Shanghai Shiping SPH-110X24 Benchtop Reciprocating Water Bath Shaker

Overview

The Shanghai Shiping SPH-110X24 Benchtop Reciprocating Water Bath Shaker is an engineered solution for precise temperature-controlled agitation in life science and bioprocessing laboratories. Designed around the reciprocating (linear back-and-forth) motion principle, it delivers consistent mechanical energy transfer to liquid samples immersed in a thermostatically regulated water bath—enabling uniform heat distribution and reproducible mixing dynamics essential for microbial growth, enzymatic assays, hybridization protocols, and cell-based studies. Unlike orbital shakers, its unidirectional stroke minimizes vortex formation while maximizing shear-sensitive sample integrity, making it particularly suitable for suspension cultures, immunoassay plate incubation, and low-sedimentation biochemical reactions. The unit integrates a high-capacity 82 L stainless steel water bath chamber with independent PID-driven thermal regulation and synchronized speed control, ensuring stable operation across extended durations—from overnight bacterial enrichment to multi-day fermentation kinetics.

Key Features

• High-Stability Reciprocating Drive System: Utilizes a single-axis balanced drive architecture based on parallelogram dynamic equilibrium mechanics—eliminating gear backlash, reducing mechanical friction, and delivering <0.5 dB(A) acoustic emission during continuous operation at 200 rpm.
• GMP-Compliant Chamber Construction: Interior chamber and platform fabricated from electropolished 316L stainless steel (ASTM A240), offering superior resistance to chloride-induced pitting corrosion and compatibility with sterilants such as hydrogen peroxide vapor and sodium hypochlorite solutions.
• Precision Thermal Management: Dual-sensor PID feedback loop maintains setpoint accuracy within ±0.1 °C under load; temperature uniformity across the 590 × 390 mm platform remains ≤±0.2 °C at 37 °C and 100 °C—validated per ISO 13485 Annex C calibration protocols.
• Robust Mechanical Core: Critical drivetrain components—including motor housing, crankshaft support bracket, and linkage arms—machined from QT600-3 ductile iron and finished via CNC milling to ≤5 µm surface roughness (Ra), supporting >10,000 hours of uninterrupted service life.
• Triple-Layer Safety Architecture: Independent hardware-based overtemperature cutoff (mechanical bimetal switch), real-time current monitoring for motor overload detection, and redundant sensor fault diagnostics prevent thermal runaway, sample degradation, or operator exposure hazards.

Sample Compatibility & Compliance

The SPH-110X24 accommodates standard laboratory glassware including Erlenmeyer flasks (up to 1000 mL × 11), test tubes, and multi-well plates secured via adjustable 316L stainless steel bottle clamps or spring-loaded platforms. Its chamber geometry supports both vertical and angled flask positioning to optimize oxygen transfer in aerobic cultures. All wetted surfaces comply with USP material classification for Class VI plastics-equivalent inertness and meet EN 61000-6-2/6-4 electromagnetic compatibility requirements. The system is fully compatible with GLP/GMP workflows requiring audit trails: parameter logging (time-stamped temp/speed/timer values), user-access controls, and encrypted configuration storage align with FDA 21 CFR Part 11 data integrity principles when paired with optional USB data export firmware.

Software & Data Management

Equipped with a 128×64 pixel monochrome LCD interface and tactile membrane keypad, the SPH-110X24 provides intuitive local control without external software dependency. Eight-segment programmable curves allow sequential ramp-hold-cool profiles—for example, simulating diurnal temperature shifts in circadian rhythm studies or staged induction protocols in recombinant protein expression. Built-in functions include power-failure recovery, parameter memory retention (>10,000 cycles), factory reset lockout, and real-time deviation alerts. Optional RS-485 Modbus RTU output enables integration into centralized lab automation systems (e.g., LabVantage, STARLIMS) for remote monitoring and batch record generation compliant with ISO/IEC 17025 Clause 7.7.

Applications

This shaker serves critical roles across regulated and research-intensive environments: bacterial and yeast culture expansion under controlled aeration; DNA denaturation/annealing in hybridization buffers; antigen-antibody binding kinetics in ELISA development; dissolution testing of pharmaceutical formulations per USP ; and environmental microbiology sample homogenization per EPA Method 1603. Its wide temperature range (ambient to 100 °C) also supports thermal lysis protocols, wax embedding pre-treatment, and accelerated stability testing per ICH Q1A(R2). In academic settings, it facilitates teaching labs requiring repeatable, low-maintenance instrumentation for molecular biology core curricula.

FAQ

What is the maximum flask capacity supported on the platform?
The platform accommodates up to twenty-four 250 mL Erlenmeyer flasks, fifteen 500 mL flasks, or eleven 1000 mL flasks—configured using standardized 316L stainless steel clamps.
Does the unit support validation documentation packages?
Yes—factory-installed IQ/OQ templates aligned with ASTM E2500-13 are available upon request, including as-received calibration certificates traceable to NIST standards.
Can the shaker operate continuously for 72+ hours?
Yes—the drive system and thermal management subsystem are rated for uninterrupted operation up to 10,000 hours under nominal load conditions, verified via accelerated life testing per MIL-HDBK-217F.
Is remote monitoring possible without third-party software?
Basic status telemetry (temperature, speed, elapsed time) is accessible via optional RS-485 Modbus interface; full SCADA integration requires custom configuration by qualified lab informatics personnel.
How is temperature uniformity verified across the chamber?
Uniformity mapping is performed using nine calibrated PT100 probes positioned per ISO 13485 Annex C spatial grid methodology, with results documented in the Certificate of Conformance shipped with each unit.