OMNI International Prep Multi-Sample Homogenizer

Overview

The OMNI International Prep Multi-Sample Homogenizer is an engineered solution for high-throughput, reproducible mechanical lysis and homogenization of biological and soft-to-medium-hard tissue samples in research, clinical, and quality control laboratories. Utilizing rotor-stator (probe-type) shear principle, the system delivers controlled, scalable energy input via interchangeable stainless-steel or composite probes rotating at precisely regulated speeds—generating intense localized shear forces that disrupt cell membranes, emulsify suspensions, and disperse particulates without significant thermal buildup. Designed for walk-away operation in regulated environments, the Prep system integrates microprocessor-based speed and timing control with physical safeguards—including a transparent acoustic enclosure and vertically actuated sample rack—to ensure operator safety, sample integrity, and process consistency across batches.

Key Features

• Whisper™ brushless DC motor technology: Delivers quiet operation (< 75 dB[A]) and maintenance-free longevity with consistent torque output across the full 500–30,000 rpm range.
• Simultaneous 6-sample processing: Compatible with standard conical and round-bottom centrifuge tubes (1.5 mL, 2 mL, 5 mL, 15 mL, and 50 mL), enabling parallel homogenization without cross-contamination when used with disposable Omni Tip probes.
• Vertical sample rack actuation: Ensures uniform probe immersion depth and consistent shear exposure across all positions—critical for inter-sample reproducibility in quantitative workflows.
• Programmable microprocessor controller: Stores up to three user-defined protocols (speed + time), supporting repeatable method execution and audit-ready parameter logging.
• Acoustically shielded transparent enclosure: Reduces ambient noise while permitting real-time visual monitoring and preventing aerosol dispersion during high-speed operation.
• Modular probe ecosystem: Supports sterilizable stainless-steel probes (5 mm, 7 mm, 10 mm diameters; lengths up to 110 mm) and single-use or autoclavable Omni Tip probes—including soft-tissue, hard-tissue, and high-efficiency composite variants—each optimized for specific sample matrices and volume ranges (0.25–30 mL).

Sample Compatibility & Compliance

The Prep homogenizer accommodates diverse biological matrices including mammalian tissues (liver, spleen, muscle), cultured cells, plant material, bacterial pellets, and viscous lysates. Its probe geometry and speed calibration are validated for efficient lysis across ISO 11357-1 (polymer characterization), ASTM D4084 (emulsion stability), and USP (cell culture processing) contexts. The system complies with CE (2014/30/EU EMC Directive, 2014/35/EU LVD) and CSA C22.2 No. 61010-1 safety standards. When operated with traceable calibration records and logged protocols, it supports GLP and GMP-aligned workflows requiring documented instrument performance and data integrity per FDA 21 CFR Part 11 principles.

Software & Data Management

While the Prep operates via embedded hardware controls (no PC dependency), its programmable interface enables protocol versioning and manual entry of run parameters—facilitating integration into laboratory information management systems (LIMS) through standardized electronic lab notebook (ELN) templates. All stored programs retain timestamped execution history accessible via front-panel review. For facilities requiring full digital audit trails, optional RS-232 or USB-to-serial adapters allow connection to external data loggers compliant with ISO/IEC 17025 documentation requirements.

Applications

• High-yield nucleic acid and protein extraction from tissues and cell cultures
• Preparation of homogeneous suspensions for flow cytometry, ELISA, and mass spectrometry sample introduction
• Routine QC homogenization of pharmaceutical excipients and topical formulations
• Food safety testing: Pathogen enrichment media homogenization (e.g., Salmonella in ground meat)
• Environmental microbiology: Soil slurry and biofilm dispersion prior to microbial enumeration
• Biobanking: Standardized tissue aliquoting and cryopreservation matrix preparation

FAQ

What tube formats are supported without adapter modification?
Standard 1.5 mL, 2 mL, 5 mL, 15 mL, and 50 mL conical or round-bottom polypropylene centrifuge tubes—when used with the corresponding OEM tube racks.
Can Omni Tip probes be autoclaved?
Yes—Omni Tip soft-tissue and hard-tissue probes (catalog numbers ending in “H”) are rated for repeated autoclaving at 121 °C, 15 psi for 20 minutes. Composite tips require validation per institutional sterilization SOPs.
Is speed calibration traceable to NIST standards?
OMNI International provides factory calibration certificates upon request; field verification may be performed using ISO 17025-accredited tachometers per internal QA procedures.
How does vertical rack movement improve homogenization uniformity?
By dynamically adjusting probe depth relative to tube bottom, the system maintains constant tip-to-vessel geometry—eliminating variability caused by inconsistent manual probe positioning or liquid level differences between samples.
What electrical safety certifications apply to this unit?
CE marking per Low Voltage Directive 2014/35/EU and Electromagnetic Compatibility Directive 2014/30/EU; CSA C22.2 No. 61010-1:12 certification for laboratory equipment.