/stop timestamps, actual vs. set rpm/RCF, total runtime, energy consumption (kWh), and fault codes (if triggered). All data fields conform to ISO/IEC 17025:2017 clause 7.5.2 on record control. Optional firmware updates—distributed through LuXiangYi’s secure portal—include enhanced calibration traceability (NIST-traceable reference standards), expanded rotor database validation, and improved error diagnostics aligned with FDA 21 CFR Part 11 Annex 11 requirements for electronic records integrity.

Applications

• Clinical diagnostics: Rapid isolation of plasma, serum, PBMCs, and urinary sediments per CLSI GP44-A4 guidelines.
• Molecular biology: Pellet recovery of plasmid DNA, genomic DNA, RNA, and CRISPR ribonucleoprotein complexes following phenol-chloroform extraction or silica-column purification.
• Virology & cell therapy: Concentration of lentiviral vectors, AAV particles, and extracellular vesicles using optimized low-shear deceleration profiles.
• Proteomics: Preparative fractionation of membrane proteins and protein aggregates prior to SDS-PAGE or mass spectrometry analysis.
• Quality control: Routine particulate matter removal from monoclonal antibody formulations and vaccine suspensions in compliance with USP and EP 2.9.19.

FAQ

Is the TG1850-WS compliant with FDA 21 CFR Part 11 for electronic records?
Yes—the instrument’s optional firmware upgrade enables audit trail generation, electronic signatures, and role-based access control required for regulated GxP environments.

Can I use this centrifuge for ultracentrifugation applications?
No. The TG1850-WS is classified as a high-speed centrifuge (max. 18,500 rpm), not an ultracentrifuge. It does not meet the vacuum chamber, rotor material, or bearing specifications required for >30,000 rpm operation.

Does the unit include rotor balancing verification tools?
Each rotor is pre-balanced at the factory and supplied with individual balance certification. Users must manually verify tube mass symmetry before loading; the instrument’s imbalance detection system will halt operation if load asymmetry exceeds ±5 g.

What is the recommended calibration interval?
Annual speed and temperature calibration is advised per ISO/IEC 17025. Certified calibration services—including NIST-traceable tachometer verification and RCF validation—are available through authorized LuXiangYi service centers.

Are rotors autoclavable?
Aluminum rotors are not autoclavable. They may be sterilized using 70% ethanol wipe-down or gas plasma methods. Stainless steel rotor variants (optional) support steam sterilization at 121°C for 20 minutes.