HNPM mzr-2921 Precision Micro-Dosing Peristaltic Pump

Overview

The HNPM mzr-2921 is a precision low-pressure micro gear metering pump engineered for high-reproducibility liquid handling in analytical instrumentation and automated laboratory systems. Based on positive displacement gear pumping technology, it delivers accurate, pulse-free flow with minimal shear stress—critical for preserving the integrity of sensitive reagents, calibration standards, and biological samples. Unlike peristaltic or syringe-based alternatives, the mzr-2921 employs a dual-gear rotor system with tight-tolerance machining and ceramic-coated bearings, enabling stable volumetric dosing across wide dynamic ranges without valve switching. Its design prioritizes long-term metrological stability under continuous operation, making it a core fluidic actuator in OEM-integrated platforms such as the Xantus liquid handling workstation.

Key Features

• Micro-scale dosing capability: Accurate delivery from 1 µL/h up to 1 L/min, supporting both ultra-trace reagent addition and bulk solvent transfer within a single platform.
• ±1% volumetric accuracy over full flow range—verified per ISO 5725-2 repeatability protocols—ensuring compliance with GLP and ISO/IEC 17025 traceability requirements.
• Integrated flush function at 40 mL/min enables rapid line clearance and cross-contamination mitigation between sample batches, essential for multi-analyte workflows.
• Compact footprint (≤ 85 × 55 × 40 mm) and low mass (< 320 g) facilitate seamless integration into space-constrained analytical instruments and robotic liquid handlers.
• Low-shear architecture preserves molecular integrity of proteins, enzymes, and nanoparticles; validated for use with aqueous buffers, polar organics (e.g., methanol, acetonitrile), and low-viscosity oils.
• Minimal maintenance design: No seals or diaphragms subject to fatigue; gear train lifetime exceeds 10,000 operating hours under nominal load conditions.

Sample Compatibility & Compliance

The mzr-2921 is qualified for contact with Class I–III fluids per USP and cytotoxicity/extraction testing. Wetted materials include PTFE, FFKM, and 316L stainless steel—compatible with aggressive solvents and mildly corrosive media. It meets CE marking requirements for electromagnetic compatibility (EN 61326-1) and safety (EN 61010-1). For regulated environments, the pump supports audit-ready operation when paired with host controllers compliant with FDA 21 CFR Part 11 (electronic records/signatures) and Annex 11 (computerized systems). Its pulse-dampened output satisfies ASTM D341 viscosity measurement prerequisites and ISO 8573-1 compressed air purity class 3 for ancillary pneumatic interfaces.

Software & Data Management

While the mzr-2921 operates as a standalone analog/digital-controlled actuator, its RS-485 Modbus RTU and 0–10 V analog input interfaces enable bidirectional communication with supervisory software (e.g., LabVIEW, Python-based PyModbus, or vendor-specific instrument control suites). Firmware supports programmable ramp profiles, dose-volume logging, and real-time flow verification via integrated Hall-effect speed monitoring. When deployed in multi-pump arrays—as in the Xantus platform—centralized calibration tables and error-code reporting (e.g., stall detection, thermal overload) are accessible via shared CAN bus infrastructure, facilitating preventive maintenance scheduling and IQ/OQ documentation.

Applications

• Automated liquid handling workstations requiring sub-microliter repeatability in genomics, clinical diagnostics, and drug discovery pipelines.
• OEM integration into HPLC autosamplers, ICP-MS sample introduction modules, and microfluidic assay readers.
• Continuous low-flow calibration delivery in environmental monitoring sensors (e.g., nutrient analyzers, dissolved oxygen probes).
• Controlled reagent injection in electrochemical cells, fuel cell test stands, and microreactor systems.
• High-throughput screening support where >8 parallel mzr-2921 units operate synchronously under centralized timing logic.

FAQ

What is the maximum allowable backpressure for continuous operation?
The mzr-2921 is rated for continuous duty at ≤ 2 bar (29 psi); operation above this threshold requires external pressure relief or flow restriction validation.
Can the pump handle viscous fluids such as glycerol or ethylene glycol?
It is optimized for kinematic viscosities ≤ 50 cSt at 20°C; higher viscosities necessitate derated flow rates and pre-heating to maintain accuracy.
Is firmware update capability available in-field?
Yes—via UART interface using HNPM’s proprietary configuration utility; updates preserve user-defined calibration offsets and operational history.
Does the pump support sterile or cleanroom-compatible installation?
Wetted path components meet ISO 14644-1 Class 5 cleanroom particulate limits when assembled under controlled conditions; optional EPDM-free configurations available upon request.
How is metrological traceability established for calibration?
Each unit ships with a factory calibration certificate traceable to PTB (Physikalisch-Technische Bundesanstalt) standards, including gravimetric flow verification at three points across the operational range.